A5084662083- Psychotherapy Techniques and Applications
- Psychiatric care and mental health services
- Child and Adolescent Psychosocial and Emotional Development
- Eating Disorders and Behaviors
- Schizophrenia research and treatment
- Personality Disorders and Psychopathology
- Mental Health Treatment and Access
- Mental Health Research Topics
- Mental Health and Psychiatry
- Hearing Impairment and Communication
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health and Patient Involvement
- Delphi Technique in Research
- Obsessive-Compulsive Spectrum Disorders
- Grief, Bereavement, and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Maternal Mental Health During Pregnancy and Postpartum
- Interpreting and Communication in Healthcare
- Health, psychology, and well-being
- COVID-19 Clinical Research Studies
- Forensic and Genetic Research
- Educational and Psychological Assessments
- Dental Implant Techniques and Outcomes
- Attachment and Relationship Dynamics
- Healthcare Systems and Technology
Universidad de Las Américas
2021-2025
University of the Americas
2025
Virginia Commonwealth University
2025
Noah's Ark Children's Hospital for Wales
2024
University of Roehampton
2017-2024
University of Sheffield
2012-2024
University of Cambridge
1983-2023
Wrightington, Wigan and Leigh NHS Foundation Trust
2023
Adaptimmune (United Kingdom)
2021
Oxford University Clinical Research Unit
2021
BACKGROUND: Mutations in the BRCA1 and BRCA2 genes are found most families with cases of both breast ovarian cancer or many early-onset cancer. However, an outbred population, prevalence mutations patients who were unselected for a family history this disease has not been determined. METHODS: detected blood samples from two population-based series young Britain. RESULTS: 15 (5.9%) 254 women diagnosed before age 36 years (nine [3.5%] six [ 2.4%] BRCA2) (4.1%) 363 ages through 45 (seven [1.9%]...
Background An acceptable, standardised outcome measure to assess efficacy and effectiveness is needed across multiple disciplines offering psychological therapies. Aims To present psychometric data on reliability, validity sensitivity change for the CORE–OM (Clinical Outcomes in Routine Evaluation – Outcome Measure). Method A 34-item self-report instrument was developed, with domains of subjective well-being, symptoms, function risk. Analysis includes internal test–retest socio-demographic...
Can different therapists, motivated by theories and working in settings, find a single measure - 'core' for monitoring their work? This paper introduces the Clinical Outcome...
To complement the evidence-based practice paradigm, authors argued for a core outcome measure to provide practice-based evidence psychological therapies. Utility requires instruments that are acceptable scientifically, as well service users, and coordinated implementation of at national level. The development Clinical Outcomes in Routine Evaluation-Outcome Measure (CORE-OM) is summarized. Data presented across 39 secondary-care services (n = 2,710) within an intensively evaluated single...
Where outcomes are unequivocal (life or death; being able to walk v paralysed) clinicians, researchers, and patients find it easy speak the same language in evaluating results. However, much of mental health work initial states treatments measured on continuous scales distribution “normal” often overlaps with range “abnormal.” In this situation, clinicians researchers talk different languages about change data, both probably poor at conveying their thoughts patients. Researchers...
Summary A series of editorials in this Journal have argued that psychiatry is the midst a crisis. The various solutions proposed would all involve strengthening psychiatry's identity as essentially ‘applied neuroscience’. Although not discounting importance brain sciences and psychopharmacology, we argue needs to move beyond dominance current, technological paradigm. This be more keeping with evidence about how positive outcomes are achieved could also serve foster meaningful collaboration...
The 34-item Body Shape Questionnaire (BSQ) has demonstrated sound psychometric properties in all samples reported to date (including this study). However, the unidimensional nature of 34 items suggests that BSQ may be unnecessarily long for use studies when body disparagement is not main focus investigation. This study 342 adult women presents two 16-item "alternate forms" which showed equivalent means and excellent internal consistency both derivation replication samples. Two 8-item scales...
Abstract Background : There is a need for generic, short, and easy‐to‐use assessment measure common presentations of psychological distress in UK primary care mental health settings. This paper sets out the development CORE‐10 response to this need. Method Items were drawn from CORE‐OM 10 items selected according combination usefulness, coverage item clusters, statistical procedures. Three datasets employed phase: (1) sample, (2) sample an MRC platform trial enhanced collaborative depression...
Background Measurement is the foundation of evidence-based practice. Advances in measurement procedures should extend to psychotherapy Aims To review developments relevant psychotherapy. Method Domains reviewed are: (a) interventions; (b) case formulation; (c) treatment integrity; (d) performance (including adherence, competence and skilfulness); (e) definitions; (f) therapeutic alliance; (g) routine outcome measurement. Results Modern methods can support ‘evidence-based practice’ for...
This study examined rates of improvement in psychotherapy as a function the number sessions attended. The clients (N=1,868; 73.1% female; 92.4% White; average age=40), who were seen for variety problems routine primary care mental health practices, attended 1 to 12 sessions, had planned endings, and completed Clinical Outcomes Routine Evaluation-Outcome Measure (CORE-OM) at beginning end their treatment. percentage achieving reliable clinically significant (RCSI) on CORE-OM did not increase...
Abstract The formation of ectopic bone within skeletal muscle is a widely observed phenomenon. However, the source osteoprogenitor cells responsible for remains unknown. This study was designed to test osteogenic differentiation among isolated from tissue. Different subpopulations derived an adult mouse were tested induction alkaline phosphatase activity after exposure morphogenetic protein‐2 in vitro. A responsive subpopulation identified, transduced with retrovirus encoding β‐galactosidase...
Background Many women may suffer psychological symptoms after stillbirth and in the subsequent pregnancy. Stillbirth has not been demonstrated previously to be a stressor for post-traumatic stress disorder (PTSD). Aims To assess incidence, correlates predictors of PTSD during pregnancy following stillbirth. Method A cohort study pregnant whose previous ended Results were prevalent Case-level was associated with depression, state-anxiety conception occurring closer loss. Symptomsgenerally...
<h3>Abstract</h3> <b>Objective:</b> To assess women9s symptoms of depression and anxiety during pregnancy the postpartum year in after stillbirth; to relevance time since loss. <b>Design:</b> Cohort study with four assessments: third trimester 6 weeks, months, 12 months birth. <b>Setting:</b> Outpatient departments three district general hospitals; subjects9 homes. <b>Subjects:</b> 60 women whose previous ended stillbirth 18 weeks9 gestation; matched controls. <b>Main outcome measures:</b>...
Extracapsular spread (ECS) in the cervical lymph nodes represents most significant adverse prognostic indicator oral squamous cell carcinoma (OSCC).In a consecutive cohort of OSCC treated by primary surgery, ECS was seen 25% (101) 400 patients.ECS doubled incidence local recurrence and distant metastases, but tripled regional failure. The recurrences occurred sooner than non-ECS cases (206 vs 334 days, p = .04). Patients with macroscopic had 5-year overall survival (OS) 19% compared 31%...