- Analytical Chemistry and Chromatography
- Enzyme Catalysis and Immobilization
- Carbohydrate Chemistry and Synthesis
- Coordination Chemistry and Organometallics
- African history and culture studies
- Mass Spectrometry Techniques and Applications
- Caribbean and African Literature and Culture
- Synthesis and Reactivity of Heterocycles
- Catalytic Cross-Coupling Reactions
- Ecology and Vegetation Dynamics Studies
- Chemical Synthesis and Analysis
- Glycosylation and Glycoproteins Research
- Lipid Membrane Structure and Behavior
- Nanoparticle-Based Drug Delivery
- Lysosomal Storage Disorders Research
- Botany and Plant Ecology Studies
- Supramolecular Chemistry and Complexes
- French Urban and Social Studies
- Drug Solubulity and Delivery Systems
- Extraction and Separation Processes
- Enzyme Production and Characterization
- Surfactants and Colloidal Systems
- RNA Interference and Gene Delivery
- Microfluidic and Capillary Electrophoresis Applications
- Fire effects on ecosystems
Laboratoire de Glycochimie, des Antimicrobiens et des Agroressources
2016-2025
Université de Picardie Jules Verne
2016-2025
Conservatoire Botanique National Méditerranéen de Porquerolles
2014-2025
Sorbonne Université
2021-2024
Sorbonne Paris Cité
2011-2024
Centre National de la Recherche Scientifique
2014-2023
Université Sorbonne Paris Nord
2009-2022
Comité Champagne
2022
Stress Environnementaux et Biosurveillance des Milieux Aquatiques
2018
Hospices Civils de Lyon
2009-2018
Abstract The European Alps are highly rich in species, but their future may be threatened by ongoing changes human land use and climate. Here, we reconstructed vegetation, temperature, impact livestock over the past ~12,000 years from Lake Sulsseewli, based on sedimentary ancient plant mammal DNA, pollen, spores, chironomids, microcharcoal. We assembled a highly-complete local DNA reference library (PhyloAlps, 3923 taxa), used this to obtain an exceptionally sed aDNA record of 366 taxa....
Regeneration of ponderosa pine after fire depends on the patterns seed availability and environmental conditions that define safe sites for seedling establishment. A transect approach was applied in 2002 to determine spatial distribution regeneration from unburned burned areas within landscape impacted by Jasper Fire 2000 Black Hills South Dakota (USA). Canopy alone, reflecting availability, at stand level were not correlated with success. However, canopy combination ground explained success...
Abetalipoproteinemia (ABL) is an inherited disease characterized by the defective assembly and secretion of apolipoprotein B–containing lipoproteins caused mutations in microsomal triglyceride transfer protein large subunit (MTP) gene (MTTP). We report here a female patient with unusual clinical biochemical ABL phenotype. She presented severe liver injury, low levels LDL-cholesterol, subnormal vitamin E, but only mild fat malabsorption no retinitis pigmentosa or acanthocytosis. Our objective...
Phenyl- and thienylpyridines were prepared by Pd(0)-catalyzed cross-coupling of 3-pyridylmagnesium chlorides with iodobenzene or iodothiophene at room temperature. Starting from bromo chloro azines diazines, the Ni(0)-catalyzed reaction proved more suitable to allow synthesis pyridylpyridines, pyridylquinolines pyridyldiazines.
The ability to elucidate the structure of organic compounds from their nuclear magnetic resonance (NMR), infrared (IR), and mass spectrometry (MS) spectra is an essential skill, particularly for those engaged in fields synthetic analytical chemistry. Spectral analysis constitutes a fundamental component curriculum all chemistry students, as it requires development critical thinking skills. To engage motivate students structure's elucidation course, gamified learning activity was designed...
We studied 70 unrelated Hunter patients and found a gene alteration in every patient. The molecular heterogeneity was very important. Large rearrangements were identified 14 patients. Forty‐three different mutations the 56 other 31 not previously described. Deletions insertions, splice site associated with severe phenotype as nonsense except Q531X. Only few present several making difficult genotype‐phenotype correlations. Mutation identification allows accurate carrier detection improving...
Abstract Aim Species richness is an important feature of communities that varies along elevational gradients. Different patterns distribution have been described in the literature for various taxonomic groups. This study aims to distinguish between species density and describe, land snails south‐eastern France, altitudinal both at different spatial scales. Location The was conducted on five calcareous mountains France (Etoile, Sainte Baume, Victoire, Ventoux Queyras). Methods Stratified...
RATIONALE Carbohydrates have essential functions in living organisms and cells, but, due to the presence of numerous linkage combinations, substituent sites possible conformations, they are class biomolecules which exhibits huge structural diversity found nature. Thereby, such poor ionization, their deciphering by mass spectrometry is still a very challenging task. METHODS Here, we studied series linear cyclic neutral oligosaccharides using electrospray with collision‐induced dissociation...
This study revisits and optimizes silicon/carbon/poly(acrylic acid) – (PAA) composite anode preparation for lithium-ion batteries.
The semi-synthetic polysaccharide carboxymethylcellulose (CMC) is one of the most studied and effective polymer binders for silicon-based anodes in Li-ion batteries.
Various substituents could be diastereoselectively introduced into the 5-position of pipecolic acid via electrophilic or free-radical-initiated addition to carbon-carbon double bond endocyclic enecarbamates derived from acid. This study allowed diastereoselective synthesis both cis- and trans-5-guanidino pipecolates, which were designed as constrained arginine mimetics whose potential inhibition nitric oxide synthase (NOS) was evaluated with three NOS isoforms.