A5041191656- Palliative Care and End-of-Life Issues
- Venous Thromboembolism Diagnosis and Management
- Family and Patient Care in Intensive Care Units
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Acute Ischemic Stroke Management
- Frailty in Older Adults
- Healthcare Decision-Making and Restraints
- Ethics in medical practice
- Influenza Virus Research Studies
- Cardiac Valve Diseases and Treatments
- Vaccine Coverage and Hesitancy
- COVID-19 and Mental Health
- Nutrition and Health in Aging
- Healthcare professionals’ stress and burnout
- Heart Failure Treatment and Management
- Childhood Cancer Survivors' Quality of Life
- Antiplatelet Therapy and Cardiovascular Diseases
- Healthcare Systems and Practices
- Patient Dignity and Privacy
Centre Hospitalier Universitaire de Besançon
2016-2025
Université de franche-comté
2015-2025
Université de Bourgogne
2017-2025
Université Bourgogne Franche-Comté
2018-2023
German Centre for Cardiovascular Research
2022
Museum of Heilongjiang Province
2021
Hôpital Privé Jean Mermo
2020
Japanese Circulation Society
2019
Society of Thoracic Surgeons
2018
Hôpital Européen
2016
No randomized study has investigated the value of optical coherence tomography (OCT) in optimizing results percutaneous coronary intervention (PCI) for non-ST-segment elevation acute syndromes.We conducted a multicenter, involving 240 patients with syndromes to compare OCT-guided PCI (use OCT pre- and post-PCI; group) fluoroscopy-guided (angiography-guided group). The primary end point was functional result assessed by measure post fractional flow reserve. Secondary points included...
A polypill that includes key medications associated with improved outcomes (aspirin, angiotensin-converting-enzyme [ACE] inhibitor, and statin) has been proposed as a simple approach to the secondary prevention of cardiovascular death complications after myocardial infarction.In this phase 3, randomized, controlled clinical trial, we assigned patients infarction within previous 6 months polypill-based strategy or usual care. The treatment consisted aspirin (100 mg), ramipril (2.5, 5, 10...
The role of extracorporeal membrane oxygenation (ECMO) remains ill defined in pulmonary embolism (PE). We investigated outcomes patients with high-risk PE undergoing ECMO according to initial therapeutic strategy.From 01 January 2014 31 December 2015, 180 from 13 Departments nine centres were retrospectively included. Among those ECMO, we compared characteristics and adjunctive treatment strategy (systemic thrombolysis, surgical embolectomy, or no reperfusion therapy). Primary outcome was...
Coronavirus disease 2019 (COVID-19) may predispose to venous thromboembolism. We determined factors independently associated with computed tomography pulmonary angiography (CTPA)-confirmed embolism (PE) in hospitalised severe COVID-19 patients.Among all (n=349) patients for a university hospital French region high rate of COVID-19, we analysed who underwent CTPA clinical signs (oxygen saturation measured by pulse oximetry ≤93% or breathing ≥30 breaths·min-1) rapid worsening. Multivariable...
Quality of life (QoL) is a multifactorial concept that assesses physical and mental health. We prospectively studied the quality patients undergoing coronary artery bypass graft (CABG) surgery using Short-Form 36-item questionnaire (SF-36) up to 10 years after surgery. Between January 2000 December 2002, all elective isolated CABG in cardiac & thoracic department large university hospital Eastern France underwent initial QoL evaluation with SF-36. The same was mailed every patient annually...
The COVID-19 pandemic has led to significant re-organisation of healthcare delivery in hospitals, with repercussions on all professionals working healthcare. We aimed assess the impact mental health care institutions and identify individual environmental factors influencing risk disorders. From 4 June 22 September 2020, a total 4370 responded an online questionnaire evaluating psychological distress, severity post-traumatic stress symptoms, factors, coping strategies. About 57% suffered from...
Introduction As one means to avoid waste in research investment, involving patients as full partners has become increasingly frequent. There is clearly a low level of investment palliative care research. Following the guidance from James Lind Alliance and UK public consultation (‘Palliative End Life Care Research Priorities Project’), we developed 3-step protocol aimed at prioritising 10 unanswered questions (PC) France, viewpoint patients, volunteers, healthcare professionals family...
The COVID-19 pandemic exposed intensive care unit (ICU) healthcare workers (HCWs) to acute stress (e.g. unpredictability, fear, helplessness) and chronic prolonged crisis with recurring waves). While the psychological impact has been documented, few studies explore overlap of these stressors. One year after pandemic's first peak, we aimed assess psychotraumatic burnout among ICU HCW examine relationship between disorders, perceived workplace This study was conducted in 77 ICUs France June...
Abstract Diet is one of the lifestyle factors that most amenable to intervention, and has a substantial effect on potential for successful aging mitigation risk disease. Good nutrition pillar healthy aging, large body evidence attests benefits Mediterranean diet quality process. The comprises wide range nutrients which, both individually collectively, exert positive effects immunity, in part mediated by gut microbiota. In this article, we review how its beneficial are We certain key...
Ovarian cancer is the fourth most common among women in France, and mainly affects elderly. The primary objective of this study was to compare treatment ovarian according age. All patients with invasive (n = 1151) diagnosed between 1997 2011 Herault Department southern France were included. Demographic data (age, area residence), characteristics (stage, histology, grade) modality (type, period location treatment) analysed. Univariate multivariate logistic regression used by less treated...
Despite the existence of efficacious vaccines, burden vaccine-preventable diseases remains high and potential health benefits paediatric, adolescent adult vaccination are not being achieved due to suboptimal vaccine coverage rates. Based on emerging evidence that pharmacy-based interventions feasible effective, European Interdisciplinary Council for Ageing (EICA) brought together stakeholders from medical pharmacy professions, pharmaceutical industry, patient/ageing organisations authorities...
Abstract Background We investigated the impact of COVID-19 crisis on mental health professionals working in intensive care unit (ICU) according to intensity epidemic France. Methods This cross-sectional survey was conducted 77 French hospitals from April 22 May 13 2020. All ICU frontline healthcare workers were eligible. The primary endpoint health, assessed using 12-item General Health Questionnaire. Sources stress during Perceived Stressors Intensive Care Units (PS-ICU) scale. Epidemic...