A5059353364- Air Quality and Health Impacts
- Maternal Mental Health During Pregnancy and Postpartum
- Birth, Development, and Health
- Climate Change and Health Impacts
- Noise Effects and Management
- Heavy Metal Exposure and Toxicity
- Health, Environment, Cognitive Aging
- Energy and Environment Impacts
- Neonatal Respiratory Health Research
- Child and Adolescent Psychosocial and Emotional Development
- Asthma and respiratory diseases
- Child Abuse and Trauma
- Stress Responses and Cortisol
- Health disparities and outcomes
- Obesity, Physical Activity, Diet
- Infant Development and Preterm Care
- Gestational Diabetes Research and Management
- Child Nutrition and Water Access
- Epigenetics and DNA Methylation
- Pregnancy and preeclampsia studies
- Breastfeeding Practices and Influences
- COVID-19 and Mental Health
- Effects and risks of endocrine disrupting chemicals
- Homelessness and Social Issues
- Health, psychology, and well-being
Icahn School of Medicine at Mount Sinai
2016-2025
Cohort (United Kingdom)
2024-2025
Brown University
2024
Instituto Nacional de Salud Pública
2024
Outcomes Research Consortium
2023
Johns Hopkins University
2023
Faculty of Public Health
2022
University of Georgia
2022
American Lung Association
2022
Boston University
2010-2022
While studies show that ultrafine and fine particles can be translocated from the lungs to central nervous system, possible neurodegenerative effect of air pollution remains largely unexplored. The authors examined relation between black carbon, a marker for traffic particles, cognition among 202 Boston, Massachusetts, children (mean age = 9.7 years (standard deviation, 1.7)) in prospective birth cohort study (1986-2001). Local carbon levels were estimated using validated spatiotemporal...
BackgroundDisproportionate life stress and consequent physiologic alteration (i.e., immune dysregulation) has been proposed as a major pathway linking socioeconomic position, environmental exposures, health disparities. Asthma, for example, disproportionately affects lower-income urban communities, where air pollution social stressors may be elevated.ObjectivesWe aimed to examine the role of exposure violence (ETV), chronic stressor, in altering susceptibility traffic-related asthma...
The influence of particulate air pollution on respiratory health starts in utero. Fetal lung growth and structural development occurs stages; thus, effects postnatal disorders may differ based timing exposure.
Evidence supports an association between maternal exposure to air pollution during pregnancy and children's health outcomes. Recent interest has focused on identifying critical windows of vulnerability. An analysis based a distributed lag model (DLM) can yield estimates window that are different from those regresses the outcome each 3 trimester-average exposures (TAEs). Using simulation study, we assessed bias in obtained using regression approaches: 1) separate models estimate with TAEs; 2)...
Abstract The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort Study (EWC), a collaborative research design comprising 69 cohorts in 31 consortia, was funded by the National Institutes of (NIH) 2016 to improve children’s health United States. EWC harmonizes extant data and collects new using standardized protocol, ECHO-Wide Data Collection Protocol (EWCP). EWCP visits occur at least once per life stage, but frequency timing vary across cohorts. As March 4, 2022,...
DNA methylation is an epigenetic mark that regulates gene expression. Changes in within white blood cells may result from cumulative exposure to environmental metals such as lead. Bone lead, a marker of exposure, therefore better predict than does lead.In this study we compared associations between lead biomarkers and methylation.We measured global participants the Normative Aging Study (all men) who had archived samples. We patella tibia levels by K-X-Ray fluorescence atomic absorption...
The goal was to determine whether cumulative exposure violence in childhood and adolescence contributes disparities self-rated health among a nationally representative sample of US adolescents.
Although a number of studies have documented the relationship between lung function and traffic-related pollution among children, few focused on adult or examined community-based populations.We black carbon (BC), surrogate particles, women in Maternal-Infant Smoking Study East Boston, an urban cohort Massachusetts.We estimated local BC levels using validated spatiotemporal land-use regression model, derived ambient indoor monitor data. We associations percent predicted pulmonary linear...
We examined the association between community violence exposure and childhood asthma risk in a multilevel, multimethod, longitudinal study controlling for individual- neighbourhood-level confounders pathway variables. Analyses included 2,071 children aged 0–9 yrs at enrolment from Project on Human Development Chicago Neighborhoods. Multilevel logistic regression models estimated likelihood of asthma, individual-level (child's age, sex, race/ethnicity, maternal socioeconomic status family...
While there has been considerable attention given to the multitude of maternal factors that contribute perinatal conditions and poor birth outcomes, few studies have aimed understand impact fathers or partners. We examined associations antenatal partner support with psychological variables, smoking behavior, pregnancy outcomes in two socioeconomically distinct prebirth cohorts.Data were from 1764 women recruited an urban-suburban group practice (Project Viva) 877 urban community health...
While adult hypothalamic-pituitary-adrenocortical (HPA) axis functioning is thought to be altered by traumatic experiences, little data exist on the effects of cumulative stress HPA among pregnant women or specific racial and ethnic groups. Individuals may increasingly vulnerable physiological alterations when experiencing multiple stressors. These particularly relevant in urban poor communities where exposure stressors more prevalent. The goal this study was explore social a sample Black (n...
Background Childhood trauma exposure has been associated with deficits in cognitive functioning. The influence of timing on the magnitude and persistence is not well understood. impact early development especially under-investigated. This study examined interpersonal (IPT) first years life childhood Methods Children (N=206) participating a longitudinal birth cohort were assessed prospectively for to IPT (physical or emotional abuse neglect, sexual abuse, witnessing maternal partner violence)...
Abstract Evidence for the intergenerational transmission of posttraumatic stress disorder (PTSD) is documented in literature, although underlying mechanisms are poorly understood. Attachment theory provides a framework elucidating ways which maternal PTSD may increase offspring vulnerability. The current study utilized two independent prospective data sets to test hypotheses that (a) increases probability developing an insecure mother–infant attachment relationship and (b) risk following...
Background: Ambient air pollution may have neurotoxic effects in children. Data examining associations between traffic-related and attention domains remain sparse.Objectives: We examined black carbon (BC), a marker of traffic particles, measures ascertained at 7–14 years age among 174 children birth cohort based the Boston, Massachusetts, area.Methods: estimated BC levels using validated spatial–temporal land-use regression model on residence during children’s lifetime. Children completed...