- Mindfulness and Compassion Interventions
- Pain Mechanisms and Treatments
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Pain Management and Placebo Effect
- Psychosomatic Disorders and Their Treatments
- Musculoskeletal pain and rehabilitation
- Heart Rate Variability and Autonomic Control
- Music Therapy and Health
- Suicide and Self-Harm Studies
- Sleep and Wakefulness Research
- Functional Brain Connectivity Studies
- Traumatic Brain Injury Research
- Child Abuse and Related Trauma
- Migraine and Headache Studies
- COVID-19 and Mental Health
- Child and Adolescent Psychosocial and Emotional Development
- Mind wandering and attention
- Action Observation and Synchronization
- Chemical synthesis and alkaloids
- Psychedelics and Drug Studies
- Perfectionism, Procrastination, Anxiety Studies
- Behavioral Health and Interventions
- Posttraumatic Stress Disorder Research
- Tryptophan and brain disorders
- Digital Mental Health Interventions
University of California, San Diego
2019-2024
University of Florida
2024
La Jolla Alcohol Research
2024
UC San Diego Health System
2023
Johns Hopkins University
2022
University of Maryland, Baltimore
2022
Wake Forest University
2010-2021
University of Puerto Rico at Carolina
2021
Pain Management Institute
2020
KU Leuven
2017
The subjective experience of one's environment is constructed by interactions among sensory, cognitive, and affective processes. For centuries, meditation has been thought to influence such processes enabling a nonevaluative representation sensory events. To better understand how influences the experience, we used arterial spin labeling functional magnetic resonance imaging assess neural mechanisms which mindfulness pain in healthy human participants. After 4 d training, meditating presence...
Mindfulness meditation reduces pain in experimental and clinical settings. However, it remains unknown whether mindfulness engages pain-relieving mechanisms other than those associated with the placebo effect (e.g., conditioning, psychosocial context, beliefs). To determine analgesic of are different from placebo, we randomly assigned 75 healthy, human volunteers to 4 d following: (1) meditation, (2) (3) sham or (4) book-listening control intervention. We assessed intervention efficacy using...
Although long-term meditation has been found to reduce negative mood and cardiovascular variables, the effects of a brief mindfulness intervention when compared sham are relatively unknown. This experiment examined whether 3-day (1-hour total) or would improve variables control group.Eighty-two (82) undergraduate students (34 males, 48 females), with no prior experience, participated in three sessions that involved training either meditation, group. Heart rate, blood pressure, psychologic...
Anxiety is the cognitive state related to inability control emotional responses perceived threats. inversely brain activity associated with regulation of emotions. Mindfulness meditation has been found regulate anxiety. However, mechanisms involved in meditation-related anxiety relief are largely unknown. We employed pulsed arterial spin labeling MRI compare effects distraction form attending breath (ATB; before training) mindfulness (after on across same subjects. Fifteen healthy subjects,...
Migraine is the second leading cause of disability worldwide. Most patients with migraine discontinue medications due to inefficacy or adverse effects. Mindfulness-based stress reduction (MBSR) may provide benefit.To determine if MBSR improves outcomes and affective/cognitive processes compared headache education.This randomized clinical trial vs education included 89 adults who experienced between 4 20 days per month. There was blinding participants (to active comparator group assignments)...
Pain is a highly personal experience that varies substantially among individuals. In search of an anatomical correlate pain sensitivity, we used voxel-based morphometry to investigate the relationship between grey matter density across whole brain and interindividual differences in sensitivity 116 healthy volunteers (62 women, 54 men). Structural magnetic resonance imaging (MRI) psychophysical data from 10 previous functional MRI studies were used. Age, sex, unpleasantness ratings, scanner...
Mindfulness meditation, a cognitive practice premised on sustaining nonjudgmental awareness of arising sensory events, reliably attenuates pain. meditation activates multiple brain regions that contain high expression opioid receptors. However, it is unknown whether mindfulness-meditation-based analgesia mediated by endogenous opioids. The present double-blind, randomized study examined behavioral pain responses in healthy human volunteers during mindfulness and nonmanipulation control...
Abstract Interindividual differences in pain sensitivity vary as a function of interactions between sensory, cognitive–affective, and dispositional factors. Trait mindfulness, characterized the innate capacity to nonreactively sustain attention present moment, is psychological construct that associated with lower clinical outcomes. Yet, neural mechanisms supporting mindfulness are unknown. In an exploratory data analysis obtained during study comparing placebo analgesia, we sought determine...
In social contexts, the dynamic nature of others' emotions places unique demands on attention and emotion regulation. Mindfulness, characterized by heightened receptive moment-to-moment attending, may be well-suited to meet these demands. particular, mindfulness support more effective cognitive control in situations via efficient deployment top-down attention. To test this, a randomized controlled study examined effects training (MT) behavioral neural (event-related potentials [ERPs])...