A5100362716- Escherichia coli research studies
- Genetic diversity and population structure
- Antimicrobial Peptides and Activities
- Immune Response and Inflammation
- Aquaculture disease management and microbiota
- Cell death mechanisms and regulation
- Hedgehog Signaling Pathway Studies
- RNA Interference and Gene Delivery
- Gut microbiota and health
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Insect and Arachnid Ecology and Behavior
- Identification and Quantification in Food
- Real-time simulation and control systems
- Cytokine Signaling Pathways and Interactions
- Epigenetics and DNA Methylation
- Digestive system and related health
- Sensor Technology and Measurement Systems
- Inflammasome and immune disorders
- PARP inhibition in cancer therapy
- Estrogen and related hormone effects
First Affiliated Hospital of Xiamen University
2020-2024
Jimei University
2017
The interactions of pathogens and phagocytes are complex. Our study demonstrated that Aeromonas hydrophila B11 can survive in the macrophagocytes Tilapia mossambica. To explore regulatory processes A. survival macrophagocytes, we used mini-Tn10 transposon mutagenesis system to build a mutant library by mixing Escherichia coli Sm10 (pLOFKm) B11. In total, 102 colonies were detected, 11 them showed reduced macrophagocytes. with most severe phenotype, AM73, was chosen for further research. ORF...
The precise control of cardiomyocyte viability is imperative to combat myocardial ischemia-reperfusion injury (I/R), in which apoptosis and pyroptosis putatively contribute the process. Recent researches indicated that GSDMD involved I/R as an executive protein pyroptosis. However, its effect on other forms cell death unclear. We identified GSDMD-N levels were significantly upregulated myocardium mice. Knockout conferred resistance hearts reperfusion acute phase but aggravated chronic I/R....
Urechis unicinctus is the only Echiurini species distributed in Bohai Gulf of China. The wild populations this have sharply declined China due to overfishing. Over 150 samples from were collected present study, which classified into five according their geographic areas and body colors. genetic diversity population structure these investigated by mitochondiral COI D-loop sequences. haplotype U. based on sequences still high. In addition, evolution rate region could faster than gene...
Histone demethylase JMJD2D (also known as KDM4D) can specifically demethylate H3K9me2/3 to activate its target gene expression. Our previous study has demonstrated that protect intestine from dextran sulfate sodium (DSS)-induced colitis by activating Hedgehog signaling; however, involvement in host defense against enteric attaching and effacing bacterial infection remains unclear. The present was aimed investigate the role of bacteria underlying mechanisms. pathogen Citrobacter rodentium ( C...