A5015277787- Genetic Associations and Epidemiology
- High Altitude and Hypoxia
- Action Observation and Synchronization
- Cardiovascular and Diving-Related Complications
- Motor Control and Adaptation
- Forensic and Genetic Research
- Teaching and Learning Programming
- Behavioral Health and Interventions
- Biochemical Analysis and Sensing Techniques
- Biomedical and Engineering Education
- Genetic diversity and population structure
- Innovative Teaching and Learning Methods
- Race, Genetics, and Society
- Sport Psychology and Performance
- Children's Physical and Motor Development
- Digital Games and Media
- RNA and protein synthesis mechanisms
- Molecular Biology Techniques and Applications
- Nuclear Receptors and Signaling
- Bipolar Disorder and Treatment
- Collaborative Teaching and Inclusion
- Genomics and Rare Diseases
- Problem and Project Based Learning
- Forensic Anthropology and Bioarchaeology Studies
- Education Practices and Evaluation
Medpace (United States)
2021-2024
New York University
2007-2016
York University
2016
Yale University
2010-2015
University of Nevada, Reno
2015
Motor learning occurs over long periods of practice during which motor acuity, the ability to execute actions more accurately, precisely, and in less time, improves. Laboratory-based studies are typically limited a small number participants time frame minutes several hours per participant. There is need assess generalizability theories findings from lab-based on larger samples scales. In addition, laboratory-based use relatively simple tasks unlikely be intrinsically motivated learn,...
Introduction Moderate hypoxia may impact cognitive and sensorimotor performance prior to self-recognized impairments. Therefore, rapid objective assessment tools identify people at risk of impaired function during moderate is needed. Purpose Test the hypothesis that reductions in arterial oxygen saturation normobaric (F i O 2 = 14%) decreases gamified as measured by alterations motor acuity. Methods Following three consecutive days practice, thirty healthy adults (25 ± 5 y, 10 females)...
Abstract Catechol‐ O ‐methyltransferase (genetic locus, COMT ) is a major enzyme involved in catecholamine metabolism and has been associated with numerous psychiatric phenotypes. We studied SNPs haplotypes cocaine‐induced paranoia (CIP) African‐American (AA) European‐American (EA) populations. genotyped 17 across the locus 319 AA pedigrees (848 individuals) 302 EA (707 individuals). Family‐controlled association analyses were conducted using FBAT. found SNP rs737865 to be nominally...
Next‐generation sequencing is widely used to study complex diseases because of its ability identify both common and rare variants without prior single nucleotide polymorphism (SNP) information. Pooled implicated target regions can lower costs allow more samples be analyzed, thus improving statistical power for disease‐associated variant detection. Several methods disease association tests pooled data optimal pooling designs have been developed under certain assumptions the process, example,...
In contrast to traditional professional sports, there are few standardized metrics in esports (competitive multiplayer video games) for assessing a player's skill and ability. We assessed the performance of professional-level players Aim LabTM, first-person shooter training assessment game, with two target-shooting tasks. These tasks differed primarily target size: task large targets provided an incentive be fast but imprecise precise slow. Each motor acuity was measured by characterizing...
Abstract Background Differentiating genetically between populations is valuable for admixture and population stratification detection in understanding history. This easy to achieve major continental populations, but not closely related populations. It has been claimed that a large marker panel necessary reliably distinguish within continent. We investigated whether empirical genetic differentiation could be accomplished efficiently among three Asian (Hmong, Thai, Chinese) using small set of...
Abstract In Thailand, the term Hill Tribe is used to describe populations whose members traditionally practice slash and burn agriculture reside in mountains. These tribes are thought have migrated throughout Asia for up 5,000 years, including migrations through Southern China and/or Southeast Asia. There been continuous southward from into Thailand approximately past thousand years present geographic range of any given tribe straddles multiple political borders. As none these autochthonous...
Competitive esports is a growing worldwide phenomenon now rivaling traditional sports, with over 450 million views and 1 billion US dollars in revenue each year. For comparison, Major League Baseball has 500 $10 revenue, FIFA Soccer 900 $1.6 billion. Despite this significant popularity, much of the world remains unaware — particular, research on for still extremely scarce compared to esports' impact potential.
Detecting population substructure is a critical issue for association studies of health behaviors and other traits. Whether inherent in the or an artifact marker choice, determining aspects population's genetic history as potential sources can aid design future studies. Jewish populations, among which are often conducted, have known migrations. As necessary step understanding structure to conduct valid Israeli Jews, we investigated signatures this quantified facilitate investigations these...
Introduction There is a need for rapid and objective assessment tools to identify people at risk of impaired cognitive function during hypoxia. Purpose To test the hypotheses that performance on gamified tests examining domains executive (Gridshot), working memory (Capacity) spatial tracking (Multitracker) will be reduced normobaric exposure moderate Methods Following three consecutive days practice, twenty-one healthy adults (27 ± 5 y, 9 females) completed five 1-min rounds tablet-based...
Abstract Affective disorders (AFDs) are highly comorbid with substance dependence (SD) and both genetically influenced. However, the specific etiology of comorbidity is not well understood. We genotyped an array 1,350 single nucleotide polymorphisms (SNPs) in or near 130 genes 868 European‐Americans (EAs), including 182 individuals primary AFDs (PAFDs), 214 SD AFD (CAFD), 472 screened controls. NGFB , which encodes nerve growth factor β was represented by 15 SNPs, showed strongest evidence...
Abstract Advancements in technology offer new ways for teachers to inspire and educate students; however, implementation of the learning environment creates unique challenges educators. These require professional development (PD) programs that are capable increasing teacher knowledge about as well teacher’s ability create learner-centered experiences. The LEGO Mindstorms EV3 robotics kit is an example such a technology. offers interactive fun addition helping engage students through...
Abstract Using Robotics as the Technological Foundation for TPACK Framework in K-12 Classrooms In recent years, educators’ increasing reliance on technology has led to development of aconceptual framework teaching known TPACK, which incorporates three keycomponents: technology, pedagogy, and content. The exploits synergisticinteractions among these knowledge domains emphasize use aneffective pedagogical tool creating presenting novel representation that canbe readily accessible students....
Abstract A Robotics-Focused Instructional Framework for Design-Based Research in Middle School Classrooms Design-based research (DBR) is an iterative process which teaching and learning theories arecreated improved with empirical evidence to gain understanding of how why thedesigned works. In this paper, we employ the constructs DBR, context arobotics-based instructional framework, support both student teacher severalways. First, use robotics serves help stimulate interest science,...
Abstract Background GABA transporter-1 (GAT-1; genetic locus SLC6A1 ) is emerging as a novel target for treatment of neuropsychiatric disorders. To understand how population differences might influence strategies pharmacogenetic studies, we identified patterns variation and linkage disequilibrium (LD) in five populations representing three continental groups. Results We resequenced 12.4 kb , including the promoters, exons flanking intronic regions African-American, Thai, Hmong, Finnish,...
She conducted research on human evolutionary and migratory history in South East Asian populations Jewish
Abstract Purpose To compare the effects of purported cognitive enhancing dietary bioactive ingredients on subjective and objective measures motor performance during a first-person shooter video game. Methods Using placebo-controlled crossover design, nine healthy men (23.4±5.7 yr, 178.9±5.8cm, 86.0±17.1kg) completed four 20-minute gaming sessions designed to assess cognitive, motor, perceptual skills via artificial intelligence-driven battery tasks (Aim Lab). Participants ingested either...
ABSTRACT Contrary to traditional professional sports, there are few standardized metrics in esports (competitive multiplayer video games) for assessing a player’s skill and ability. To begin address this, we assessed the performance of professional-level players Aim Lab™, first-person shooter training assessment game, within two separate target-shooting tasks. These tasks differed primarily relative incentive fast imprecise shots versus slow precise shots. Each motor acuity was measured by...
Abstract In summer, 2015, a school of engineering within comprehensive urban university provided 30 teachers with on-campus professional development (PD) and 323 students multi-week direct services using locally-developed robotics smart cities curricula. Goals were to provide hands-on, standards-aligned STEM learning underserved while simultaneously providing embedded PD middle high teachers. Lessons activities for the two curricular tracks have been developed by faculty over past decade...
Hypoxia presents a physiological challenge to the Warfighters during military aviation and subterranean warfare operations by decreasing supply of oxygen brain, which results in reduced cognitive function depending on magnitude duration hypoxic exposure. Moderate exposures, fractions inspired (FiO2) 0.11 0.14, show no effects simple tasks, but complex tasks like working memory may be hindered. Unfortunately, people often cannot recognize their own symptoms hypoxemia, are individualistic at...