- Synthesis and biological activity
- Asthma and respiratory diseases
- Synthesis of Organic Compounds
- Metabolomics and Mass Spectrometry Studies
- Multicomponent Synthesis of Heterocycles
- Pelvic floor disorders treatments
- Advanced Polymer Synthesis and Characterization
- Free Radicals and Antioxidants
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Surgical Treatments
- Inflammatory mediators and NSAID effects
- Nanoparticle-Based Drug Delivery
- Bioactive Compounds and Antitumor Agents
- Phytochemicals and Antioxidant Activities
University of Sannio
2022-2024
Quercetin is a hydrophobic molecule with short blood circulation times and instability. The development of nano-delivery system formulation quercetin may increase its bioavailability, resulting in greater tumor suppressing effects. Triblock ABA type polycaprolactone-polyethylenglycol- polycaprolactone (PCL-PEG-PCL) copolymers have been synthetized using ring-opening polymerization caprolactone from PEG diol. were characterized by nuclear magnetic resonance (NMR), diffusion-ordered NMR...
Purpose: Postoperative pain is a major concern for patients undergoing ultrasound scalpel-assisted hemorrhoidectomy, potentially exacerbated by delayed wound healing. This study aimed to evaluate the impact of an intimate cleansing gel containing chlorhexidine, hyaluronic acid, and other anti-inflammatory agents (Antroclean Fisioderm) on postoperative pain, itching, healing in who had undergone this procedure. Methods: multicenter observational case-control involved cohort consecutive adult...
Oxidative stress and inflammation are two conditions that coexist in many multifactorial diseases the discovery of antioxidants is an attractive approach can simultaneously tackle or more therapeutic targets arachidonic acid cascade.We report simple structural variations on 4-aryl side-arm catechol scaffold significantly influence selectivity against 5-LOX vs 12- 15-LOX. Derivatives 4 a-l were evaluated for their antioxidant activity, using DPPH, ferric ion reducing power (FRAP) methods....