A5101645546- Soybean genetics and cultivation
- Plant nutrient uptake and metabolism
- MicroRNA in disease regulation
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Cancer-related molecular mechanisms research
- GABA and Rice Research
- Kruppel-like factors research
- Food composition and properties
- Heme Oxygenase-1 and Carbon Monoxide
- Insect Resistance and Genetics
- TGF-β signaling in diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Autophagy in Disease and Therapy
- Plant responses to elevated CO2
- Plant Stress Responses and Tolerance
- Histone Deacetylase Inhibitors Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cancer-related gene regulation
- Climate change impacts on agriculture
- Agriculture, Soil, Plant Science
- Nitric Oxide and Endothelin Effects
- Plant Reproductive Biology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Airway Management and Intubation Techniques
Peking University
2024
Peking University International Hospital
2024
Henan Agricultural University
2023
Humboldt-Universität zu Berlin
2023
Freie Universität Berlin
2023
Charité - Universitätsmedizin Berlin
2023
Shanghai University
2012-2020
Wenzhou City People's Hospital
2020
Hebei Normal University
2018
Jiangsu University
2016
Human inducible nitric oxide synthase (hiNOS) gene expression is regulated by transcriptional and posttranscriptional mechanisms. The purpose of this study was to determine whether specific microRNA (miRNA) directly regulate hiNOS expression. Sequence analysis the 496-bp 3′-untranslated region (3′-UTR) revealed five putative miR-939 binding sites. 3′-UTR conferred significant blockade luciferase activity in human A549, HCT8, HeLa cells. also exerted basal cytokine-stimulated repression an...
Zeins are the predominant storage proteins in maize (Zea mays) seeds, while Opaque2 (O2) is a master transcription factor for zein-encoding genes. How activity of O2 regulated and responds to external signals yet largely unknown. Here, we show that E3 ubiquitin ligase ZmRFWD3 interacts with positively regulates its by enhancing nuclear localization. Ubiquitination enhances interaction importin1, α-subunit Importin-1 maize, thus localization ability. We further can be phosphorylated...
TCP (TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR) proteins, a family of plant-specific transcription factors, play important roles in many developmental processes. However, genetic and functional redundancy among class I limits the analysis their biological roles. Here, we identified dominant-negative mutant Arabidopsis thaliana TCP7 named leaf curling-upward (lcu), which exhibits smaller cells shorter hypocotyls than wild type, due to defective endoreplication. A septuple...
Zea mays (maize) Opaque-2 (ZmO2) protein is an important bZIP transcription factor that regulates the expression of major storage proteins (22-kD zeins) and other genes during maize seed development. ZmO2 subject to functional regulation through protein-protein interactions. To unveil potential regulatory network associated with ZmO2, a interaction study was carried out using truncated version (O2-2) as bait in yeast two-hybrid screen cDNA library. A homology Taxilin found have stable...
Carbon monoxide (CO) is a biologically active molecule produced in the body by stress-inducible enzyme, heme oxygenase. We have previously shown that CO suppresses fibrosis murine bleomycin model. To investigate mechanisms which opposes fibrogenesis, we performed gene expression profiling of fibroblasts treated with transforming growth factor-beta(1) and CO. The most highly differentially expressed categories genes included those related to muscular system development small proline-rich...
Several array-based microRNA (miRNA) expression studies independently showed increased of miRNAs hsa-miR-130a-3p, -142-3p, -144-3p, -144-5p, -223-3p, -17-5p, and -30e-5p in gingiva affected by periodontal inflammation. We aimed to determine direct target genes signaling pathways regulated these identify processes relevant gingival inflammatory responses tissue homeostasis. transfected miRNA mimics (mirVana) for each the 7 separately into human primary fibroblasts cultured from 3 different...