A5029324045- Erythropoietin and Anemia Treatment
- Heart Failure Treatment and Management
- Iron Metabolism and Disorders
- Mesenchymal stem cell research
- Blood transfusion and management
- Dialysis and Renal Disease Management
- Potassium and Related Disorders
- Cardiac and Coronary Surgery Techniques
- Diabetes Treatment and Management
- Vitamin D Research Studies
- Tissue Engineering and Regenerative Medicine
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiovascular Issues in Pregnancy
- Lymphatic System and Diseases
- Angiogenesis and VEGF in Cancer
- Congenital heart defects research
- Medication Adherence and Compliance
Treant Zorggroep
2024
University Medical Center Groningen
2008-2015
Medisch Centrum Leeuwarden
2015
University of Groningen
2013
Abstract The paracrine properties of human amniotic membrane-derived mesenchymal stromal cells (hAMCs) have not been fully elucidated. goal the present study was to elucidate whether hAMCs can exert beneficial effects on infarcted rat hearts, in particular through cardioprotection and angiogenesis. Moreover, we aimed identify putative active mediators. were isolated, expanded, characterized. In vitro, conditioned medium from hAMC (hAMC-CM) exhibited cytoprotective proangiogenic properties....
Abstract Aims Despite clear guideline recommendations for initiating four drug classes in all patients with heart failure (HF) reduced ejection fraction (HFrEF) and the availability of rapid titration schemes, information on real‐world implementation lags behind. Closely following 2021 ESC HF guidelines 2023 focused update, TITRATE‐HF study started to prospectively investigate use, sequencing, guideline‐directed medical therapy (GDMT) patients, including identification barriers. Methods...
<h3>Objective</h3> To investigate the association between sustained postoperative anaemia and outcome after coronary artery bypass graft (CABG) surgery. <h3>Design</h3> Retrospective analysis of IMAGINE trial, which tested effect ACE inhibitor quinapril on cardiovascular events CABG. <h3>Setting</h3> Thoracic surgery clinic/outpatient department. <h3>Patients</h3> 2553 stable patients with left ventricular ejection fraction >40% 2–7 days scheduled <h3>Interventions</h3> Randomisation to...
Anaemia in heart failure (HF) is associated with a poor prognosis. Although inflammation assumed to be an important cause of anaemia, the association between anaemia and inflammatory markers patients HF has not been well established.Data from multicentre randomised clinical trial, which were eligible if they >18 years age admitted for (New York Heart Association II-IV), used. In subset 326 patients, haemoglobin (Hb), haematocrit, high sensitivity C-reactive protein (hsCRP), interleukin-(IL)...
In conclusion, phrenic nerve stimulation due to LV lead dislodgement can mimic an abdominal aortic aneurysm.Pacemaker rotation leading displacement was previously described by Bayliss et al. as Twiddler's syndrome [1] and has a reported frequency of 0.07-7 % [2].It named after patients who twiddled with the device resulting in dislodgement.However, also occur spontaneously.It causes failure pace result brachial plexus, vagus nerve, pectoral muscle, or [2].Twiddler's is more frequent older...
Background: mesenchymal stem cells of fetal origin (F-MSC) can be isolated from the amniotic membrane human placenta. We have data showing that F-MSC exert remarkable cardioprotective and proangiogenic effects through paracrine mechanisms. However, complete nature scope soluble mediators cardioprotection not been investigated yet. Methods: were term Human dermal fibroblasts used as control population. Total RNA proteins extracted cultured (N=10) (n=10) after 48 hrs serum deprivation....