Melissa A. Elafros

ORCID: 0000-0002-4511-201X
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About
Contact & Profiles
Research Areas
  • HIV Research and Treatment
  • Epilepsy research and treatment
  • Pain Mechanisms and Treatments
  • Botulinum Toxin and Related Neurological Disorders
  • HIV/AIDS Research and Interventions
  • Pharmacological Effects and Toxicity Studies
  • Cardiac Arrhythmias and Treatments
  • HIV/AIDS drug development and treatment
  • Atrial Fibrillation Management and Outcomes
  • Bacterial Infections and Vaccines
  • Parkinson's Disease Mechanisms and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Neurology and Historical Studies
  • HIV-related health complications and treatments
  • Bariatric Surgery and Outcomes
  • Hereditary Neurological Disorders
  • Racial and Ethnic Identity Research
  • Mental Health Treatment and Access
  • Genetic Neurodegenerative Diseases
  • Cytomegalovirus and herpesvirus research
  • Diet and metabolism studies
  • Musculoskeletal pain and rehabilitation
  • Pharmacology and Obesity Treatment
  • Spine and Intervertebral Disc Pathology
  • Diabetic Foot Ulcer Assessment and Management

University of Michigan
2021-2025

Johns Hopkins University
2016-2025

Baldwin Wallace University
2025

Women's College Hospital
2025

Indiana University Bloomington
2025

Michigan State University
2013-2024

Hurley Medical Center
2024

Northwestern University
2024

University of Zambia
2014-2024

University of Rochester
2014-2024

'Intersectional stigma' is a concept that has emerged to characterize the convergence of multiple stigmatized identities within person or group, and address their joint effects on health wellbeing. While enquiry into intersections race, class, gender serves as historical theoretical basis for intersectional stigma, there little consensus how best analyze design interventions this complex phenomenon. The purpose paper highlight existing stigma literature, identify gaps in our methods studying...

10.1176/appi.focus.25023006 article EN FOCUS The Journal of Lifelong Learning in Psychiatry 2025-01-01

Distal symmetric polyneuropathy (DSP) is a disabling, often painful condition associated with falls and reduced quality of life. Non-Hispanic Black people low income are underrepresented in existing DSP studies; therefore, it unknown whether data accurately reflect the prevalence, risk factors, burden disease these populations.

10.1212/wnl.0000000000209390 article EN Neurology 2024-05-08

Epilepsy-associated stigma contributes substantially to the social, medical, and economic burden of disease for people with epilepsy (PWE), but little is known about its impact on caregivers PWE. To better understand experienced by PWE, factors that influence caregiver stigma, effect a caregiver's psychologic well being, we interviewed 100 children in Zambia. Questions assessed maternal knowledge, attitudes, practices related epilepsy, mother's proxy report child psychiatric morbidity. Of...

10.1093/inthealth/iht028 article EN International Health 2013-11-08

This cross-sectional study compares the diagnostic testing for patients with peripheral neuropathy of from 1998 to 2007 in 2019.

10.1001/jamaneurol.2025.0001 article EN JAMA Neurology 2025-03-03

Background— Transformation from persistent to paroxysmal atrial fibrillation (AF) after ablation suggests modification of the underlying substrate. We examined nature initial arrhythmia recurrence in patients with nonparoxysmal AF undergoing antral pulmonary vein isolation and nonpulmonary trigger correlated type long-term efficacy last procedure. Methods Results— Three hundred seventeen consecutive (n=200) long-standing (n=117) first were included. was defined as early (≤6 weeks) or late...

10.1161/circep.116.004239 article EN Circulation Arrhythmia and Electrophysiology 2016-10-26

Voltage Differences With Multielectrode Mapping Introduction Bipolar voltage criteria to delineate left atrial (LA) scar have been derived using point‐by‐point (PBP) contact electroanatomical mapping. It remains unclear how PBP‐derived LA correlates with multielectrode fast automated mapping (ME‐FAM) scar. We aimed correlate and bipolar voltages from maps created PBP versus ME‐FAM. Methods Results In consecutive patients undergoing repeat AF ablation, 2 separate were ME‐FAM during sinus...

10.1111/jce.13151 article EN Journal of Cardiovascular Electrophysiology 2016-12-20

This article provides an up-to-date review of the diagnosis and management most common neuropathies that occur in patients with diabetes.

10.1212/con.0000000000001291 article EN CONTINUUM Lifelong Learning in Neurology 2023-10-01

Lumbar puncture (LP) is a safe, standard procedure essential in the investigation of variety neurological disorders. However, many regions, LP uptake and performance are low, even when it strongly indicated. We sought to understand patient, caregiver, healthcare worker perspectives rural Zambia. conducted cross-sectional survey adult patients, caregivers pediatric nurses, doctors, clinical officers at two hospitals Southern Province The consisted questions on self-reported knowledge, an...

10.4269/ajtmh.24-0749 article EN American Journal of Tropical Medicine and Hygiene 2025-05-20

To identify the etiology of new-onset seizure in HIV-infected Zambian adults and risk factors for recurrence.A prospective cohort study enrolling with within 2 weeks index obtained clinical, laboratory, neuroimaging data to determine etiology. Participants were followed recurrence. Risk mortality examined as rates unexpectedly high.Eighty-one patients CSF analysis enrolled a median 306 days (interquartile range 61-636). Most (91%) at WHO stage III/IV 66 (81%) had pre-seizure Karnofsky score...

10.1212/wnl.0000000000003538 article EN Neurology 2016-12-24

Whether successful catheter ablation for atrial fibrillation (AF) reduces risk of cerebrovascular events (CVEs) remains controversial and whether oral anticoagulation therapy (OAT) can be safely discontinued in patients rendered free AF recurrences unknown. We evaluated OAT use patterns examined long-term rates CVEs (stroke/TIA) major bleeding episodes (MBEs) with nonparoxysmal treated ablation.Four hundred (200 persistent, 200 longstanding persistent; mean age 60.3 ± 9.7 years, 82% male)...

10.1111/jce.13476 article EN Journal of Cardiovascular Electrophysiology 2018-03-07

The aim of the study was to describe patient characteristics and outcomes among HIV-positive adults presenting a Zambian tertiary care hospital with new-onset seizures.From July 2011 June 2013, seizures known or probable diagnosis HIV infection were screened for cohort study. Demographic clinical data obtained, including information on engagement in services in-patient mortality. Analyses conducted identify associated poor death.A total 320 351 HIV-positive, 268 experiencing seizures. Of...

10.1111/hiv.12283 article EN HIV Medicine 2015-07-22

To describe acute EEG findings in HIV-infected adults with new-onset seizure, assess baseline clinical characteristics associated abnormalities, and evaluate the relationship between abnormalities recurrent seizure.

10.1212/wnl.0000000000001411 article EN Neurology 2015-03-05

ABSTRACT. In much of sub-Saharan Africa, lumbar punctures (LPs) are performed less frequently than indicated. This is often attributed to patient/family refusal; however, other factors have not been systematically evaluated. We investigated predictors LP performance for a prospective cohort people with HIV and new-onset seizures at three hospitals in Zambia. enrolled 257 participants, including 184 (72%) adults 144 (56%) urban participants. LPs were 65% 33% children, 69% 38% rural...

10.4269/ajtmh.21-0091 article EN American Journal of Tropical Medicine and Hygiene 2021-08-09
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