- Clinical Laboratory Practices and Quality Control
- Healthcare cost, quality, practices
- Meta-analysis and systematic reviews
- Cervical Cancer and HPV Research
- Health Systems, Economic Evaluations, Quality of Life
- Digital Imaging for Blood Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Colorectal Cancer Screening and Detection
- Vitamin D Research Studies
- AI in cancer detection
- Lipoproteins and Cardiovascular Health
- Global Cancer Incidence and Screening
- Chronic Disease Management Strategies
- Animal Behavior and Reproduction
- Diabetes Management and Education
- Plant and animal studies
- Artificial Intelligence in Healthcare and Education
- Animal Vocal Communication and Behavior
- Chronic Lymphocytic Leukemia Research
- Diabetes Management and Research
- T-cell and B-cell Immunology
- Vitamin C and Antioxidants Research
- Primary Care and Health Outcomes
- Bacterial Identification and Susceptibility Testing
- Innovations in Medical Education
University of Calgary
2016-2025
Alberta Health Services
2016-2025
Health Sciences Centre
2015-2023
Calgary Laboratory Services
2013-2022
York University
2021
South Health Campus
2021
Alberta Medical Association
2017
Red Deer Regional Hospital
2017
Dalhousie University
1996-2016
Western University
2000-2016
Although current guidelines recommend measuring lipid levels in a fasting state, recent studies suggest that nonfasting profiles change minimally response to food intake and may be superior predicting adverse cardiovascular outcomes. The objective of this study was investigate the association between times levels.Cross-sectional examination laboratory data, including duration (in hours) results, performed over 6-month period 2011 large community-based cohort. Data were obtained from Calgary...
There are 5 major histotypes of ovarian carcinomas. Diagnostic typing criteria have evolved over time, and past cohorts may be misclassified by current standards. Our objective was to reclassify the recently assembled Canadian Ovarian Experimental Unified Resource Alberta Tumor Type using immunohistochemical (IHC) biomarkers develop an IHC algorithm for carcinoma histotyping. A total 1626 samples from were subjected a reclassification comparing original with predicted histotype. Histotype...
The systematic review of clinical research papers is a labor-intensive and time-consuming process that often involves the screening thousands titles abstracts. accuracy efficiency this are critical for quality subsequent health care decisions. Traditional methods rely heavily on human reviewers, requiring significant investment time resources.
SARS-CoV-2 has been detected in wastewater and its abundance correlated with community COVID-19 cases, hospitalizations deaths. We sought to use wastewater-based detection of assess the epidemiology hospitals. Between August December 2020, twice-weekly samples from three tertiary-care hospitals (totaling > 2100 dedicated inpatient beds) were collected. Hospital-1 Hospital-2 could be captured a single sampling point whereas Hospital-3 required separate monitoring sites. Wastewater...
Increased type I error resulting from multiple statistical comparisons remains a common problem in the scientific literature. This may result reporting and promulgation of spurious findings. One approach to this is correct groups P-values for “family-wide significance” using Bonferroni correction or less conservative Bonferroni-Holm “false discovery rate” with Benjamini-Hochberg correction. Although several solutions are available performing through commercially software there no widely easy...
Abstract Background Parents of infants in neonatal intensive care units (NICUs) are often unintentionally marginalized pursuit optimal clinical care. Family Integrated Care (FICare) was developed to support families as part their infants’ team level III NICUs. We adapted the model for II NICUs Alberta, Canada, and evaluated whether new Alberta FICare™ decreased hospital length stay (LOS) preterm without concomitant increases readmissions emergency department visits. Methods In this pragmatic...
Pathology informatics has evolved to varying levels around the world. The history of pathology in different countries is a tale with many dimensions. At first glance, it familiar story individuals solving problems that arise their clinical practice enhance efficiency, better manage (e.g., digitize) laboratory information, as well exploit emerging information technologies. Under surface, however, lie powerful resource, regulatory, and societal forces helped shape our discipline into what...
To identify inappropriate repeats of six common laboratory tests in a population sample patients, using highly specific criteria based only on repeat time and test value.We used informatics database to conduct retrospective cohort study 103,000 patients the city Calgary with an index 2010 uniform follow-up 1 year. We examined (cholesterol, hemoglobin A1c, thyroid-stimulating hormone, vitamin B12, D, ferritin) consensus-based or easily justified for solely value.The percentages repeated at 3,...
Chronic lymphocytic leukemia (CLL) is the most common type of blood cancer in Canadian adults. CLL cells are abnormal lymphocytes, which tend to be slightly larger than normal resting lymphocytes and have a condensed appearance their chromatin. There low number related works on this disease. This paper presents method segment into two parts: nucleus, cytoplasm using watershed algorithm optimal thresholding. The goal work reducing over under segmentation error by suppressing 1% local minima....
The incidence rate of acute myeloid leukemia (AML) was determined in the Calgary Metropolitan Area, a major Canadian city.Data from all patients diagnosed with AML between January 1, 2011 and December 31, 2015 were retrieved single, centralized cancer cytogenetics laboratory for bone marrow samples, sole diagnostic facility its kind Southern Alberta.The calculated 2.79 cases per 100,000 person-years median age 60, slightly lower than previously published data. age-standardized Canada 3.46...
Aims To determine and quantify the prevalence of patient, provider system level barriers to achieving diabetes care goals; examine whether were different for people with poor glycemic control (HbA1c ≥ 10%; 86 mmol/mol) compared fair (7 <8%; 53–64 mmol/mol). Methods We administered a survey by telephone community-dwelling patients diabetes, patient-reported facilitators care. responses in individuals HbA1c 10% (86 against those between 7–8% (53–64 examined associations group care, adjusting...
Although there is an accepted benchmark for adenoma detection rate (ADR) in average risk screening colonoscopy, a ADR or the associated quality indicator, adenomas per colonoscopy (APC), colonoscopies performed positive fecal immunochemical test (FIT+) has not been established. The purpose of this study was to propose methods establishing and APC FIT+ patients.In historical cohort study, we included 15,329 patients aged 50-74 years who underwent at Alberta Health Services' Colon Cancer...
Leukocyte differentials are an important component of clinical care. Morphologic assessment peripheral blood smears (PBS) may be required to accurately classify leukocytes. However, manual microscopy is labor intensive. The CellaVision DM96 automated system that acquires digital images leukocytes on PBS, pre-classifies the cell type, and displays them screen for a Technologist or Pathologist approve reclassify. Our study compares results with microscopy.Three hundred fifty-nine PBS were...
Abstract Background Every year, about 15 million of the world’s infants are born preterm (before 37 weeks gestation). In Alberta, birth rate was 8.7% in 2015, second highest among Canadian provinces. Approximately 20% before 32 gestation (early preterm), and require care a Level III neonatal intensive unit (NICU); 80% moderate (32 zero days [32 0/7 ] to 33 6/7 weeks) late (34 36 weeks), II NICU. Preterm experiences NICU disrupt early parent-infant relationships induce parental psychosocial...
Introduction: Delta checks use two specimen test results taken in succession order to detect result changes greater than expected physiological variation. One of the most common and serious errors detected by delta is mix-up errors. The positive negative predictive values for detecting errors, however, are largely unknown. Materials Methods: We addressed this question first constructing a stochastic dynamic model using repeat five analytes from approximately 8000 inpatients Calgary, Alberta,...