Murat Kaan Durgut

ORCID: 0000-0002-4582-8536
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Research Areas
  • Animal Virus Infections Studies
  • SARS-CoV-2 and COVID-19 Research
  • Animal health and immunology
  • Viral gastroenteritis research and epidemiology
  • COVID-19 Clinical Research Studies
  • Parasitic Infections and Diagnostics
  • Acute Kidney Injury Research
  • Pancreatitis Pathology and Treatment
  • Cardiovascular Conditions and Treatments
  • Virus-based gene therapy research
  • Coccidia and coccidiosis research
  • Viral Infections and Vectors
  • Reproductive Physiology in Livestock
  • Osteomyelitis and Bone Disorders Research
  • Renal function and acid-base balance
  • Lipid metabolism and disorders
  • Veterinary Medicine and Surgery
  • Hemoglobinopathies and Related Disorders
  • Clostridium difficile and Clostridium perfringens research
  • Veterinary Equine Medical Research
  • Electrolyte and hormonal disorders
  • Dermatological diseases and infestations
  • Platelet Disorders and Treatments
  • Dialysis and Renal Disease Management
  • Virology and Viral Diseases

Selçuk University
2020-2024

Abstract The present study aimed to investigate endothelial glycocalyx (eGCx) damage in cats with feline hemotropic mycoplasmosis caused by Mycoplasma haemofelis using selected biomarkers and determine the diagnostic prognostic significance of these biomarkers. included 25 10 healthy cats. Clinical examination, blood gas analysis, complete count, biochemical analysis were performed. Hemotropic diagnosed microscopic examination molecularly confirmed PCR targeting 16s rRNA gene. To evaluate...

10.1038/s41598-024-62359-7 article EN cc-by Scientific Reports 2024-06-05

To evaluate the usefulness of intestinal biomarkers in determining presence epithelial damage neonatal calves with diarrhea caused by 4 etiologic agents.

10.2460/ajvr.81.2.139 article EN American Journal of Veterinary Research 2020-01-27

Abstract Background Approaches to the evaluation of pulmonary arterial hypertension (PAH) in premature calves by using lung‐specific epithelial and endothelial biomarkers are needed. Objective To investigate PAH with without respiratory distress syndrome (RDS) determine prognostic value these markers calves. Animals Fifty RDS, 20 non‐RDS calves, 10 healthy term Methods Hypoxia, hypercapnia, tachypnea were considered criteria for RDS. Arterial blood gases (PaO 2 , PaCO oxygen saturation [SO...

10.1111/jvim.16217 article EN cc-by Journal of Veterinary Internal Medicine 2021-07-05

To investigate intestinal injury, repair and vasculitis biomarkers that may illuminate the progression and/or pathogenesis of feline infectious peritonitis (FIP) or enteric coronavirus (FECV) infection.A total 40 cats with effusive FIP (30 abdominal effusion, AE group; 10 thoracic TE group) asymptomatic but FECV positive (FECV group), all were confirmed by reverse transcription polymerase chain reaction either in faeces effusion samples. Physical examinations tests performed. Trefoil...

10.1002/vms3.1299 article EN cc-by Veterinary Medicine and Science 2023-10-24

Abstract Background Displaced abomasum (DA) is one of the most important metabolic disorders dairy cattle. In DA, ischaemic damage may occur as a result impaired perfusion due to abomasal displacement, which in gastrointestinal mucosal damage. Objective Investigation tissue cattle with right displacement (RDA) and left (LDA) using intestinal‐related biomarkers. Methods Forty‐eight DA (24 LDA, 24 RDA) 15 healthy Holstein cows were enrolled between March 2021 July 2022. Serum biomarkers...

10.1002/vms3.1292 article EN cc-by Veterinary Medicine and Science 2023-09-30

Canine parvoviral enteritis (PVE) is one of the most common diseases in young dogs. A range and inflammatory conditions can cause endothelial glycocalyx (eGCX) disruption, therefore, this study aimed to determine presence eGCX damage dogs with PVE using serum biomarkers eGCX, evaluate their prognostic importance among survivor non-survivor Twenty diagnosed 10 healthy both sexes, mixed-breed, under 6 months age were included study. Clinical examination, blood gas analysis, complete cell...

10.4067/s0719-81322020000300095 article EN cc-by-nc Austral journal of veterinary sciences 2020-09-01

Mitochondrial biogenesis (MB) induction has recently emerged as potential therapeutic approaches in kidney pathology and the mitochondria-targeted therapies should be investigated to improve treatment of animals with diseases. This study aimed investigate effects MB sildenafil citrate on cGMP/NO pathway, glomerular filtration, reduction damage fibrosis (TGF-β/SMAD pathway) cats acute chronic disease (ACKD). Thirty-three were divided into non-azotemic (healthy) group (n:8) ACKD (n:25),...

10.1186/s12917-024-04345-9 article EN cc-by-nc-nd BMC Veterinary Research 2024-10-31

The purpose of the present study was to establish development acute kidney injury (AKI) and evaluate usefulness kidney-specific biomarkers in diagnosing AKI premature calves with respiratory distress syndrome (RDS). Ten-term healthy 70 RDS were enrolled. Clinical examination, blood gases, chemical analysis performed at admission 72 h. Serum concentrations urea nitrogen (BUN), creatinine (Cre), phosphorus (P), cystatin-C (Cys-C), neutrophil gelatinase-associated lipocalin (NGAL), uromodulin...

10.3390/ani13020232 article EN cc-by Animals 2023-01-08

This study aimed to assess the usefulness of injury biomarkers specific intestines in identifying presence and degree intestinal epithelial damage coccidiosis-infected calves. Forty calves various breeds sexes, aged 21 days 60 days, were used study. Of these, 30 experimental group, 10 healthy control. The McMaster Oocyte counting technique was diagnose Eimeria confirm clinical coccidiosis. Cases with signs more than 5,000 oocysts gram feces included All had blood samples drawn at 0 th hours...

10.5398/tasj.2023.46.2.221 article EN cc-by-sa Tropical Animal Science Journal 2023-05-25

This clinical report describes a 1-year-old Golden Retriever dog weighing 24 kg that developed gastroenteritis as result of the unprescribed and random use syrup Hedera helix extract, which is for human only. Diagnosis was made after ruling out other factors could cause gastroenteritis. An improvement in findings observed supportive treatment. It already widely recognized triterpene saponins, biological active compounds helix, dogs it considered at high doses, may severe symptoms will...

10.19052/mv.vol1.iss42.11 article EN cc-by-nc-nd Revista de Medicina Veterinaria 2021-05-12

13 year-old male dog with complaints of fever, loss appetite, stagnation as well respiratory signs such purulent nasal and eye discharge, cough neurologic including apathy, ataxia, quadriplegia, muscular atrophy myoclonus which admitted to the Animal Hospital Faculty Veterinary Medicine Selcuk University. “Old encephalitis” was determined by clinical, laboratory examinations rapid distemper test. Clinical findings revealed hyperthermia, tachypnea tachycardia. Intravenous 0.9% NaCl 5%...

10.30607/kvj.610338 article EN Kocatepe Veterinary Journal 2020-05-02

Abstract Feline coronavirus (FCoV) infections occur commonly in cats, with entrocyte and monocyte-macrophage tropism. Most FCoV-infected cats remain asymp tomatic, but up to 10% develop fatal feline infectious peritonitis (FIP). This study aims investigate the diagnostic utility of clinical laboratory examinations including serum effusion AGP levels either symptomatic effusive FIP or asymptomatic enteric (FECV). The included 40 10 FECV infection. group was divided into two subgroups:...

10.2478/acve-2023-0003 article EN cc-by Acta veterinaria 2023-03-01

Hypoglycemia is a condition associated with neonatal diarrhea in calves, leading to increased mortality and neurological clinical signs. The aim of the present study was determine development brain damage hypoglycemic calves diagnostic prognostic significance these biomarkers. Ten healthy 50 were included study. Clinical examination, blood gases complete count performed at admission. Blood serum calcium-binding protein B (S100B), neuron-specific enolase (NSE), glial fibrillary acidic (GFAP),...

10.3389/fvets.2023.1240846 article EN cc-by Frontiers in Veterinary Science 2023-10-31

BackgroundFeline coronavirus (FCoV) infection is very common in cats and one of its pathotype, feline enteric (FECV), usually only causes mild gastroenteritis while up to 10% FCoV infections result the fatal disease, infectious peritonitis (FIP). Although asymptomatic thought be mainly confined intestines, healthy with FECV may have systemic infection, albeit lower viral loads than FIP.ObjectiveInvestigation certain intestinal damage, repair vasculitis biomarkers illuminate pathogenesis...

10.2139/ssrn.4117416 article EN SSRN Electronic Journal 2022-01-01

The aim of the presented study was to evaluate some blood gas, hemogram, and biochemical parameters in cats with hemoplasmosis. Ten healthy fifteen hemoplasmosis were enrolled study. 7 mL sample taken once from all included into tubes without anticoagulant. Blood complete count, analyzes performed samples. While pH HCO3 levels significantly lower than cats, lactate BE higher (p< 0.05). WBC, MON, GRA RDW found be while RBC, HCT, Hb, PLT AST, TBIL, DBIL, P, TRI, LDH, TP, CPK subjects, ALB...

10.30607/kvj.1144267 article EN Kocatepe Veterinary Journal 2022-10-23

Bağırsaklar, besinlerin sindirimi ve emilimi ile birlikte canlıları çevresel tehditlere karşı koruyan bir immünolojik organ özelliğine sahiptir. Enterokolitis, ince bağırsakların yangısı olan enteritis kolonun kolitisi içeren sindirim kanalının olarak tanımlanmaktadır. Bakteriyel, viral, protozoal, fungal, paraziter etkenlere diğer nedenlere bağlı oluşan bu durum önemli derecede su, besin mineral kayıpları seyredebilmektedir. Enterokolitislerin seyri sırasında bağırsaklarda gelişen villus...

10.5336/vetsci.2020-79135 article TR Turkiye Klinikleri Journal of Veterinary Sciences 2022-01-01

Amaç: Bu çalışmada kriptosporidiozis ile doğal olarak enfekte olmuş neonatal buzağıların tedavisinde gamitromisinin klinik etkinliğinin

10.15312/eurasianjvetsci.2021.325 article TR Eurasian journal of veterinary sciences 2021-03-03
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