A5031750440- Peroxisome Proliferator-Activated Receptors
- Animal health and immunology
- Neonatal Respiratory Health Research
- Viral gastroenteritis research and epidemiology
- Clostridium difficile and Clostridium perfringens research
- Medicinal Plant Pharmacodynamics Research
- Natural Products and Biological Research
- Nuclear Receptors and Signaling
- Sesame and Sesamin Research
- Acute Kidney Injury Research
- Abdominal Trauma and Injuries
- Pulmonary Hypertension Research and Treatments
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Metabolism, Diabetes, and Cancer
- Hops Chemistry and Applications
- Renal function and acid-base balance
- Primate Behavior and Ecology
- Natural Antidiabetic Agents Studies
- Pharmacological Effects and Toxicity Studies
- Advanced Glycation End Products research
- Natural product bioactivities and synthesis
- Animal Nutrition and Physiology
- Neurological Disease Mechanisms and Treatments
- Diet, Metabolism, and Disease
Dicle University
2024
Harran University
2024
Selçuk University
2021-2024
Abstract Background Approaches to the evaluation of pulmonary arterial hypertension (PAH) in premature calves by using lung‐specific epithelial and endothelial biomarkers are needed. Objective To investigate PAH with without respiratory distress syndrome (RDS) determine prognostic value these markers calves. Animals Fifty RDS, 20 non‐RDS calves, 10 healthy term Methods Hypoxia, hypercapnia, tachypnea were considered criteria for RDS. Arterial blood gases (PaO 2 , PaCO oxygen saturation [SO...
Çalışmanın amacı farelerde deneysel olarak oluşturulan tip 2 diyabetes mellitus (T2DM)’de sesamin, saponin, sesamin + tahin, çöven ektsraktı ve tahin uygulamalarının aspartat aminotransfraz (AST), alanin aminotransferaz (ALT), kan üre nitrojen (BUN) kreatinin düzeylerine etkisini belirlemektir. Araştırmada 92 adet Swiss albino erkek fare kullanıldı. Sekiz sağlıklı kontrol (SK) grubu için ayrıldıktan sonra diğer hayvanlarda yüksek yağlı besleme streptozotosin (STZ) uygulaması yapılarak T2DM...
Abstract Objectives The aim of this study was to determine the single and combined antidiabetic activity side effects retinoid X receptor agonist bexarotene thioredoxin-interacting protein inhibitor peroxisome proliferator-activated γ AMP-activated kinase activator icariin. Methods rats were grouped as healthy (control), diabetes, diabetes + (20 mg/kg), icariin (60 (10 mg/kg) (30 low-dose combination high-dose groups. Key findings Icariin treatment led a significant reduction in glucose...
The aim of the study was to compare levels postprandial glucose, oral glucose tolerance test, and malondialdehyde parameters in 3 different experimental type 2 diabetic models induced rats. In study, 18 Wistar albino rats were divided into groups. high-fat diet streptozotocin (35 mg/kg, SC) administered first group, water containing 20% fructose second nicotinamide (110 IP) (60 third group. Oral analyzes rat performed they euthanized at 70th days. level higher 1st 3rd model groups than 2nd...
The purpose of the present study was to establish development acute kidney injury (AKI) and evaluate usefulness kidney-specific biomarkers in diagnosing AKI premature calves with respiratory distress syndrome (RDS). Ten-term healthy 70 RDS were enrolled. Clinical examination, blood gases, chemical analysis performed at admission 72 h. Serum concentrations urea nitrogen (BUN), creatinine (Cre), phosphorus (P), cystatin-C (Cys-C), neutrophil gelatinase-associated lipocalin (NGAL), uromodulin...
Neonatal calf diarrhea (NCD) is one of the most important concerns in cattle production.Escherichia coli bacterial agent NCD.Although vaccination and antibiotic treatment are common NCD, high antigenic diversity E. increase resistance cause difficulties control.The study aimed to investigate rate diarrhea, isolate an NCD strain, determine antimicrobial resistance, find out about some surface antigens.Fecal samples (n=115) were analyzed pathogenic strains with nine mixed infections; sixty-one...
Neonatal calf diarrhea (NCD) is one of the most important concerns in cattle production.Escherichia coli bacterial agent NCD.Although vaccination and antibiotic treatment are common NCD, high antigenic diversity E. increase resistance cause difficulties control.The study aimed to investigate rate diarrhea, isolate an NCD strain, determine antimicrobial resistance, find out about some surface antigens.Fecal samples (n=115) were analyzed pathogenic strains with nine mixed infections; sixty-one...
Objective Type 2 diabetes mellitus (T2DM), a chronic metabolic disorder affecting over 400 million people globally, is increasingly recognized for its detrimental impact on the central nervous system. T2DM linked to neurodegenerative diseases like Alzheimer's and vascular dementia. This study investigates neuroprotective effects of bexarotene icariin in rat model, focusing brain-derived neurotrophic factor (BDNF), glial fibrillary acidic protein (GFAP), neurofilament-light chain (NfL)...
This study was aimed to determine the pharmacokinetics of antisecretory-acting racecadotril, used in treatment diarrhea humans and dogs, following oral administration both neonatal calves with healthy infectious diarrhea. The carried out on a total 24 Holstein (2-20 days), which 6 were 18 Calves divided into 3 groups according agent (Escherichia coli, Cryptosporidium parvum, rotavirus/coronavirus). Racecadotril administered orally at 2.5 mg/kg dose calves. plasma concentrations racecadotril...
This study aimed to determine the effect of administration oral vitamins A and E at different doses on plasma brain concentrations ivermectin in mice. The was carried out 174 Swiss Albino male mice aged 8-10 weeks. After leaving six for method validation, remaining were randomly divided into seven groups with equal numbers animals. Mice received (0.2 mg/kg, subcutaneous) alone combination low (vitamin A: 4000 IU/kg; vitamin E: 35 mg/kg) high 30 000 500 E. measured using high-performance...