A5092023922- Peroxisome Proliferator-Activated Receptors
- Natural Antidiabetic Agents Studies
- Neurological Disease Mechanisms and Treatments
- Metabolism, Diabetes, and Cancer
- Pharmacological Effects and Toxicity Studies
- Medicinal Plant Pharmacodynamics Research
- Diet, Metabolism, and Disease
- Primate Behavior and Ecology
- Natural product bioactivities and synthesis
- Antimicrobial Peptides and Activities
- Aquaculture disease management and microbiota
- Invertebrate Immune Response Mechanisms
- Nuclear Receptors and Signaling
- Animal Nutrition and Physiology
Dicle University
2024
Harran University
2024
Selçuk University
2023-2024
Abstract Background Fish skin mucus contains innate immune factors and acts as the first line of physical or chemical defense against pathogens. Objective The primary aim this study was to determine antiviral activity sea bream (SBr), rainbow trout (RT), bass (SBa) fish herpes simplex virus (HSV)‐1. In addition, it aimed associate possible with antimicrobial peptides (AMPs) such cathelicidin, hepcidin, galectin 2, C10ORF99, whose levels were determined in mucus. Methods oxidative/antioxidant...
Abstract Objectives The aim of this study was to determine the single and combined antidiabetic activity side effects retinoid X receptor agonist bexarotene thioredoxin-interacting protein inhibitor peroxisome proliferator-activated γ AMP-activated kinase activator icariin. Methods rats were grouped as healthy (control), diabetes, diabetes + (20 mg/kg), icariin (60 (10 mg/kg) (30 low-dose combination high-dose groups. Key findings Icariin treatment led a significant reduction in glucose...
The aim of the study was to compare levels postprandial glucose, oral glucose tolerance test, and malondialdehyde parameters in 3 different experimental type 2 diabetic models induced rats. In study, 18 Wistar albino rats were divided into groups. high-fat diet streptozotocin (35 mg/kg, SC) administered first group, water containing 20% fructose second nicotinamide (110 IP) (60 third group. Oral analyzes rat performed they euthanized at 70th days. level higher 1st 3rd model groups than 2nd...
Neonatal calf diarrhea (NCD) is one of the most important concerns in cattle production.Escherichia coli bacterial agent NCD.Although vaccination and antibiotic treatment are common NCD, high antigenic diversity E. increase resistance cause difficulties control.The study aimed to investigate rate diarrhea, isolate an NCD strain, determine antimicrobial resistance, find out about some surface antigens.Fecal samples (n=115) were analyzed pathogenic strains with nine mixed infections; sixty-one...
Objective Type 2 diabetes mellitus (T2DM), a chronic metabolic disorder affecting over 400 million people globally, is increasingly recognized for its detrimental impact on the central nervous system. T2DM linked to neurodegenerative diseases like Alzheimer's and vascular dementia. This study investigates neuroprotective effects of bexarotene icariin in rat model, focusing brain-derived neurotrophic factor (BDNF), glial fibrillary acidic protein (GFAP), neurofilament-light chain (NfL)...
This study aimed to determine the effect of administration oral vitamins A and E at different doses on plasma brain concentrations ivermectin in mice. The was carried out 174 Swiss Albino male mice aged 8-10 weeks. After leaving six for method validation, remaining were randomly divided into seven groups with equal numbers animals. Mice received (0.2 mg/kg, subcutaneous) alone combination low (vitamin A: 4000 IU/kg; vitamin E: 35 mg/kg) high 30 000 500 E. measured using high-performance...