A5022813179- Smoking Behavior and Cessation
- Air Quality and Health Impacts
- Advanced Chemical Sensor Technologies
- Metabolomics and Mass Spectrometry Studies
- Carcinogens and Genotoxicity Assessment
- Human Health and Disease
- Noise Effects and Management
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer Research and Treatment
- Nutrition, Genetics, and Disease
- Analytical Chemistry and Chromatography
- Biological Research and Disease Studies
- Air Quality Monitoring and Forecasting
- Nutritional Studies and Diet
- Genomics, phytochemicals, and oxidative stress
Institut Pasteur de Lille
2021-2024
Université de Lille
2020-2024
Centre Hospitalier Universitaire de Lille
2021-2024
IMPact de l'Environnement Chimique sur la Santé humaine
2018-2024
Metabolite identification in untargeted metabolomics is complex, with the risk of false positive annotations. This work aims to use machine learning successively predict retention time (Rt) and collision cross-section (CCS) an open-access database accelerate interpretation metabolomic results. Standards metabolites were tested using liquid chromatography coupled high-resolution mass spectrometry. In CCSBase QSRR predictor models, experimental results used generate predicted CCS Rt Human...
Electronic cigarettes (e-cig) and heated tobacco products (HTP) are often used as smoking cessation aids, while the harm reduction effects of these alternatives to still subject controversial debate, in particular regarding their carcinogenic potential. The objective this study is compare e-cig, HTP conventional cigarette emissions on generation oxidative stress genetic epigenetic lesions human bronchial epithelial BEAS-2B cells. Our results show that were less cytotoxic than e-cig not...
Smoking is an established risk factor for various pathologies including lung cancer. Electronic cigarettes (e-cigs) and heated tobacco products (HTPs) have appeared on the market in recent years, but their safety or, conversely, toxicity has not yet been demonstrated. This study aimed to compare metabolome of human epithelial cells exposed emissions e-cigs, HTPs, or 3R4F order highlight potential early markers toxicity. BEAS-2B were cultured at air–liquid interface short-term from e-cigs set...