- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- X-ray Diffraction in Crystallography
- Retinal Development and Disorders
- Crystallization and Solubility Studies
- Wood Treatment and Properties
- Surface Roughness and Optical Measurements
- Meningioma and schwannoma management
- Neurological disorders and treatments
- Material Properties and Processing
- Forest, Soil, and Plant Ecology in China
- Food Drying and Modeling
- Identification and Quantification in Food
- Advanced Cellulose Research Studies
- Bacillus and Francisella bacterial research
- Probiotics and Fermented Foods
- Photochromic and Fluorescence Chemistry
- Gut microbiota and health
- Trigeminal Neuralgia and Treatments
- Congenital heart defects research
- Sulfur Compounds in Biology
- Sepsis Diagnosis and Treatment
- Environmental Chemistry and Analysis
- Zebrafish Biomedical Research Applications
- Lignin and Wood Chemistry
University of Pittsburgh
2022
Korea Institute of Toxicology
2019-2021
Chungnam National University
2016-2020
Chung-Ang University
2015-2017
Korea University
2013-2015
Sungkyunkwan University
2014
Ewha Womans University
2007-2008
Although innate color preference of motile organisms may provide clues to behavioral biases, it has remained a longstanding question.In this study, we investigated zebrafish larvae.A cross maze with different sleeves around each arm was used for the test (R; red, G; green, B; blue, Y; yellow).The findings showed that 5 dpf larvae preferred blue over other colors (B > R G Y).To study recognition further, tyrosinase mutants were generated using CRISPR/Cas9 system.As model oculocutaneous...
Acrylamide is a commonly used industrial chemical that known to be neurotoxic mammals. However, its developmental toxicity rarely assessed in mammalian models because of the cost and complexity involved. We zebrafish assess neurotoxicity, behavioral acrylamide. At 6 h post fertilization, embryos were exposed four concentrations acrylamide (10, 30, 100, or 300 mg/L) medium for 114 h. caused characterized by yolk retention, scoliosis, swim bladder deficiency, curvature body. also impaired...
Objective : Aneurysms are very rarely encountered in the distal posterior inferior cerebellar artery (PICA).The authors experienced 5 cases with a PICA aneurysm among 368 of intracranial aneurysms during period from January 2003 to 2008.Here, describe their clinical and surgical experiences include review relevant literature.Methods Using radiologic findings charts, we retrospectively reviewed results treated 2008.Results The current five were composed four 'Good' one case 'Fair'.No...
본 연구에서는 UPLC를 이용하여 시네프린과 n-메틸티라민을 단시간에 동시 분석할 수 있는 새로운 방법을 개발한 후 시험법에 대한 평가를 수행하였으며, 확립된 방법으로 21종의 오렌지 및 감귤 주스와 5종의 감귤에서 정량 분석을 실시하였다. 분석한 결과 HPLC에 비해 분석시간을 3배 이상 단축하여 15분 이내에 분석하였고, 각 성분의 감도가 월등히 높아져 UPLC로 분석 시 시간적, 경제적인 면에서 효율적으로 두 분석이 가능하였다. UPLC 검출한계는 n-메틸티라민이 각각 0.02 mg/L과 0.01 mg/L, 정량한계는 0.06 0.04 mg/L로 설정되었다. n-메틸티라민의 회수율은 96.4%와 100.9%로 분석되었다. 분석법으로 시중에서 판매하는 감귤의 과육과 과피에서 모두 과육보다 7-12배 높은 함량을 나타내었다. 시판 주스를 시네프린 함량이 14.61-120.39 mg/kg으로 분석되었으며, n-메틸티라민은 불검출에서 3.34 주스 중 약간 수준의 샘플이...
Abstract Escherichia coli possesses four phenotypically distinct systems of acid resistance (AR). AR is an important characteristic E. , enabling the organism to survive acidic environments. In this study, a wild‐type strain, K12, and two foodborne isolates were tested for AR. 2, 3, 4 required presence glutamate, arginine, or lysine, respectively, during challenge tests at pH 2.0 after adaptation HCl organic acids (pH 5.0). characteristics found be similar those strain. Nonetheless, survival...
Polyhexamethylene guanidine-phosphate (PHMG-P), a guanidine-based cationic antimicrobial polymer, is an effective biocide, potent even at low concentrations. Due to its resilient bactericidal properties, it has been used extensively in consumer products. It was safely until use humidifiers led catastrophic event South Korea. Epidemiological studies have linked the of PHMG-P as humidifier disinfectant pulmonary fibrosis. However, little known about harmful impacts other than Thus, we applied...
Formation and the surface roughness of paper are important factors to determine quality paper. is determined by an extent fiber distribution non-uniformity. which decides three-dimensional structure If has poorly formation, there a wide change in local basis weight, thickness physical chemical properties due non-uniformity bonding. also affects strength, opacity printability The indicates degree height deviation direction. stylus can be used measure profile directly. SMD (mean absolute from...
Abstract A type of vertical alignment (VA) LCD shows a decrease in off‐axis image quality. Although it has been improved using super patterned VA (S‐PVA), its aperture ratio decreases. This letters reports the application temporal division method (TDM) which is introduced to improve both quality and ratio.
The purpose of this study is to understand the current status and cause distribution odor substances in Yeosu National Industrial Complex its surrounding areas. Samples were analyzed by collecting 90 samples at dawn, daytime night from a total 15 points, 9 points management area, 2 boundary 4 affected area. analysis items include 5 meteorological factors, complex odor, 22 types designated odors other Volatile Organic Compounds (VOCs). At MA3 (Fig. 1) point strict emission allowance standard...
후각기관은 주변 환경의 다양한 화학물질을 감지하는 기관으로 생존, 종족번식에서 감정에 이르기까지 다양하고 중요한 역할을 하고 있다. 유전적, 환경적 등 요소에 의해 후각장애가 발생할 수 있으며, 일시적인 경우에는 약물치료 등으로 회복될 있지만, 신경세포에 문제가 생긴 영구적인 손상의 경우는 치료가 어렵다. 따라서, 신경세포의 사멸을 억제하거나 재생을 유도하는 치료제의 개발이 필요하다. 본 연구에서는 후각신경세포 특이적으로 GFP 형광단백질을 발현하는 형질전환동물을 제작하여 생체 내 후각신경세포를 관찰하고자 하였다. 또한, 처리하여 손상을 인위적으로 유도할 있는 방법을 고안하였고, 후각신경세포의 손상 및 재생 과정을 실시간으로 모니터링하였다. 연구를 통해 확립된 모니터링 시스템은 향후 메커니즘 연구 치료제 개발에 유용하게 사용될 것으로 기대된다. The olfactory system is an important model for the study of neuronal...
Currently, widely used methods of measuring surface properties paper are air leakage- type such as the Bekk smoothness method and Bendtsen roughness method. Measurements in this air-leakage may have advantages for purpose comparing differences between samples, but they limitation understanding variation within one sample. To measure characteristics directly, profile can be analyzed by hill valley using stylus tip. Based on measured data, it is fractal geometry theory. It known that not a...