- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Ear Surgery and Otitis Media
- Bacterial Infections and Vaccines
- Respiratory and Cough-Related Research
- Ion Channels and Receptors
- Acoustic Wave Resonator Technologies
- Pneumocystis jirovecii pneumonia detection and treatment
- Facial Nerve Paralysis Treatment and Research
- Influenza Virus Research Studies
- Asthma and respiratory diseases
- Trigeminal Neuralgia and Treatments
Wakayama Medical University
2021-2024
Tokyo Women's Medical University Adachi Medical Center
2021
Streptococcus pneumoniae , one of the most common commensal pathogens among children, is spread by close contact in daycare centers or within a family. Host innate immune responses and bacterial virulence factors promote pneumococcal transmission. However, investigations into effects environmental on transmission have been limited. Passive smoking, great concern for children’s health, has reported to exacerbate diseases. Here, we describe effect cigarette smoke exposure an infant mouse model...
Transient receptor potential (TRP) channels, neuronal stimulations widely known to be associated with thermal responses, pain induction, and osmoregulation, have been shown in recent studies underlying mechanisms inflammatory responses. The role of TRP channels on milieu during bacterial infections has demonstrated. It may vary among types channels/pathogens, however, it is not how function pneumococcal infections. Streptococcus pneumoniae can cause severe such as pneumonia, bacteremia,...
We established an infant mouse model for colonization and transmission by nonencapsulated Streptococcus pneumoniae (NESp) strains to gain important information about its virulence among children. Invasive pneumococcal diseases have decreased dramatically since the worldwide introduction of capsular polysaccharide vaccines. Increasing prevalence nonvaccine serotypes, including NESp, has been highlighted as a challenge in treatment strategy, but NESp is not well understood. Protective...
Idiopathic bilateral facial nerve palsy is a rare condition and presents diagnostic prognostic challenge. Specifically, when nerves are damaged, it difficult to predict the prognosis. We showcase usefulness of contrast-enhanced magnetic resonance imaging (MRI) by providing information about localization severity degeneration nerve. A 70-year-old Japanese man presented with simultaneous House-Brackmann Grade VI on both sides. Contrast-enhanced MRI revealed intensity enhancement intratemporal...