A5015983470- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Insect symbiosis and bacterial influences
- Dengue and Mosquito Control Research
- Zoonotic diseases and public health
- Malaria Research and Control
- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Viral Infections and Outbreaks Research
University of Bern
2018-2024
Medical University of Lodz
2017
The mosquito-borne Japanese encephalitis virus (JEV) causes severe central nervous system diseases and cycles between Culex mosquitoes different vertebrates. For JEV some other flaviviruses, oronasal transmission is described, but the mode of infection unknown. Using nasal mucosal tissue explants primary porcine epithelial cells (NEC) at air-liquid interface (ALI) macrophages as ex vivo in vitro models, we determined that epithelium could represent route entry exit for pigs. Porcine NEC ALI...
Several mosquito-borne Flaviviruses such as Japanese encephalitis virus (JEV), West Nile (WNV), Dengue Virus (DENV) and Zika (ZIKV) can cause severe clinical disease. Being zoonotic, infect a wide variety of terrestrial vertebrates, which dependent the virus-host interactions, enhance ongoing epidemics maintain in environment for prolonged periods. Targeted species vary from amphibians, birds to various mammals, on virus. For many flaviviruses spectrum targeted is incompletely understood,...
Abstract Japanese encephalitis virus (JEV) is a zoonotic mosquito-transmitted Flavivirus circulating in birds and pigs. In humans, JEV can cause severe viral with high mortality. Considering that vector-free direct transmission was observed pigs, introduction into an immunologically naïve pig population could result series of transmissions disrupting the alternating host cycling between vertebrates mosquitoes. To assess potential consequences such realistic scenario, we passaged ten times...
Japanese encephalitis virus (JEV) is a zoonotic mosquito-transmitted Flavivirus circulating in birds and pigs. In humans, JEV can cause severe viral with high mortality. Considering that vector-free direct transmission was observed experimentally infected pigs, introduction into an immunologically naïve pig population could result series of transmissions disrupting the alternating host cycling between vertebrates mosquitoes. To assess potential consequences such realistic scenario, we...