A5052155719- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Nosocomial Infections in ICU
- Streptococcal Infections and Treatments
- Pneumonia and Respiratory Infections
- Clostridium difficile and Clostridium perfringens research
- Bacterial biofilms and quorum sensing
- Bacterial Identification and Susceptibility Testing
- Neonatal and Maternal Infections
- Sepsis Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Antifungal resistance and susceptibility
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotics Pharmacokinetics and Efficacy
- Social and Demographic Issues in Germany
- demographic modeling and climate adaptation
- Inhalation and Respiratory Drug Delivery
- Syphilis Diagnosis and Treatment
- Diphtheria, Corynebacterium, and Tetanus
- Fecal contamination and water quality
- Pediatric health and respiratory diseases
- Patient Satisfaction in Healthcare
- Nail Diseases and Treatments
- Phytochemistry and biological activities of Ficus species
- Respiratory Support and Mechanisms
Lithuanian University of Health Sciences
2011-2024
Hospital of Lithuanian University of Health Sciences Kaunas Clinics
2017-2020
Kauno kolegija Higher Education Institution
2012
Kaunas University of Technology
2008-2009
Background and objectives: High mortality healthcare costs area associated with ventilator-associated pneumonia (VAP) due to Acinetobacter baumannii (A. baumannii). The data concerning the link between multidrug-resistance of A. strains outcomes remains controversial. Therefore, we aimed identify relation risk factors for drug resistance profiles baumannii) independent predictors in-hospital mortality. Methods: A retrospective ongoing cohort study 60 patients that were treated VAP...
Building the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen One Health antimicrobial resistance (AMR) surveillance approach.
The aim of our study was to determine the prevalence Pseudomonas aeruginosa bacteremia, risk factors, and outcome patients treated at Hospital Kaunas University Medicine. Material methods. All hospitalized with blood culture positive for during 5-year period were included. A retrospective data analysis performed evaluate patients’ factors mortality caused by P. bacteremia. Results. total 47 (58.8%) bacteremia episodes occurred in an intensive care unit (ICU). primary source identified 50...
The aim of this study was to determine the characteristics carbapenem-resistant Pseudomonas aeruginosa (P. aeruginosa) strains and 5-year changes in resistance a tertiary university hospital. Material Methods. included 90 101 randomly selected P. serotyped 2003 2008, respectively. standardized disk diffusion test E-test were used antibiotics. considered have high-level if minimum inhibitory concentration (MIC) for imipenem or meropenem >32 μg/mL. To identify serogroups, sera containing...
Introduction: Acinetobacter spp. are important pathogens increasingly reported as the cause of outbreaks nosocomial infections. The aim our study was to identify risk factors and assess their influence on outcomes in patients with infections caused by carbapenem-resistant Methods: A retrospective data analysis performed evaluate mortality Methods used for statistical were Student's t-test, Chi-square test, multivariate analysis; p < 0.05 considered statistically significant. Results: total...
Background and objective: Acinetobacter baumannii (A. baumannii) is an important nosocomial pathogen that not only possesses intrinsic resistance to many classes of antibiotics, but also capable rapidly developing antimicrobial during treatment. The aim this study was determine the characteristics A. strains β-lactams other tested evaluate associations between phenotypes changes in antibiotic over 5 years by comparing periods 2016–2017 2020–2021. Materials methods: A total 233 were isolated...
Clostridioides difficile (C. difficile) is a predominant nosocomial infection, and guidelines for improving diagnosis treatment were published in 2017. We conducted single-center, retrospective 10-year cohort study of patients with primary C. infectious disease (CDID) at the largest referral Lithuanian university hospital, aiming to evaluate clinical laboratory characteristics CDID their association outcomes, as well implication concordance current Clinical Practice Guidelines. The enrolled...
Background and objective: Serologic testing is a useful additional method for the diagnosis of COVID-19. It also used population-based seroepidemiological studies. The objective study was to determine SARS-CoV-2 seroprevalence in healthcare workers Kaunas hospitals compare two methods specific antibody testing. Materials Methods: A total 432 were enrolled this study. Each participant filled questionnaire including questions about their demographics, contact with suspected or confirmed...
Abstract The Two Weeks in the World research project has resulted a dataset of 3087 clinically relevant bacterial genomes with pertaining metadata, collected from 59 diagnostic units 35 countries around world during 2020. A relational database is available metadata and summary data selected bioinformatic analysis, such as species prediction identification acquired resistance genes.
Abstract Pseudomonas aeruginosa (P. aeruginosa) is one of the most important opportunistic pathogens. The pathogenicity P. has been associated with multiple bacterial virulence factors. aim this study was to evaluate association between strains obtained from various clinical samples and resistance antibiotics factors, such as serum bactericidal activity biofilm formation. This included 121 isolated samples; 65 were carbapenem-resistant, 56 carbapenem-sensitive. Carbapenem-resistant more...
The aim was to estimate changes in the resistance rates of Pseudomonas aeruginosa (P. aeruginosa) strains isolated from patients treated intensive care units largest university hospital. Materials and Methods. Isolates were identified with Phoenix ID system (Becton Dickinson, USA). minimum inhibitory concentration (MIC) ceftazidime, ciprofloxacin, amikacin determined by E-test evaluated following recommendations Clinical Laboratory Standards Institute. Results. In 2003, proportion P....
Background and objective: Acinetobacter baumannii (A. baumannii) is an important nosocomial pathogen that possesses not only intrinsic resistance to many classes of antibiotics, but also capable rapidly develop antimicrobial during treatment. The aim our study was determine the production different types &beta;-lactamases (AmpC, ESBL, KPC) in A. strains, evaluate its association with resistance, identify changes these characteristics after 5 years. Materials methods: A total 233 strains...
Candidemia is becoming more actual because of better survival even critically ill patients, wide use antimicrobials, and increased numbers invasive procedures manipulations. Diagnosis candidemia remains complicated, costs treatment mortality rates are increasing. Objective. To evaluate the pathogens candidemia, risk factors their influence on outcome. Material methods. Data 41 patients with positive blood culture for Candida spp., who were treated in intensive care units at Hospital Kaunas...
Background and objective: Acinetobacter baumannii (A. baumannii) is an important nosocomial pathogen that possesses not only intrinsic resistance to many classes of antibiotics, but also capable rapidly develop antimicrobial during treatment. The aim our study was determine the production different types β-lactamases (AmpC, ESBL, KPC) in A. strains, evaluate its association with resistance, identify changes these characteristics after 5 years. Materials methods: A total 233 strains were...
Aim of the study. To determine associations between source infection and antibiotic resistance in patients with Pseudomonas aeruginosa bacteremia. Material methods. A retrospective analysis 50 bacteremia was carried out. If sepsis suspected, blood culture incubated an automatic system BACTEC 9240. Then bacteria were identified, their estimated by disc diffusion method. strains resistant to three or more antibiotics, they considered as multidrug-resistant.Results. The origin confirmed 33...