Donat R. Spahn

ORCID: 0000-0002-4782-183X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Blood transfusion and management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Trauma and Emergency Care Studies
  • Blood donation and transfusion practices
  • Hemodynamic Monitoring and Therapy
  • Healthcare Technology and Patient Monitoring
  • Cardiac Arrest and Resuscitation
  • Erythropoietin and Anemia Treatment
  • Venous Thromboembolism Diagnosis and Management
  • Hemoglobin structure and function
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Hemoglobinopathies and Related Disorders
  • Patient Safety and Medication Errors
  • Iron Metabolism and Disorders
  • Sepsis Diagnosis and Treatment
  • Abdominal Trauma and Injuries
  • Hemostasis and retained surgical items
  • Mechanical Circulatory Support Devices
  • Simulation-Based Education in Healthcare
  • Heart Failure Treatment and Management
  • Cardiac Imaging and Diagnostics
  • Team Dynamics and Performance
  • Airway Management and Intubation Techniques
  • Healthcare Operations and Scheduling Optimization

University Hospital of Zurich
2015-2024

University of Zurich
2014-2024

Society for the Advancement of Blood Management
2011-2022

Committee on Publication Ethics
2020

Papworth Hospital
2020

Universidad de Málaga
2020

University Hospital Frankfurt
2020

Goethe University Frankfurt
2020

Duke University
1992-2020

Novo Nordisk (Switzerland)
2019

Severe trauma continues to represent a global public health issue and mortality morbidity in patients remains substantial. A number of initiatives have aimed provide guidance on the management patients. This document focuses major bleeding coagulopathy following encourages adaptation guiding principles each local situation implementation within institution.

10.1186/s13054-016-1265-x article EN cc-by Critical Care 2016-04-12

Severe traumatic injury continues to present challenges healthcare systems around the world, and post-traumatic bleeding remains a leading cause of potentially preventable death among injured patients. Now in its fifth edition, this document aims provide guidance on management major coagulopathy following encourages adaptation guiding principles described here individual institutional circumstances resources. The pan-European, multidisciplinary Task Force for Advanced Bleeding Care Trauma...

10.1186/s13054-019-2347-3 article EN cc-by Critical Care 2019-03-27

Evidence-based recommendations are needed to guide the acute management of bleeding trauma patient, which when implemented may improve patient outcomes. The multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed 2005 with aim developing a guideline following severe injury. This document presents an updated version published by group 2007. Recommendations were formulated using nominal process, Grading Assessment, Development and Evaluation (GRADE) hierarchy evidence...

10.1186/cc8943 article EN cc-by Critical Care 2010-01-01

Blood utilization has long been suspected to consume more health care resources than previously reported. Incomplete accounting for blood costs the potential misdirect programmatic decision making by systems. Determining cost of supplying patients with transfusions requires an in-depth examination complex array activities surrounding transfuse.To accurately determine in a surgical population from system perspective, activity-based costing (ABC) model was constructed. Tasks and resource...

10.1111/j.1537-2995.2009.02518.x article EN Transfusion 2009-12-09

Abstract Introduction Evidence-based recommendations can be made with respect to many aspects of the acute management bleeding trauma patient, which when implemented may lead improved patient outcomes. Methods The multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed 2005 aim developing guidelines following severe injury. Recommendations were formulated using a nominal group process and GRADE (Grading Assessment, Development, Evaluation) hierarchy evidence based on...

10.1186/cc5686 article EN cc-by Critical Care 2007-02-13

Background Preconditioning by volatile anesthetics is a promising therapeutic strategy to render myocardial tissue resistant perioperative ischemia. It was hypothesized that sevoflurane preconditioning would decrease postoperative release of brain natriuretic peptide, biochemical marker for dysfunction. In addition, several variables associated with the protective effects were evaluated. Methods Seventy-two patients scheduled coronary artery bypass graft surgery under cardioplegic arrest...

10.1097/00000542-200306000-00004 article EN Anesthesiology 2003-06-01

Background: Perioperative anemia has been associated with increased risk of red blood cell transfusion and morbidity mortality after surgery. The optimal approach to the diagnosis management perioperative is not fully established. Objective: To develop consensus recommendations for in surgical patients. Methods: An international expert panel reviewed current evidence developed using modified RAND Delphi methodology. Results: recommends that all patients except those undergoing minor...

10.1097/sla.0000000000005721 article EN cc-by-nc-nd Annals of Surgery 2022-09-21

Summary Remimazolam, a short‐acting benzodiazepine, may be used for induction and maintenance of total intravenous anaesthesia, but its role in the management patients with multiple comorbidities remains unclear. In this phase 3 randomised controlled trial, we compared anaesthetic efficacy incidence postinduction hypotension during anaesthesia remimazolam vs. propofol. A 365 (ASA physical status or 4) scheduled elective surgery were assigned randomly to receive (n = 270) propofol 95)....

10.1111/anae.16205 article EN cc-by-nc-nd Anaesthesia 2024-01-14
Coming Soon ...