A5010460550- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Biology and Fertility
- Cancer Treatment and Pharmacology
- Advanced Breast Cancer Therapies
- Breast Cancer Treatment Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Breastfeeding Practices and Influences
- Cancer, Lipids, and Metabolism
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Maternal and Perinatal Health Interventions
- Global Maternal and Child Health
- Health Literacy and Information Accessibility
- Angiogenesis and VEGF in Cancer
- Pituitary Gland Disorders and Treatments
- Prostate Cancer Treatment and Research
- Cancer Immunotherapy and Biomarkers
- Multiple and Secondary Primary Cancers
- Genetic factors in colorectal cancer
- Ovarian cancer diagnosis and treatment
- Neutropenia and Cancer Infections
- Hepatitis C virus research
- Immune cells in cancer
Azienda Ospedaliera Santa Maria Degli Angeli
2013-2020
IRCCS Materno Infantile Burlo Garofolo
2013
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2007
University of Messina
2005
Presidio Ospedaliero
2005
Background Caesarean delivery (CD) rates are commonly used as an indicator of quality in obstetric care and risk adjustment evaluation is recommended to assess inter-institutional variations. The aim this study was evaluate whether the Ten Group classification system (TGCS) can be case-mix adjustment. Methods Standardized data on 15,255 deliveries from 11 different regional centers were prospectively collected. Crude Risk Ratios CDs calculated for each center. Two multiple logistic...
There are approximately 1,000,000 pregnant women at high risk for obstetric complications per year, more than half of whom require hospitalization.The aim this study was to determine the relation between online health information seeking and anxiety levels in a sample hospitalized woman with pregnancy-related complications.A 105 northern Italy, all an complication diagnosis, completed different questionnaires: Use Internet Health-information (UIH) questionnaire about use internet, EuroQOL 5...
The aim of the study was to identify which groups women contribute interinstitutional variation caesarean delivery (CD) rates and are reasons for this variation. In regard, 15,726 deliveries from 11 regional centers were evaluated using 10-group classification system. Standardized indications CD in each group used. Spearman’s correlation coefficient used calculate (1) relationship between institutional relative sizes/CD ten groups/centers; (2) groups/centers. Overall correlated with both...
15036 Background: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the folate metabolism pathway. Two common genetic polymorphisms (C677T and A1298C) are associated with reduced MTHFR activity. The aim of our study was to analyze distribution C677T A1298C gene colorectal cancer (CRC) patients (pts), evaluate their role as predictive markers 5-FU toxicity adjuvant chemotherapy. Methods: Genomic DNA isolated from peripheral blood lymphocytes 23 pts, using Puregene Purification...
An infertile couple with a hepatitis C (HCV) RNA-positive male came to our attention. We were not able perform an assisted reproduction technology (ART) procedure ejaculated spermatozoa free of HCV RNA using gradient centrifugation and swim up, due retrograde ejaculation severe factor. ICSI testicular was the most rational therapeutic approach. The informed about lack adequate data on safety this risks accepted by couple. Testicular sperm aspiration combined (TESA-ICSI) performed. After...
Newer agents and combinations are needed in order to improve current results ovarian cancer treatment. Gemcitabine is a novel agent that has shown consistent activity as single the treatment of platinum-resistant favorable toxicity profile. Because its clinical preclinical synergism with platinum analogs, gemcitabine been combined carboplatin convincing approach platinum-sensitive recurrent patients. Further combination other agents, including paclitaxel, also feasible actively studied...
e14621 Background: primary and acquired resistance cause treatment failure to several agents. Recently it is emerging the role of immune surveillance in control tumor progression. The tolerance correlates with disease progression FOXP3+ regulatory T cells (Tregs) myeloid-derived suppressor (MDSC) play a relevant immunosuppression. Cyclophosphamide (C) Fluorouracil (FU) seems reduce these cell populations. Methods: Objective: safety, feasibility, pain control, activity impact on system...
790 Background: Aim of the study was to assess efficacy and safety combination gemcitabine (GEM) liposomal doxorubicin (PLD) in patients (pts) with measurable recurrence/metastasis from breast cancer (BC). Methods: A phase II a two-stage design planned an early stopping case <10 responses 27 pts. If >9 were observed accrual increased up 81 pts regimen considered active if at least 30 among 81. This provided 80% chance correctly classifying treatment as inactive true probability response...
e12005 Background: Elderly breast cancer patients have an increased risk of toxicity from chemotherapy, especially anthracycline-based regimens. Pegylated liposomal doxorubicin (PLD) has shown a better tolerability profile also in combination with gemcitabine (GEM), as evidenced several phase II trials. The aim this study is to retrospectively evaluate the safety and activity chemo-naïve or pre-treated elderly advanced cancer. Methods: From January 2006 March 2008, 39 (pts) age ≥ 65...
<sec> <title>BACKGROUND</title> There are approximately 1,000,000 pregnant women at high risk for obstetric complications per year, more than half of whom require hospitalization. </sec> <title>OBJECTIVE</title> The aim this study was to determine the relation between online health information seeking and anxiety levels in a sample hospitalized woman with pregnancy-related complications. <title>METHODS</title> A 105 northern Italy, all an complication diagnosis, completed different...