A5010378662- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Rheumatoid Arthritis Research and Therapies
- Esophageal Cancer Research and Treatment
- Chronic Lymphocytic Leukemia Research
- Inflammatory mediators and NSAID effects
- Nutrition and Health in Aging
- Pneumocystis jirovecii pneumonia detection and treatment
- Parathyroid Disorders and Treatments
- Antifungal resistance and susceptibility
- Magnesium in Health and Disease
- Systemic Lupus Erythematosus Research
- Cancer Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Autoimmune and Inflammatory Disorders Research
- Blood disorders and treatments
- Colorectal Cancer Treatments and Studies
- Genomics, phytochemicals, and oxidative stress
- HER2/EGFR in Cancer Research
- Neutropenia and Cancer Infections
- Potassium and Related Disorders
- Prostate Cancer Treatment and Research
- Gastric Cancer Management and Outcomes
- Inflammatory Biomarkers in Disease Prognosis
- Prostate Cancer Diagnosis and Treatment
Kindai University
2002-2025
Chiba University
2019-2024
Nara Medical University Hospital
2021-2024
International University of Health and Welfare
2022-2024
Teikyo University Chiba Medical Center
2019
Tokyo Dental College
2017
Meikai University
2004-2006
Tohoku Medical and Pharmaceutical University
1996
Abstract Given possible involvement of the central and peripheral angiotensin system in pain processing, we conducted clinical preclinical studies to test whether pharmacological inhibition would prevent diabetic neuropathy (DPN) accompanying type 2 diabetes mellitus (T2DM). In study, nociceptive sensitivity was determined leptin-deficient ob / mice, a T2DM model. A retrospective cohort study conducted, using medical records patients receiving antihypertensives at three hospitals for nearly...
<title>Abstract</title> Purpose Anamorelin, a ghrelin-like agonist, was the first drug approved for treatment of cancer-associated cachexia in Japan; however, only few studies have investigated what factors affect discontinuation anamorelin, and observation periods those were short. This study influencing anamorelin after 4, 12, 24, 48 weeks, to include longer than previously assessed. Methods retrospective observational patients who received cancer-related between October 2021 December 2023...
This study aimed to investigate the relationship between renal dysfunction and electrolyte abnormalities, which are adverse events of foscarnet used for cytomegalovirus infection. Of Ninety hematopoietic stem cell transplantation patients, 32 who met selection criteria were enrolled in this retrospective study. The patients divided into two groups according whether they developed dysfunction. incidences hypocalcemia, hypokalemia, hypomagnesemia with an increase grade 2 or higher group 45.5%,...
Antipruritic effects of 70% ethanol extract (CM-ext) Cnidii Monnieri Fructus (dried fruits Cnidium monnieri Cusson, Umberifferae) were investigated. In mice, an oral administration CM-ext (200 and 500 mg/kg) inhibited compound 48/80-induced scratching behavior without influence on spontaneous locomotion. Isopimpinellin (3) osthol (1), coumarin derivatives isolated from CM-ext, showed inhibitory effect behavior.
We aimed to investigate the relationship between voriconazole (VRCZ) trough concentrations and hepatotoxicity evaluate whether recommended concentration is adequate in our clinical setting.A retrospective study was performed serum VRCZ development of at Kindai University Nara Hospital. Patients treated with from March 2010 January 2018 were identified medical records. A total 42 patients (mean age 61.9 ± 16.9 years; 33 males 9 females) enrolled this study.Hepatotoxicity developed 28.6%...
Aims This retrospective cohort study aimed to evaluate the effect of interaction between methotrexate and glucocorticoids on risk developing bacterial infections in patients with rheumatoid arthritis (RA) using biological disease‐modifying antirheumatic drugs (bDMARDs). Methods We used 2005–2018 JMDC claims database, a nationwide database Japan. From 7 175 048 patients, were obtained by applying following exclusion criteria: no use bDMARDs; without information date prescription; RA as...
We investigated predictors of olaparib discontinuation owing to adverse effects. Patients with ovarian, peritoneal, or fallopian tube cancers treated at Osaka Medical and Pharmaceutical University Hospital between April 2018 September 2022 were included in this study. The exclusion criteria as follows: treatment due disease progression, use anaemia medications, cytochrome P450 (CYP3A4) inhibitors. follow-up period was 90 d. Of the 46 eligible patients, 21 patients discontinued olaparib,...
Abstract Background Recent studies have focused on evaluating the biomarker value of textural features in radiological images. Our study investigated whether or not a texture analysis computed tomographic colonography (CTC) images could be novel for colorectal cancer (CRC). Methods This retrospective 263 patients with CRC who underwent contrast‐enhanced CTC (CE‐CTC) before curative surgery between January 2014 and December 2017. Multiple analyses (fractal, histogram, gray‐level co‐occurrence...
Background/Aim: Although the impact of body composition on cancer treatment outcomes patients with has been increasingly reported, it is still unclear whether radiodensity subcutaneous adipose tissue (SAT) computed tomography (CT) images a prognostic gastric cancer. We measured muscle and SAT profiles CT performed an integrated analysis clinicopathologic factors. Patients Methods: retrospectively analyzed 230 who underwent gastrectomy between June 2016 December 2020. (SAT-R), skeletal index...
A β-l, 4-mannan hydrolyzing enzyme was isolated from an extract preparation of Koji culture a strain Asp. niger on wheat bran. After desalting through column Sephadex G-50, the purified by chromatography columns DEAE-Toyopearl 650 S and calcium hydroxylapatite. The optimum pH guar gum about 5, but even at 7. 0, showed activity 70 % that opt. pH. relatively stable to heat active 60°C. hydrolyzed locust bean gum, glucomannan, maximum degrees hydrolysis were 30, 25, 15 %, respectively. In...
We aimed to clarify the drug interaction between tacrolimus and voriconazole investigate relationship blood concentrations of in hematopoietic stem cell transplantation (HSCT) patients.A retrospective study was conducted concentration that at Kindai University Nara Hospital. Patients who received HSCT were prescribed for prevention or treatment aspergillosis from April 2010 July 2018 identified medical records. A total 13 patients (administration route tacrolimus: intravenously 6 patients,...
The aim of this study was to investigate the effect remifentanil infusion on oral tissue blood flow including submandibular gland (SBF) and internal carotid artery (ICBF) in rabbits during sevoflurane anesthesia. Twelve male Japan White were anesthetized with remifentanil. Remifentanil infused at 0.2 0.4 µg/kg/min. Measurements included circulatory variables, common external (CCBF, ECBF), ICBF, tongue mucosal (TMBF), masseter muscle (MBF), mandibular bone marrow (BBF), (TBF) SBF. Vascular...