A5101828114- Synthesis and biological activity
- Cytokine Signaling Pathways and Interactions
- Image and Object Detection Techniques
- Synthesis of Organic Compounds
- Retinal Imaging and Analysis
- Immune cells in cancer
- Flavonoids in Medical Research
- Phytochemicals and Antioxidant Activities
- Neuroinflammation and Neurodegeneration Mechanisms
- Plant biochemistry and biosynthesis
- Physiological and biochemical adaptations
- Carcinogens and Genotoxicity Assessment
- Health, psychology, and well-being
- NF-κB Signaling Pathways
- Robotics and Sensor-Based Localization
- Tryptophan and brain disorders
- Bioactive Compounds and Antitumor Agents
- Fungal and yeast genetics research
- Remote Sensing and LiDAR Applications
- Mycotoxins in Agriculture and Food
- Optical measurement and interference techniques
- Aquaculture disease management and microbiota
- Tea Polyphenols and Effects
- Quantum chaos and dynamical systems
- Stress Responses and Cortisol
Shandong Provincial Hospital
2016-2024
Center for Life Sciences
2024
Intel (United Kingdom)
2024
Bengbu Medical College
2024
Shandong First Medical University
2020-2024
Shandong Freshwater Fisheries Research Institute
2024
Beijing National Laboratory for Molecular Sciences
2024
Peking University
2024
Shandong University
2016-2023
Paclitaxel is a well known anticancer compound. Its biosynthesis involves the formation of highly functionalized diterpenoid core skeleton (baccatin III) and subsequent assembly phenylisoserinoyl side chain. Despite intensive investigation for half century, complete biosynthetic pathway baccatin III remains unknown. In this work, we identified bifunctional cytochrome P450 enzyme [taxane oxetanase 1 (TOT1)] in
In the era of global climate change, increasingly severe Fusarium head blight (FHB) and deoxynivalenol (DON) contamination have caused economic losses brought food feed safety concerns. Recently, an FHB resistance gene Fhb7 coding a glutathione-S transferase (GST) to degrade DON by opening critical toxic epoxide moiety was identified opened new window for wheat breeding detoxification. However, poor stability elusiveness catalytic mechanism hinder its practical application. Herein, we report...
Oxidative stress induces bone loss and osteoporosis, epigallocatechin‐3‐gallate (EGCG) may be used to combat these diseases due its antioxidative property. Herein, oxidative in human marrow‐derived mesenchymal stem cells (BM‐MSCs) was induced by H 2 O , resulting an adverse effect on their osteogenic differentiation. However, this ‐induced nullified when the were treated with EGCG. In addition, treatment of BM‐MSCs EGCG alone also resulted enhancement differentiation BM‐MSCs. After...
Abstract Objectives Curcumin presents some therapeutic effects including anti-cancer and anti-inflammation. Herein, we centred on the functional role of curcumin in cerebral ischaemia injury its potential molecular mechanisms. Methods Microarray analysis was used for excavating crucial genes ischaemia. PC12 cells were subjected to oxygen–glucose deprivation reoxygenation (OGD/R) imitate ischaemia/reperfusion (I/R) vitro. Cell viability apoptosis abilities evaluated by Counting Kit-8 flow...
Recent research has explored the linkage between major depressive disorder (MDD) and inflammation, especially via altered peripheral blood immune markers. However, relationship several novel leukocyte-derived ratios (LDR) psychological stress in MDD remains uncertain. This study aimed to explore LDR, clinical characteristics, recent life events, childhood maltreatment patients.
We investigate the dynamics of quantum scrambling, characterized by out-of-time ordered correlators (OTOCs), in a non-Hermitian kicked rotor subjected to quasi-periodical modulation kicking potential. Quasi-periodic with incommensurate frequencies creates high-dimensional synthetic space, where two different phases scrambling emerge: freezing phase rapid increase OTOCs towards saturation, and chaotic featured linear growth time. find dynamical transition from phase, which is assisted...
This experiment aimed to investigate the effects of emodin on physiological responses and antioxidant gene expression Wuchang bream infected with Aeromonas hydrophila . The experimental diets were prepared supplementing 0, 30, 100 150 mg kg−1 basal (control) diet respectively, fed fish initial weight 50.4 ± 2.35 g. All fish divided into five groups: uninfected control (negative control, NC), supplemented 0 (positive group, PC), 100, kg-1 emodin. reared for 14 days, sampled at different time...
Aiming at the problems of uneven resolution, sparse irregularity, low overlap rate and a large number redundant ground points in airborne LiDAR point cloud data, this paper proposes an intensity-constrained registration algorithm with initial estimation based on segmentation combining motion information. First, rotation transformation relationship adjacent frames can be calculated by normal vector clouds segmented improved RANSAC (Random Sample Consensus) algorithm. Combining parameters...
Optical coherence tomography (OCT) is typically used to identify and diagnose eye diseases due its high resolution non-invasive nature. Synthesizing OCT images by conditional generative adversarial networks (CGAN) can expand the incomplete dataset for model training. This paper aims evaluate whether CGAN network synthesize high-quality that be medical diagnosis, Specially; if trained on real data create of normal retina (NORMAL), vitreous warts (DRUSEN), choroidal neovascularization (CNV),...
junction 402 Cricket ball 204 Cricopharyngeus 71 Crochet needle 493 Cutaneous lesions 360 Cyst 344 -wall excision 465 Cysticercus cyst 118 Dengue 490 -hemorrhagic fever Dense-array EEG 474 Desmoplastic infantile ganglioglioma 422 Developmental abnormality Diabetic ketoacidosis 496 Dialysis 65 Diastematomyelia 418 Diffuse pontine glioma 208 Direct cortical stimulation 313 Disseminated hemangioma Distal catheter migration 49 Distraction osteogenesis 216 Distractor breakage Dural arteriovenous...