Philippe Garot

ORCID: 0000-0002-5069-4149
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About
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Research Areas
  • Cardiac Valve Diseases and Treatments
  • Cardiac Imaging and Diagnostics
  • Infective Endocarditis Diagnosis and Management
  • Aortic Disease and Treatment Approaches
  • Cardiovascular Function and Risk Factors
  • Advanced MRI Techniques and Applications
  • Coronary Interventions and Diagnostics
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiomyopathy and Myosin Studies
  • Atrial Fibrillation Management and Outcomes
  • Peripheral Artery Disease Management
  • Cardiovascular Disease and Adiposity
  • Infrared Thermography in Medicine
  • Acute Myocardial Infarction Research
  • Ultrasound and Hyperthermia Applications
  • Cardiac Arrhythmias and Treatments
  • Machine Learning in Healthcare
  • Cardiac Arrest and Resuscitation
  • Advanced Proteomics Techniques and Applications
  • Health, Environment, Cognitive Aging
  • Healthcare cost, quality, practices

Hôpital Privé Jacques Cartier
2020-2025

Institut Cardiovasculaire Paris Sud
2008-2025

Générale de Santé
2024

Texas Cardiac Arrhythmia
2021

St David's Medical Center
2021

Massachusetts General Hospital
2021

University of Ulsan
2021

Asan Medical Center
2021

Ulsan College
2021

Background: Few randomized trials have compared bioprostheses for transcatheter aortic valve replacement, and no with supra-annular design. The SCOPE 2 trial (Safety Efficacy Comparison of Two TAVI Systems in a Prospective Randomized Evaluation 2) was designed to compare the clinical outcomes ACURATE neo CoreValve Evolut replacement. Methods: performed at 23 centers 6 countries between April 2017 2019. Patients ≥75 years old an indication transfemoral replacement as agreed by heart team were...

10.1161/circulationaha.120.051547 article EN Circulation 2020-10-15

The best management of stable coronary artery disease (CAD) in patients undergoing transcatheter aortic valve implantation (TAVI) is still unclear due to the marked inconsistency available evidence.The REVASC-TAVI registry (Management Myocardial Revascularization Patients Undergoing Transcatheter Aortic Valve Implantation With Coronary Artery Disease) collected data from 30 centers worldwide on TAVI who had significant, CAD at preprocedural work-up. For purposes this analysis, with either...

10.1161/circinterventions.122.012417 article EN Circulation Cardiovascular Interventions 2022-12-01

Coronary obstruction (CO) is a severe complication of transcatheter aortic valve replacement (TAVR). An 80-year-old woman presenting with stenosis was referred for TAVR. A preprocedural computed tomography revealed risk factors CO: narrow root and borderline-low coronary height. During TAVR, both coronaries were protected. After heart (THV) implantation, contrast staining the left sinus leaflet interaction main (LM) ostium noted, prompting LM stenting to prevent obstruction. Because...

10.1016/j.jaccas.2025.103286 article EN cc-by-nc-nd JACC Case Reports 2025-02-01

Abstract Aims This study aimed to determine in patients undergoing stress cardiovascular magnetic resonance (CMR) whether fully automated artificial intelligence (AI)-based left ventricular ejection fraction (LVEFAI) can provide incremental prognostic value predict death above traditional prognosticators. Methods and results Between 2016 2018, we conducted a longitudinal that included all consecutive referred for vasodilator CMR. LVEFAI was assessed using AI algorithm combines multiple deep...

10.1093/ehjci/jeae168 article EN European Heart Journal - Cardiovascular Imaging 2024-07-08

Although the benefit of coronary revascularization in patients with stable disease is debated, data assessing potential interest stress cardiovascular magnetic resonance (CMR) to guide are limited. We aimed assess long-term prognostic value CMR-related consecutive from a large registry.Between 2008 and 2018, retrospective cohort study median follow-up 6.0 years (interquartile range, 5.0-8.0) included all referred for CMR. was defined by any performed within 90 days after The primary outcome...

10.1161/circimaging.121.012789 article EN Circulation Cardiovascular Imaging 2021-10-01

Background/Objectives: To date, data regarding the characteristics and management of obstructive, stable coronary artery disease (CAD) encountered in patients undergoing transcatheter aortic valve implantation (TAVI) are sparse. The aim study was to analyze granular details, treatment, outcomes TAVI with CAD from real-world practice. Methods: REVASC-TAVI (Management myocardial REVASCularization Transcatheter Aortic Valve Implantation disease) is an investigator-initiated, multicenter...

10.3390/jcm13123497 article EN Journal of Clinical Medicine 2024-06-14

Background For high bleeding-risk patients (HBR) undergoing percutaneous coronary intervention (PCI), the LEADERS FREE (LF) and II (LF II) trials established safety efficacy of a stainless steel polymer-free biolimus-coated stent (SS-BCS) with 30 days dual antiplatelet treatment (DAPT). The III III) trial investigated clinical outcomes after PCI next-generation cobalt-chromium thin-strut (CoCr-BCS) in HBR patients. Aims To report final 3-year results LF compare them to II. Methods was...

10.1136/openhrt-2024-002679 article EN cc-by-nc-nd Open Heart 2024-06-01

Background: Recurrence of cardiovascular events remains a substantial cause mortality and morbidity among patients with previous coronary revascularization. The aim was to assess the prognostic value stress magnetic resonance (CMR) parameters in history percutaneous intervention. Methods: Between 2011 2014, consecutive intervention referred for perfusion CMR were followed occurrence major adverse (MACEs), defined by death or nonfatal myocardial infarction. Patients prior artery bypass graft...

10.1161/circimaging.120.012374 article EN Circulation Cardiovascular Imaging 2021-06-01

Abstract Background The polymer‐free biolimus coated stent (BioFreedom) was shown to be superior bare metal stents in the LEADERS FREE randomized trial high bleeding risk (HBR) patients treated with 1‐month dual antiplatelet therapy (DAPT). However, there is limited outcome data this device an all‐comers' population. Methods We conducted a prospective single‐arm study of undergoing percutaneous coronary intervention 25 centers France wide inclusion criteria including multivessel disease,...

10.1002/ccd.30481 article EN Catheterization and Cardiovascular Interventions 2022-11-15

Severe paravalvular leak (PVL) may be complicated by heart failure and haemolysis. PVL management is challenging, especially when the gap large. We describe a case of due to tilting sutureless biological prosthesis successfully treated transcatheter aortic valve replacement (TAV-in-SAV).

10.1016/j.jaccas.2024.102270 article EN cc-by-nc-nd JACC Case Reports 2024-02-23

In this state-of-the-art review, we present the findings and a critical analysis of Leaders Free trial program, evaluating outcomes new stent-generation based on polymer-free technology, in case BioFreedom™ (Biosensors Europe, Switzerland), patients at high bleeding risk (HBR). Polymer-free drug-coated stents were designed to obtain device with antirestenotic benefits drug-eluting but without polymer coating as potential trigger for delayed arterial wall healing subsequent late ischemic...

10.2217/fca-2020-0069 article EN Future Cardiology 2020-09-07

ABSTRACT Background Evidence regarding sex-related differences in response to transcatheter aortic valve implantation according the type is lacking. This study sought evaluate impact of sex on treatment effect Evolut-PRO/PRO+ (PRO) or Sapien 3 Ultra (ULTRA) devices clinical outcomes. Methods Comparative Analysis Evolut PRO vs Valves for Transfemoral Transcatheter Aortic Valve Implantation (OPERA-TAVI) a multicenter multinational registry including patients undergoing latest-iteration ULTRA...

10.1101/2023.09.05.23295098 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2023-09-07

Objectives and background Magnetic resonance imaging (MRI) has been used to delineate the extent of acute myocardial infarction in coronary artery disease, but its role after ethanol induced septal not largely assessed. We report evaluation by alcohol ablation (ASA) patients with symptomatic hypertrophic obstructive cardiomyopathy using contrast enhanced MRI.

10.1186/1532-429x-10-s1-a83 article EN cc-by Journal of Cardiovascular Magnetic Resonance 2008-10-01
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