- Nanoplatforms for cancer theranostics
- Wound Healing and Treatments
- Minerals Flotation and Separation Techniques
- Metal Extraction and Bioleaching
- Advanced Photocatalysis Techniques
- Advanced biosensing and bioanalysis techniques
- 2D Materials and Applications
- MXene and MAX Phase Materials
- RNA Interference and Gene Delivery
- Graphene and Nanomaterials Applications
- Electrocatalysts for Energy Conversion
- Antimicrobial Peptides and Activities
- Bone Tissue Engineering Materials
- Antimicrobial agents and applications
- Circular RNAs in diseases
- Extraction and Separation Processes
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Peptidase Inhibition and Analysis
- Pediatric health and respiratory diseases
- Chalcogenide Semiconductor Thin Films
- Electrochemical Analysis and Applications
- Silk-based biomaterials and applications
- Advanced oxidation water treatment
- Dendrimers and Hyperbranched Polymers
Xi'an Jiaotong University
2016-2024
Central South University
2016-2021
Second Affiliated Hospital of Xi'an Jiaotong University
2018-2019
82th Hospital of Pla
2015
Peking University
2009
Phase engineering of nanomaterials provides a promising way to explore the phase-dependent physicochemical properties and various applications nanomaterials. A general bottom-up synthesis method under mild conditions has always been challenging globally for preparation semimetallic phase-transition-metal dichalcogenide (1T'-TMD) monolayers, which are pursued owing their unique electrochemical property, unavailable in semiconducting 2H phases. Here, we report scalable colloidal nanosized...
The bone defects caused by trauma are inevitably accompanied soft tissue damage. development of multifunctional bioactive biomaterials with integrated and regeneration is necessary needed urgently in orthopedics. In this work, we found that the photoactivated MXene (Ti3C2Tx) nanosheet showed positive effects on promoting both regeneration. We further investigated detailed effect potential mechanism Photoactivated shows a good thermal robust antibacterial activity to inhibit expression...
Abstract Polyether ether ketone (PEEK) has become one of the most promising polymer implants in bone orthopedics, due to biocompatibility, good processability, and radiation resistance. However, poor mechanics‐adaptability/osteointegration/osteogenesis/antiinfection limits long‐term vivo applications PEEK implants. Herein, a multifunctional implant (PEEK‐PDA‐BGNs) is constructed through situ surface deposition polydopamine‐bioactive glass nanoparticles (PDA‐BGNs). PEEK‐PDA‐BGNs exhibit...
Postsurgical tumor recurrence, infection, and tissue defect are still the challenges in clinical medicine. The development of multifunctional biomaterial scaffolds with a microenvironment-responsive tumor-infection therapy-tissue repair is highly desirable. Herein, we report bioactive, injectable, adhesive, self-healing, antibacterial, anti-inflammatory metal-polyphenol polypeptide nanocomposite scaffold (PEAPF) temporal-spatial-controlled inflammation-triggered therapeutic properties for...
Chronic obstructive pulmonary disease (COPD) is a progressive, irreversible chronic inflammatory disorder typified by increased recruitment of monocytes, lymphocytes and neutrophils. Because this, as well the convenience peripheral blood nuclear cells (PBMCs) assessments, miRNA profiling PBMCs has drawn increasing attention in recent years for various disease. Therefore, we analyzed mRNA profiles to understand their regulatory network between COPD subjects versus smokers without airflow...
Abstract The inhibition of inflammation and the promotion early angiogenesis are paid much attention in skin tissue engineering. Citric acid‐based biomaterials widely used engineering due to their bioactive structure biocompatibility, but there few studies on investigating role mechanism wound repair regeneration. Herein, potential anti‐inflammation poly(octanediol‐citrate‐polyglycol) (POCG) copolymer is reported regulating repair. It found that POCG can modulate macrophages phenotype...
1T'-phase MoS2 possesses excellent electrocatalytic performance, but due to the instability of thermodynamic metastable phase, its actual effect is seriously limited. Here, we report a wet-chemical synthesis strategy for constructing rGO/1T'-MoS2/CeO2 heterostructures improve phase stability 1T' monolayers. Importantly, heterostructure exhibits hydrogen evolution reaction (HER) which much better than 1T'-MoS2 The synergistic effects between CeO2 nanoparticles (NPs) and monolayers were...
Janus monolayers of transition metal dichalcogenides (TMDs) offer versatile applications due to their tunable polymorphisms. While previous studies focused on conventional 2H-phase monolayers, the scalable synthesis an unconventional 1T' phase remains challenging. We present a novel solution strategy for fabricating 1T'-MoOSe and MoSSe by growing sandwiched Se-Mo-O/S shells onto Au nanocores. The Au@1T'-MoSSe catalyst exhibits superior electrocatalytic hydrogen evolution reaction (HER)...
Colon cancer is one of the most common gastrointestinal tumors in world. Currently, commonly used methods such as radiotherapy, chemotherapy and drug treatments are often ineffective have significant side effects. Here we developed a safe efficient biomaterials based anti-tumor nanoplatform (M@NPs/miR365), which was formed with poly (citrate-peptide) (PCP), miRNA365 mimic MC38 cell membrane (M). PCP could efficiently deliver miR365 into cells, promote apoptosis tumor cells regulate...
Unconventional 1T′ phase transition metal dichalcogenides (TMDs) show great potential for hydrogen evolution reaction (HER). However, they are susceptible to transitioning into the stable 2H phase, which reduces their catalytic activity and stability. Herein, we present a scalable approach designing thermally 1T′‐TMDs hollow structures (HSs) by etching Cu1.94S templates from pre‐synthesized Cu1.94S@TMDs heterostructures, including 1T′‐MoS2, MoSe2, WS2, WSe2 HSs. Furthermore, taking 1T′‐MoS2...
This study aimed to investigate the expressional profile of interleukin-6 (IL-6) in articular cartilage bone osteoarthritis (OA) patients and its correlation with OA. A total 30 samples from knee OA patients, which were collected by arthroscopy or surgery, comprised group, normal tissue control group. Both mRNA (messenger ribonucleic acid) protein levels IL-6 matrix metalloproteinase-9 (MMP-9) measured compared, a analysis was performed between two. The integral optical density (IOD) values...