A5013649552- Orthopedic Surgery and Rehabilitation
- PARP inhibition in cancer therapy
- dental development and anomalies
- Bone fractures and treatments
- Digestive system and related health
- Rheumatoid Arthritis Research and Therapies
- Prosthetics and Rehabilitation Robotics
- Acupuncture Treatment Research Studies
- Circular RNAs in diseases
- Facial Rejuvenation and Surgery Techniques
- Osteoarthritis Treatment and Mechanisms
- Inflammatory mediators and NSAID effects
- Bioactive Compounds and Antitumor Agents
- Circadian rhythm and melatonin
- MicroRNA in disease regulation
- Cell death mechanisms and regulation
- Bone and Dental Protein Studies
- Cancer therapeutics and mechanisms
- Toxin Mechanisms and Immunotoxins
- Inflammasome and immune disorders
- Foot and Ankle Surgery
- Synthesis and bioactivity of alkaloids
- Healthcare and Venom Research
- Muscle activation and electromyography studies
- Medical Research and Treatments
Southwest Medical University
2021-2025
Huazhong University of Science and Technology
2024-2025
Tongji Hospital
2024-2025
Nanjing University
2025
Hunan University of Traditional Chinese Medicine
2022
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2022
Stomatology Hospital
2022
Daping Hospital
2021
Army Medical University
2021
Weatherford College
2021
In addition to their established action of synthetic lethality in tumor cells, poly(ADP-ribose) polymerase inhibitors (PARPis) also orchestrate immune microenvironment (TIME) that contributes suppressing growth. However, it remains not fully understood whether and how PARPis trigger tumor-targeting responses.
To investigate the correlation between anterior talofibular ligament (ATFL) injury and pathological changes of tibiotalar fat pad (ATFP) based on MRI. The clinical imaging data 217 patients with ankle sprain who met selection criteria January 2019 March 2024 were retrospectively analyzed. There 113 males 104 females an average age 38.2 years ranging from 18 to 60 years. Patients divided into mild group ( n=106), moderate n=63), severe n=48) according degree ATFL injury. was no significant...
<title>Abstract</title> Post-translational modifications (PTMs) in congenital malformations like cleft palate are gradually being elucidated. It has been shown that O-GlcNAcylation as a dynamic PTM of proteins regulates various critical biological processes such transcription, translation and cell fate determination. In this study, substantial decline was detected O-linked β-D-N-acetylglucosamine (O-GlcNAc) levels within the palatine plates all-trans retinoic acid (atRA)-induced mice. The...
Preeclampsia (PE) is a pregnancy-specific multisystem disease as well an important cause of maternal and perinatal death. This study aimed to analyze the placental transcriptional data clinical information PE patients available in published database predict target genes for prevention PE.The corresponding RNA were downloaded from GEO database. Cluster analysis was performed examine correlation between different genotyping manifestations. Then, bioinformatic approaches including GO, KEGG,...
Objective: Tooth morphogenesis and the formation of hard tissues have been reported to be closely related circadian rhythms. This study investigates spatiotemporal expression relationship p75NTR with core clock genes, mineralization-related or odontogenesis-related aims derive potential role in regulating rhythm incrementality growth line during tooth development. Materials methods: The dynamic morphology rat dental germ was observed at seven stages (E14.5 d, E16.5 E18.5 P.N. 4 7 10 15 d)....
BACKGROUNDBimaxillary protrusion is a clinically common dentofacial deformity, particularly among Chinese patients.This kind of malformation can severely affect facial esthetics and, even in mild cases, difficult to correct without surgery.Unfortunately, many patients abandon treatment because fear surgery.Here, we describe case severe skeletal bimaxillary treated with nonsurgical orthodontic treatments, highlighting an alternative option. CASE SUMMARYA 31-year-old woman wished address...
Knee osteoarthritis (KOA) is a common degenerative joint disease. In this study, we aimed to identify new biomarkers of KOA improve the accuracy diagnosis and treatment.GSE98918 GSE51588 were downloaded from Gene Expression Omnibus database as training sets, with total 74 samples. differences analyzed by Ontology, Kyoto Encyclopedia Genes Genomes pathway, Disease Ontology enrichment analyses for differentially expressed genes (DEGs), GSEA analysis was carried out gene set. Through least...
Acupuncture combined with traditional Chinese medicine (TCM) bonesetting is an effective and more acceptable treatment method for distal radius fractures; this study aims to evaluate the clinical efficacy other relevant factors of it compared western therapy such as operation.Databases CNKI, Wanfang, VIP, SinoMed, PubMed were searched current study. The retrieval time was from establishment November 14, 2021. Literature quality evaluated according bias risk assessment criteria Cochrane...
Abstract Mage-D1 (MAGE family member D1) is involved in a variety of cell biological effects. Recent studies have shown that closely related to tooth development, but its specific regulatory mechanism unclear. The purpose this study was investigate the expression pattern rat dental germ development and differential mineralization ability ectomesenchymal stem cells (EMSCs), explore potential mechanism. Results showed during temporally spatially specific. promotes proliferation EMSCs inhibits...
Abstract Mage-D1 (MAGE family member D1) is involved in a variety of cell biological effects. Recent studies have shown that closely related to tooth development, but its specific regulatory mechanism unclear. The purpose this study was investigate the expression pattern rat germ development and differential mineralization ability ectomesenchymal stem cells (EMSCs), explore potential mechanism. Results showed during temporally spatially specific. promotes proliferation EMSCs inhibits their...