- interferon and immune responses
- Biochemical and Molecular Research
- DNA Repair Mechanisms
- Cancer-related Molecular Pathways
- Nuclear Receptors and Signaling
- Cancer Research and Treatments
- Ubiquitin and proteasome pathways
- Hormonal Regulation and Hypertension
- Renin-Angiotensin System Studies
- Mercury impact and mitigation studies
- Receptor Mechanisms and Signaling
- Heavy Metal Exposure and Toxicity
- Melamine detection and toxicity
Nanjing Medical University
2024
Nankai University
2024
Abstract Candesartan is a common angiotensin‐II receptor‐1 blocker used for patients with cardiovascular and renal diseases. Angiotensin‐converting enzyme 2 (ACE2) negative regulator of blood pressure (BP), also major receptor coronaviruses. To determine whether how candesartan upregulates ACE2, we examined BP ACE2 in multi‐organs from male female C57BL/6J mice treated (1 mg/kg, i.p.) 7 days. Relative to the vehicle, lowered more males than females; protein abundances were increased kidneys,...
Mercury nanoparticles are abundant in natural environments. Yet, understanding their contribution to global biogeochemical cycling of mercury remains elusive. Here, we show that microbial transformation nanoparticulate divalent can be an important source elemental and methylmercury.