A5087949062- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Vascular Procedures and Complications
- Infectious Aortic and Vascular Conditions
- Cardiac Imaging and Diagnostics
- Kawasaki Disease and Coronary Complications
- Cardiac Arrhythmias and Treatments
- Cardiac Valve Diseases and Treatments
- Renal and Vascular Pathologies
- Sarcoidosis and Beryllium Toxicity Research
- Abdominal vascular conditions and treatments
- Medical Imaging and Pathology Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Coronary Interventions and Diagnostics
Vienna General Hospital
2020-2024
Medical University of Vienna
2020-2024
Abstract In this observational case-control study, circulating levels of complement factors C3a and C5a leukotriene B4 (LTB4) were analysed in abdominal aortic aneurysm (AAA) patients regarding their association with diagnosis prognosis. Serum was significantly raised AAA compared to healthy controls—median 84.5 ng/ml (IQR = 37.5 ng/ml) vs. 67.7 26.2 ng/ml), p 0.007—but not elevated athero-occlusive disease. correlated the increase maximum diameter over following 6 months ( r 0.319, 0.021)....
The maximal aortic diameter is currently the only clinically applied predictor of abdominal aneurysm (AAA) progression. It known that risk rupture associated with size; hence, accurate monitoring AAA expansion crucial. Aneurysmal vessel wall calcification and its implication on are insufficiently explored. We evaluated vascular using longitudinal computed tomography angiographies (CTA) patients an association growth.We conducted a retrospective study 102 total 389 CTAs at 6-month intervals,...
Neutrophil extracellular traps (NETs) are DNA-protein structures released by neutrophils in response to various stimuli, including oxidized, low-density lipoprotein (oxLDL). Accumulating evidence suggests a role for NETs the pathogenesis of abdominal aortic aneurysm (AAA). In this study, we investigated potential association particles and AAA comparison non-AAA control groups. The concentrations neutrophil myeloperoxidase (MPO), NET parameters citrullinated histone H3 (citH3) circulating...
Background Abdominal aortic aneurysm (AAA) development is driven by inflammation, in particular myeloid cells, which represent attractive biomarker candidates. Yet to date, the maximum diameter only clinically applied predictor of AAA progression and indicator for surgical repair. We postulated that inflammation reflected a systemic change monocyte populations, we investigated regarding marker potential diagnosis prognosis. Methods conducted single-center retrospective cohort study...
Background201Tl myocardial scintigraphy (201Tl SPECT) is of strong prognostic value in various populations with suspected or known coronary artery disease. However, its patients bypass grafting (CABG) not fully assessed.Methods We examined 115 consecutive to determine the relation between clinical data/stress 201Tl SPECT performed 5±3 years after CABG, and subsequent cardiac events.Results Thirteen (11%) had stress-induced angina, 22 (19%) electrical positivity, 97 (84%) abnormal...
Abdominal aortic aneurysm (AAA) and peripheral artery disease (PAD) share pathophysiological mechanisms including the activation of fibrinolytic innate immune system, which explains analysis D-dimer myeloperoxidase (MPO) in both conditions. This study evaluates diagnostic marker potential variables separately as a combined MPO/D-dimer score for identifying patients with AAA versus healthy individuals or PAD. Plasma levels MPO were increased PAD compared to controls (median MPO: 13.63 ng/mL...
Abdominal aortic aneurysm (AAA) is a multifactorial vascular disease associated with high morbidity and mortality. Currently, surgical intervention the only treatment option, there no drug therapy available for AAA. Hence, surveillance of AAA until indication surgery may impact patient quality life (QoL). There paucity high-quality observational data on health status QoL, particularly among patients participating in randomized controlled trials. The objective this study was to compare QoL...