To explore the mechanism of drug release and depot formation in situ forming implants (ISFIs), osthole-loaded ISFIs were prepared by dissolving polylactide, poly(lactide-co-glycolide), polycaprolactone, or poly(trimethylene carbonate) different organic solvents, including N-methyl-2-pyrrolidone (NMP), dimethyl sulfoxide (DMSO), triacetin (TA). Drug release, polymer degradation, solvent removal rate microstructure examined. The burst effect could be reduced using solvents exhibit slow phase...

There is no well-established procedure for the management of small penis syndrome (SPS), especially when psychological interventions fail. This study aimed at systematically evaluating physical and benefits penile augmentation (PA) using injectable hyaluronic acid (HA) gel. Thirty-eight patients receiving PA with HA gel from January 2017 to March 2020 were included followed up 1 year. Penile size, erectile function, burden measured by Index Male Genital Image (IMGI), International Erectile...

The super-precise theory for machining single crystal SiC substrates with abrasives needs to be improved its chemical stability, extremely hard and brittle. A Berkovich indenter was used carry out a systematic static stiffness indentation experiments on 6H-SiC substrates, then these were machined by utilizing fixed, free, semi-fixed abrasives, the nanomechanical characteristics material removal mechanisms using in different fixed methods analyzed theoretically. results indicated that...

A method based on the analysis of x-ray photoelectron spectra (XPS) N1s in FeN material, which can be used to directly evaluate volume ratio α''-Fe16N2, is presented. The binding energies three possible iron nitride, including α'-Fe8N, α''-Fe16N2 and ץ΄-Fe4N, are determined experimentally. Based these specific contributions, XPS deconvoluted phases' ratios evaluated. This also thin film samples.The comparison between traditional diffraction results shows that two methods provide same values...

Semiconductor silicon plays a significant role in the microelectronics industry. In this paper, effects of polishing pressure on electrochemical characteristics wafers during chemical mechanical (CMP) were investigated by dc polarization and ac impedance techniques. The results revealed that had strong influence behavior wafers. Mechanical abrasion improved removal passivating layer enhanced wafer oxidation rate. corrosion current density rate increased sublinearly with applied pressure....

Abstract Aiming at the process of magnetorheological (MR) polishing, we analyzed characteristics polishing forces (normal force [Fn] and tangential [Ft]) in a machining by using Kistler 9171A 3-d rotating dynamometer. The influences rotation speeds magnetic poles workpiece, abrasive concentration, concentration carbonyl iron powders, working gaps, deflection distance workpiece on MR with dynamic fields were investigated. results showed that pads static significantly attenuated. For under...

Peptide dendrimers are attractive nonviral gene vectors. But a biological barrier for their application in delivery is the fast degradation catalyzed by proteasomes. Proteasome inhibitors efficient at prohibiting of peptide vectors, thus enhancing transfection efficiency. In this study, N α -Boc-protected leucine vinyl ester proteasome inhibitor Boc-Leu-Leu-Leu-ve was synthesized liquid-phase method and then immobilized onto poly(l-lysine) dendrimers. Suc-Leu-Leu-Val-Tyr-AMC used as...

Semiconductor silicon plays a significant role in microelectronic industries. In this paper, the effects of concentration on electrochemical characteristics wafers during chemical mechanical polishing (CMP) as well under static conditions were investigated by dc polarization and ac impedance techniques. The results revealed that had strong influence behaviors wafers. passivation strengthened with increasing condition. addition into slurry increased potential drop between conditions, maximal...

Surface adsorption of N2 molecules is a critical factor to limit the reduction secondary electron (SE) yield (SEY) in many fields applied physics. On basis Polanyi potential theory, we describe multi-layer physical model arrange distribution adsorbed on Cu (1 1 0) surface. Considering six scattering types, used Monte Carlo method develop three-dimensional numerical that simulated processes between electrons and molecules. Thus, SEY surface covered by an layer could be obtained statistical...

For determination of the Avogadro's number, a self‐referenced lattice comparator established at Photon Factory to deal with d‐spacing mapping measurement over cross section 4 ∼ 5 inches FZ silicon rod. uncertainty 1×10−8 unit cell volume, it is necessary measure parameter resolution 3×10−9 least. In this paper, we report principle our comparator, characterize system, and show some results 3×10−9.

Much of the rare-event simulation literature is concerned with development asymptotically optimal algorithms. Because difficulties associated applying these ideas to complex models, this paper focuses on sub-optimal procedures that can be shown much more efficient than conventional crude Monte Carlo. We provide two such examples, one based repeated acceptance/rejection as a mean computing tail probabilities for hitting time random variables and other filtered conditional

Waveguide grating filter with an antireflective surface is designed by using the equivalent homogeneous thin-film model. The spectral properties are investigated rigorous method based on calculated parameters. It shown that model may provide a reliable approximation in estimating resonance locations of filters even for surface-relief structure. validity design decreases increase refractive index contrast layer fixed filling factor.

Abstract Aiming at the disadvantages of existing conveyor belt flow monitoring, this research builds a optical dynamic flow-meter based on field programmable gate array (FPGA) by using FPGA image processing technology and method measuring material volume to measure material, which uses principle laser triangulation. The takes as core drives two complementary metal oxide semiconductor (CMOS) cameras collect light strips surface same time. Then, filter, binarization, center extraction...

SWOT method is an important tool in the research and development of strategic planning process. Using method, analytical framework model for equipment strategy assessment developed, environment analysis weapons carried out, impact

Wideband reflector and bandpass filter are obtained by using a Ge subwavelength periodic membrane with the thickness kept constant at 3.20 μm. The strong refractive-index modulation of yields increased bandwidth leaky mode resonances, thus excitation resonances TE_1,1, TE_2,1, TE_3,0 may interact to form broad reflection band or transmission passband near λ=10.60 μm.

The active power filter is one of effective means to solve the harmonic pollution caused by nonlinear load. Based on synchronous rotating coordinate, an improved extract and current control strategy combining PI with deadbeat proposed. This can make a selective show direct coordinate transformation digital low-pass filter, so as realize detection current, input commands fundamental outputted from regulators into controller, finally, compensation effectively. shunt APF experimental platform...