A5101540689- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Urinary Tract Infections Management
- Inflammatory mediators and NSAID effects
- Prostate Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Peptidase Inhibition and Analysis
- Cancer, Lipids, and Metabolism
- Cell Adhesion Molecules Research
- Urological Disorders and Treatments
- Estrogen and related hormone effects
- Ureteral procedures and complications
- Autophagy in Disease and Therapy
- Anorectal Disease Treatments and Outcomes
- Adipokines, Inflammation, and Metabolic Diseases
- Atherosclerosis and Cardiovascular Diseases
- Gastric Cancer Management and Outcomes
- Traditional Chinese Medicine Studies
- Cardiovascular Disease and Adiposity
- Hormonal and reproductive studies
- Growth Hormone and Insulin-like Growth Factors
- Cancer-related molecular mechanisms research
- Marine Sponges and Natural Products
- Genomic variations and chromosomal abnormalities
- Advanced biosensing and bioanalysis techniques
Shanghai University of Traditional Chinese Medicine
2025
Guangxi University
2018-2025
Guangxi University of Chinese Medicine
2025
Xi'an Jiaotong University
2023-2024
Third People's Hospital of Yunnan Province
2024
Qingdao Municipal Hospital
2024
Qingdao University
2024
Skin Wellness Center
2024
Shanghai Jiao Tong University
2011-2023
Renji Hospital
2009-2023
Background: Gastrointestinal motility disorder (GMD) is a common condition characterized by dysfunction or degeneration of the myenteric plexus in specific segments gastrointestinal tract. Liupao tea (LPT) post-fermented that rich various secondary metabolites and has demonstrated range pharmacological effects, including lipid-lowering properties, antioxidant activity, modulation gut microbiota. However, underlying mechanisms which LPT improves GMD remain poorly understood. Methods: Blood...
Interstitial cystitis/bladder pain syndrome (IC/BPS) is characterized by overexpression of monocyte chemoattractant protein-1 (MCP-1) in bladder tissues and induction mast cell (MC) degranulation. This study was undertaken to explore the mechanism action MCP-1 development IC/BPS.A rat model IC/BPS developed perfusing bladders nine SPF- grade female Sprague-Dawley rats with protamine sulfate lipopolysaccharide (PS+LPS). histamine levels tissue urine were detected immunohistochemistry ELISA....
Atherosclerosis (AS) is a chronic inflammatory vascular disease closely tied to cellular metabolism. Recent genome-wide association study data have suggested that the significant roles of endothelial cells, smooth muscle and macrophages in regression exacerbation AS. However, impact crosstalk metabolic derangements on progression AS vaguely understood. In this review, we analyze three cell types We also summarize between two them, associated molecules consequences involved. addition,...
Although high-mobility group A2 (HMGA2) protein has been reported to participate in cancer progression and metastasis, its clinical relationship with tumor invasion, lymph node prognosis esophageal squamous cell carcinoma (ESCC) remains unclear. The purpose of this study is analyze the prognostic significance HMGA2 ESCC patients after curative resection.The expression was evaluated by using immunohistochemistry a tissue microarray (TMA) containing lesions adjacent normal epithelial tissues...
Abstract Background Pitt–Hopkins syndrome (PTHS) is a neurodevelopmental disorder that remains underdiagnosed and its clinical presentations mutation profiles in diverse population are yet to be evaluated. This retrospective study aims investigate the genetic characteristics of Chinese patients with PTHS. Methods The clinical, biochemical, genetic, therapeutic, follow-up data 47 pediatric diagnosed PTHS between 2018 2021 were retrospectively analyzed. Results presented specific facial...
Our present study investigated monocyte chemoattractant protein-1 (MCP-1) expression in bladder tissue and urine from interstitial cystitis (IC) patients. Totally 35 patients with IC, 20 urinary tract infection (UTI) 25 healthy subjects were recruited into this study. IC was diagnosed according to the NIDDK Diagnosis Standard. All received 24 h voiding diaries, O’Leary-Sant questionnaires, potassium sensitivity test (PST) cystoscopy. RT-PCR ELISA used determine levels of MCP-1 tissues...
To compare the efficacy and safety of 30 mg extended release (ER) formulation propiverine hydrochloride with 4 ER tolterodine tartrate in patients overactive bladder (OAB) a non-inferiority trial.Eligible patients, aged 18-75 years symptoms OAB, were enrolled this multicentre, randomized, double-blind, parallel-group, active-controlled study. After 2-week screening period, randomized at 1:1 ratio to receive either or daily during 8-week treatment period. Efficacy was assessed using 3-day...
BACKGROUND The development of laparoscopic technology has provided a new choice for surgery gastric cancer (GC), but the advantages and disadvantages total gastrectomy (LTG) laparoscopic-assisted (LATG) in treatment effect safety are still controversial. purpose this study is to compare efficacy two methods GC, provide basis clinical decision-making. AIM To totally LTG (TLTG) LATG context radical GC. Additionally, we investigated feasibility esophagojejunostomy technique. METHODS Literature...
Abstract Objective The aim of this study is to investigate the relationship leukocytes DNA methylation in targeted sites and thrombophilia. Methods Eight thrombophilia patients their kin-related individuals as healthy control. Targeted from peripheral were examined with MassArray. Multivariate correlation analysis was used estimate gene an independent risk factor Receiver operating characteristic curve calculate accuracy biomarkers prediction Results age group higher than control ( P <...
The goal of this study was to assess the efficacy saw palmetto-based nutritional supplement, Prostataplex, for relieving symptoms associated with benign prostatic hyperplasia (BPH) in men mild moderate degrees BPH. A randomized, double-blind, placebo-controlled trial performed Shanghai, China. Eighty patients BPH were randomly assigned either intervention group (39 cases) or control (41 cases). Patients administered Prostataplex orally and placebos given group. duration treatment 12 weeks...
Human plasminogen activator inhibitor-1 (PAI-1) is an important component of the coagulation system and has been recognized as a potential therapeutic target diverse cardiovascular disorders. Previously, it was found that extracts from Chinese medicine Dracaena dragon blood have potent inhibitory activity against PAI-1, but unclear which constituents directly participate in inhibition how do they regulate PAI-1 at molecular level. Here, we describe integrated strategy to identify blood's...