Xiaohong Guo

ORCID: 0000-0003-1770-0639
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Liver physiology and pathology
  • Cancer-related molecular mechanisms research
  • Growth Hormone and Insulin-like Growth Factors
  • Soil Carbon and Nitrogen Dynamics
  • Adipokines, Inflammation, and Metabolic Diseases
  • Microbial Community Ecology and Physiology
  • Technology Adoption and User Behaviour
  • Electrochemical Analysis and Applications
  • Analytical chemistry methods development
  • MicroRNA in disease regulation
  • Heavy metals in environment
  • Cancer Mechanisms and Therapy
  • Cancer-related gene regulation
  • Acute Ischemic Stroke Management
  • Circular RNAs in diseases
  • RNA modifications and cancer
  • Fault Detection and Control Systems
  • Protein Hydrolysis and Bioactive Peptides
  • Lymphatic System and Diseases
  • Cancer-related Molecular Pathways
  • Mechanisms of cancer metastasis
  • Epigenetics and DNA Methylation
  • Berberine and alkaloids research
  • Arsenic contamination and mitigation

Hubei University of Chinese Medicine
2019-2025

Shanxi Medical University
2009-2024

First Hospital of Shanxi Medical University
2009-2024

Shanxi Agricultural University
2004-2024

Jinan University
2024

Zhuhai People's Hospital
2024

Ludong University
2017-2023

First Affiliated Hospital of Zhengzhou University
2023

China Academy of Space Technology
2017-2022

Yantai Institute of Coastal Zone Research
2013-2022

Accumulating evidence has revealed that aberrantly expressed long non-coding transcripts are involved in the development and progression of colorectal cancer (CRC). Small nucleolar RNA host gene 3 (SNHG3) is a newly identified lncRNA, little known about its clinical significance biological functions CRC. In present study, we found expression SNHG3 was significantly upregulated CRC, upregulation predicted poor prognosis for patients with CRC as determined through analysis data obtained from...

10.3892/or.2017.5837 article EN cc-by-nc-nd Oncology Reports 2017-03-01

A novel, compact, and green method was developed for the determination speciation analysis of mercury, based on flow injection photochemical vapor generation (PVG) coupled with miniaturized solution cathode glow discharge-atomic emission spectroscopy (SCGD-AES). The SCGD generated between a miniature hollow titanium tube emerging from glass capillary. Cold mercury (Hg(0)) by PVG subsequently delivered to excitation, finally signals were recorded spectrograph. detection limits (DLs) Hg(II)...

10.1021/acs.analchem.7b02214 article EN Analytical Chemistry 2017-09-01

In this study, miniaturized optical emission spectrometry (OES) based on solution cathode glow discharge (SCGD) was developed for the determination of metal elements in samples.

10.1039/c8ja00369f article EN Journal of Analytical Atomic Spectrometry 2018-12-03

Our previous study found that insulin-like growth factor binding protein-associated protein (IGFBPrP1) drives hepatic stellate cells (HSCs) activation, and IGFBPrP1 transforming β1 (TGFβ1) likely interact with each other to promote HSCs activation. TGFβ1 reportedly promotes autophagy contributes activation; however, the mechanism between in liver fibrogenesis is yet unknown. Moreover, long noncoding RNA (lncRNA) H19 participates regulation plays a crucial function fibrosis. To define...

10.1016/j.biopha.2019.109034 article EN cc-by-nc-nd Biomedicine & Pharmacotherapy 2019-05-29

The pharmacological action of morphine as a pain medication is mediated primarily through the mu-opioid receptor (MOR). With few exceptions, MOR expressed in brain regions where opioid actions take place. basis for this unique spatial expression remains undetermined. Recently, we reported that DNA methylation promoter plays an important role regulating P19 cells. In study, show differential microdissected mouse coincides with and histone modifications. could be induced by demethylating agent...

10.1111/j.1582-4934.2008.00535.x article EN other-oa Journal of Cellular and Molecular Medicine 2008-10-13

10.1007/s10257-016-0315-x article EN Information Systems and e-Business Management 2016-03-19

This paper empirically examines the effects of critical determinants such as universal access, satisfaction, reputation, and familiarity on purchase intentions for wearable devices through a paradigm trust social benefit. Data was collected from an online survey. The formal questionnaire consisted two sections. first section measured respondent perceptions each construct in research model. second interpreted basic personal data respondents. study results indicate that both benefit can...

10.1177/0266666916635724 article EN Information Development 2016-02-26

Abstract Background Dihydroartemisinin (DHA) is an artemisinin derivative known for its antimalarial properties. It has also shown potential as anti‐tumor and anti‐angiogenic agent. However, specific role in inhibiting angiogenesis breast cancer not well understood. Objectives We aimed to investigate the anti‐angiogenesis effect of DHA on explore a therapeutic drug. Our objectives were assess impact neovascularization induced by MDA‐MB‐231 cells, evaluate effects vessel sprout tube‐formation...

10.1111/fcp.12941 article EN Fundamental and Clinical Pharmacology 2023-07-25

The biochar and organic fertilizer amendment have been used as an effective practice to increase soil fertility. Nevertheless, the mechanisms of microbial community response application on saline-alkali not clarified. This study investigated effects at different concentrations wheat rhizosphere under field experiment in Yellow River Delta (China, YRD), using high-throughput sequencing technology. Biochar significantly influenced most parameters (p < 0.05), apart from moisture content (M),...

10.3389/fmicb.2023.1250453 article EN cc-by Frontiers in Microbiology 2023-09-22

Occludin plays an important role in maintaining tight junction barrier function many types of epithelia. We previously reported that activation transient receptor potential vanilloid subtype 1 (TRPV1) rabbit submandibular gland promoted salivary secretion, partly by increase paracellular permeability. have now explored the occludin TRPV1-modulated permeability a rat cell line SMG-C6. Both TRPV1 and were expressed SMG-C6 cells, capsaicin induced redistribution occludin, but not claudin-3,...

10.1242/jcs.111781 article EN Journal of Cell Science 2013-01-24

Capsaicin (CAP) exerts significant anti-tumor effects on a variety of tumors, with low intrinsic toxicity.Cisplatin (DDP) is currently the first-line drug for treatment oral cancer; however, its clinical efficacy impeded by chemoresistance and negligible side effects.Whether combined use CAP DDP has synergistic antitumor effect tongue squamous cell carcinoma (TSCC) cells underlying mechanisms remains unclear.The present study revealed that reduced activity TSCC in dose-and time-dependent...

10.7150/jca.98075 article EN cc-by-nc Journal of Cancer 2024-01-01

ALK rearrangements are rarely documented in superficial soft tissue neoplasms exhibiting an infantile fibrosarcoma-like spindle cell tumor (IFS) pattern or stromal, resembling Neurotrophic Tyrosine Kinase Receptor( NTRK )rearranged tumors. Here, we present two cases of pediatric cutaneous tumors with IFS pattern, which fusions involving related partner genes were identified. The both demonstrated similar morphology and consisted ovoid cells infiltrative boundaries. exhibited either a...

10.3389/fonc.2025.1516491 article EN cc-by Frontiers in Oncology 2025-05-29

A simple and ultra-sensitive method based on HG-SCGD-AES was developed for determination inorganic arsenic valence.

10.1039/c7ja00228a article EN Journal of Analytical Atomic Spectrometry 2017-01-01
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