Guilherme Pinheiro Machado

ORCID: 0000-0002-5514-2562
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About
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Research Areas
  • Acute Myocardial Infarction Research
  • Healthcare during COVID-19 Pandemic
  • Coronary Interventions and Diagnostics
  • Healthcare Regulation
  • Ultrasound in Clinical Applications
  • Cardiac Imaging and Diagnostics
  • Venous Thromboembolism Diagnosis and Management
  • Ultrasound and Hyperthermia Applications
  • Inflammatory Biomarkers in Disease Prognosis
  • Vascular Procedures and Complications
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Arrest and Resuscitation
  • Central Venous Catheters and Hemodialysis
  • Radiation Dose and Imaging
  • Hemodynamic Monitoring and Therapy
  • Adipokines, Inflammation, and Metabolic Diseases
  • Public Health in Brazil
  • Cardiac Valve Diseases and Treatments
  • Atherosclerosis and Cardiovascular Diseases
  • Biomarkers in Disease Mechanisms
  • Laser Applications in Dentistry and Medicine
  • Musculoskeletal pain and rehabilitation
  • Respiratory Support and Mechanisms
  • Stoma care and complications
  • Hospital Admissions and Outcomes

Hospital de Clínicas de Porto Alegre
2008-2025

Hospices Civils de Lyon
2025

Universidade Federal do Rio Grande do Sul
2016-2024

Discovery Air (Canada)
2023

Fundação Universitária de Cardiologia
2022

GTx (United States)
2018-2019

University of Rio Grande and Rio Grande Community College
2018-2019

Universidade de Caxias do Sul
2011-2017

St Thomas' Hospital
1976

Bristol Royal Infirmary
1976

In animal and clinical trials low-level laser therapy (LLLT) using red, infrared mixed wavelengths has been shown to delay the development of skeletal muscle fatigue. However, parameters employed in these studies do not allow a conclusion as which wavelength range is better delaying With this perspective mind, we compared effects red LLLT on A randomized double-blind placebo-controlled crossover trial was performed ten healthy male volunteers. They were treated with active LLLT, (660 or 830...

10.1007/s10103-011-0957-3 article EN cc-by-nc Lasers in Medical Science 2011-07-21

Interleukin-6 (IL-6) is an inflammation-related cytokine associated with elevated risk of cardiovascular events. In a previous study, we demonstrated that increased IL-6 was predictive sub-clinical atherosclerotic coronary disease in intermediate-risk patients undergoing angiography. the present investigated whether serum events high-risk patients.In this observational consecutive referred for elective angiography due to stable chest pain/myocardial ischemia had measured immediately before...

10.1186/s13098-022-00891-0 article EN cc-by Diabetology & Metabolic Syndrome 2022-08-26

Background: Early risk stratification is essential for in-hospital management of ST-segment–elevation myocardial infarction. Acute heart failure confers a worse prognosis, and although lung ultrasound (LUS) recommended as first-line test to assess pulmonary congestion, it has never been tested in this setting. Our aim was evaluate the prognostic ability admission LUS patients with Methods: protocol consisted 8 scanning zones performed before primary percutaneous coronary intervention by an...

10.1161/circimaging.119.010269 article EN Circulation Cardiovascular Imaging 2020-06-01

Summary Introduction The diagnostic accuracy of gastric ultrasound in children has not been assessed thoroughly. We aimed to determine the sensitivity and specificity a qualitative examination antrum supine 45° semi‐recumbent position clinical algorithm for detecting fluid volume > 1.25 ml.kg ‐1 , reported represent an ‘at‐risk stomach’ pulmonary aspiration. Methods conducted prospective, observer‐blinded, randomised trial healthy fasted according current pre‐operative guidelines. An...

10.1111/anae.16539 article EN Anaesthesia 2025-01-07

Background: Patients with long coronary lesions undergoing primary percutaneous intervention (pPCI) have higher rates of adverse clinical events. Both stent length and overlap are associated worse outcomes; however, data comparing very (VLS) to overlapping stents (OSs) limited, particularly during pPCI. This study aimed compare the impact a single VLS versus ≥2 OSs on outcomes in multicenter registry patients Methods: included ST-segment elevation myocardial infarction (STEMI) who underwent...

10.1097/hpc.0000000000000371 article EN Critical Pathways in Cardiology A Journal of Evidence-Based Medicine 2025-02-21

Transcatheter aortic valve implantation (TAVI) has been established as the treatment of choice for severe stenosis in high risk well patients above 75 years-old all spectrums. Despite its worldwide adoption, implementation lower-middle-income countries such Brazilian public health system (SUS, acronym Portuguese) is incipient. This study aimed to evaluate TAVI exclusively within SUS patients. was prospective cohort a tertiary hospital southern Brazil. All who underwent between 2018 and 2024...

10.1097/hpc.0000000000000387 article EN Critical Pathways in Cardiology A Journal of Evidence-Based Medicine 2025-02-27

Background: Left ventricular end-diastolic pressure (LVEDP) is related to dysfunction and increased retrograde pulmonary capillary pressure. Lung ultrasound (LUS) a sensitive easy-to-use method for assessment of congestion. Both methods have shown prognostic value in patients with ST-segment–elevation myocardial infarction. Our aim was evaluate the correlation between LVEDP bedside LUS compare their undergoing primary percutaneous coronary intervention. Methods: Prospective cohort study...

10.1161/circimaging.120.011641 article EN Circulation Cardiovascular Imaging 2021-04-01

Background Elevated neutrophil-to-lymphocyte ratio (NLR) is an indirect marker of inflammation, and associated with adverse clinical outcomes in patients ST-segment elevation myocardial infarction (STEMI). The aim this study was to investigate the usefulness NLR predict procedural events who underwent primary percutaneous coronary intervention (PCI). Patients methods Consecutive STEMI PCI were divided into low high NLR, whereas defined as value above 75° percentile (≥9.45). occurrence...

10.1097/mca.0000000000000671 article EN Coronary Artery Disease 2018-10-17

Abstract Background Guide catheter extensions (GCEs) increase support and facilitate equipment delivery, but aggressive instrumentation may be associated with a higher risk of complications. Aim Our aim was to assess the impact GCEs on procedural success complications in patients submitted chronic total occlusion (CTO) percutaneous coronary intervention (PCI). Methods We analyzed data from multicenter LATAM CTO Registry. Procedural defined as <30% residual stenosis TIMI 3 distal flow....

10.1002/ccd.30987 article EN Catheterization and Cardiovascular Interventions 2024-03-01

Resumo Fundamento O padrão-ouro atual dos stents farmacológicos (SF) coronários consiste em ligas metálicas com hastes mais finas e polímeros bioabsorvíveis. Objetivos Nosso objetivo foi comparar um stent eluidor de sirolimus ultrafinas (Inspiron®) outras plataformas SF terceira geração pacientes infarto do miocárdio supradesnivelamento segmento ST (IAMCSST) submetidos à intervenção coronária percutânea (ICP) primária. Métodos Analisamos dados registro multicêntrico IAMCSST centros...

10.36660/abc.20220594 article PT cc-by-nc Arquivos Brasileiros de Cardiologia 2023-01-01

Objetivo: Analisar prevalência, localização anatômica, situação de origem e ocorrência, afastamento severidade das lesões em atletas Jiu-Jitsu. Métodos: Participaram deste trabalho 308 atletas. O instrumento avaliação consistiu na aplicação um questionário fechado que foi respondido pelos lutadores. Resultados: As regiões anatômicas mais acometidas foram o joelho (28,40%), ombro (15,60%) cotovelo (10,40%), 42,80% ocorreram quando atleta recebeu golpe, 15,60% aplicaram golpe. A maior parte...

10.5585/conssaude.v11n1.3033 article PT ConScientiae Saúde 2012-03-30

Several studies have shown that women are usually undertreated and worse outcomes after ST-segment elevation myocardial infarction (STEMI), hence the need to investigate questions related sex in Brazil better deal with problem.To determine whether female is still associated adverse events a contemporary cohort of patients STEMI undergoing primary percutaneous coronary intervention (pPCI).This was prospective study submitted pPCI tertiary university hospital between March 2011 December 2021....

10.36660/abc.20220673 article PT cc-by-nc Arquivos Brasileiros de Cardiologia 2023-01-01

Red cell distribution width (RDW) is an indirect marker of inflammation and independent predictor long-term mortality. The aim this study was to determine RDW values in patients with ST-elevation acute myocardial infarction (STEMI) submitted primary percutaneous coronary intervention (PCI) evaluate its association adverse outcomes. We measured STEMI before undergoing PCI divided into low high RDW. Patients were followed up 3 years after their discharge for the occurrence in-hospital,...

10.1097/hpc.0000000000000196 article EN Critical Pathways in Cardiology A Journal of Evidence-Based Medicine 2019-09-02

Introduction:Early reperfusion therapy is crucial in patients with ST-elevation myocardial infarction (STEMI).Off-hours hospital presentation may increase the time from pain to coronary reperfusion, and it be responsible for increased cardiovascular outcomes.The aim of this study was compare effect different times (on-and off-hours) on early mortality major outcomes STEMI who underwent primary percutaneous intervention (PCI). Methods:We have included consecutive PCI between April 2011...

10.4322/2357-9730.75542 article EN cc-by Clinical & Biomedical Research 2018-01-01

Objective As a parallel to the radial approach for left heart catheterisation, forearm veins may be considered performance of right catheterisation. However, data regarding application this technique under ultrasound guidance are scarce. The current study aims demonstrate feasibility catheterisation through ultrasound-guided antecubital venous in highly heterogeneous population usually referred Methods Data from consecutive catheterisations performed at an academic centre Brazil, between...

10.1136/openhrt-2019-001181 article EN cc-by-nc Open Heart 2020-02-01
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