A5018951657- Sports Performance and Training
- Muscle metabolism and nutrition
- Exercise and Physiological Responses
- Muscle Physiology and Disorders
- Cardiovascular and exercise physiology
- Sports injuries and prevention
- Genetics and Physical Performance
- Muscle activation and electromyography studies
- Genetic Neurodegenerative Diseases
- Occupational Health and Performance
- Congenital Heart Disease Studies
- Body Composition Measurement Techniques
- Adipose Tissue and Metabolism
- Cardiomyopathy and Myosin Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Ischemia and Reperfusion
- Nutrition and Health in Aging
- Thermoregulation and physiological responses
- Chromosomal and Genetic Variations
- Physical Activity and Health
- Diet and metabolism studies
- Cardiac Arrest and Resuscitation
- Veterinary medicine and infectious diseases
- RNA and protein synthesis mechanisms
- GDF15 and Related Biomarkers
Auburn University
2016-2022
Applied Sciences Laboratory (United States)
2017-2022
LaGrange College
2019-2021
Edith Cowan University
2020
Lindenwood University
2020
Mercyhurst University
2020
Coastal Carolina University
2020
Conway School of Landscape Design
2020
University of Rhode Island
2020
Charles Darwin University
2020
Skeletal muscle is highly adaptable and has consistently been shown to morphologically respond exercise training. growth during periods of resistance training traditionally referred as skeletal hypertrophy, this manifests increases in mass, thickness, area, volume, fiber cross-sectional area (fCSA). Delicate electron microscopy biochemical techniques have also used demonstrate that promotes ultrastructural adaptations within fibers. Decades research physiology promulgated a widespread...
We sought to determine the effects of L-leucine (LEU) or different protein supplements standardized LEU (~3.0 g/serving) on changes in body composition, strength, and histological attributes skeletal muscle adipose tissue. Seventy-five untrained, college-aged males (mean ± standard error mean (SE); age = 21 1 years, mass 79.2 0.3 kg) were randomly assigned an isocaloric, lipid-, organoleptically-matched maltodextrin placebo (PLA, n 15), (n 14), whey concentrate (WPC, 17), hydrolysate (WPH,...
We sought to identify biomarkers which delineated individual hypertrophic responses resistance training. Untrained, college-aged males engaged in full-body training (3 d/wk) for 12 weeks. Body composition via dual x-ray absorptiometry (DXA), vastus lateralis (VL) thickness ultrasound, blood, VL muscle biopsies, and three-repetition maximum (3-RM) squat strength were obtained prior (PRE) following (POST) weeks of K-means cluster analysis based on changes identified LOW [n = 17; change...
Hypertrophy can be operationally defined as an increase in the axial cross-sectional area of a muscle fiber or whole muscle, and is due to increases size pre-existing fibers. desired outcome many sports. For some athletes, muscular bulk and, conceivably, accompanying strength/power, are desirable attributes for optimal performance. Moreover, bodybuilders other physique athletes judged part on their size, with placings predicated overall magnitude lean mass. In cases, even relatively small...
Cellular adaptations that occur during skeletal muscle hypertrophy in response to high-volume resistance training are not well-characterized. Therefore, we sought explore how actin, myosin, sarcoplasmic protein, mitochondrial, and glycogen concentrations were altered individuals exhibited mean fiber cross-sectional area (fCSA) following 6 weeks of training. Thirty previously resistance-trained, college-aged males (mean ± standard deviation: 21±2 years, 5±3 years) had vastus lateralis (VL)...
Limited evidence exists regarding differentially expressed biomarkers between previously-trained low versus high hypertrophic responders in response to resistance training. Herein, 30 college-aged males (training age 5 ± 3 years; mean SD) partook 6 weeks of high-volume Body composition, right leg vastus lateralis (VL) biopsies, and blood were obtained prior training (PRE) at the 3-week (W3) 6-week time points (W6). The 10 lowest (LOW) highest (HIGH) clustered based upon a composite...
Schoenfeld, BJ, Alto, A, Grgic, J, Tinsley, G, Haun, CT, Campbell, BI, Escalante, Sonmez, GT, Cote, Francis, and Trexler, ET. Alterations in body composition, resting metabolic rate, muscular strength, eating behavior response to natural bodybuilding competition preparation: A case study. J Strength Cond Res 34(11): 3124-3138, 2020-We carried out a prospective study high-level amateur male bodybuilder throughout preparation for 4 competitions during the ensuing postcontest recovery period....
We sought to examine how 12 weeks of resistance exercise training (RET) affected skeletal muscle myofibrillar and sarcoplasmic protein levels along with markers mitochondrial physiology in high versus low anabolic responders.Untrained college-aged males were classified as responders the top 25th percentile (high-response cluster (HI); n = 13, dual x-ray absorptiometry total body mass change (Δ) +3.1 ± 0.3 kg, Δ vastus lateralis (VL) thickness +0.59 0.05 cm, fiber cross sectional area +1,426...
Recent evidence suggests that resistance training with light or heavy loads to failure results in similar adaptations. Herein, we compared how both modalities affect the molecular, neuromuscular, and recovery responses following exercise. Resistance-trained males (mean ± SE: 22 2 years, 84.8 9.0 kg, 1.79 0.06 m; n = 15) performed a crossover design of four sets leg extensor exercise at 30% (light RE) 80% (heavy one repetition maximum (1RM) failure, RE 1 week later. Surface electromyography...
We examined hypertrophic outcomes of weekly graded whey protein dosing (GWP) vs. (WP) or maltodextrin (MALTO) dosed once daily during 6 weeks high-volume resistance training (RT). College-aged resistance-trained males (training age = 5 ± 3 years; mean SD) performed RT wherein frequency was d/week and each session involved 2 upper- lower-body exercises (10 repetitions/set). Volume increased from 10 sets/exercise (week 1) to 32 6), which is the highest volume investigated in this timeframe....
It has been proposed that superior muscle hypertrophy may be obtained by training muscles predominant in type I fibers with lighter loads and those II heavier loads. Purpose To evaluate longitudinal changes strength of the soleus (a predominantly slow-twitch muscle) gastrocnemius (muscle a similar composition slow fast-twitch fibers) when subjected to light (20–30 repetition maximum) heavy (6–10 load plantarflexion exercise. Methods The study employed within-subject design whereby 26...
The current study investigated how bovine milk exosomes affected rotarod performance and biomarkers of skeletal muscle physiology in young, growing rats. Twenty-eight-day Fisher 344 rats were provided an AIN-93G-based diet for four weeks that either remained unadulterated (exosome RNA-sufficient (ERS; n=12)) or was sonicated RNA-depleted (ERD; n=12)). Prior to (PRE) on the last day intervention (POST), animals tested maximal performance. Following feeding period, gastrocnemius analyzed at...
We aimed to investigate the effects of resistance training (RT) combined with no-load isometric actions (iso-holds) during inter-set recovery period versus RT that involves passive rest on muscular strength, hypertrophy, and endurance in resistance-trained men. Twenty-seven male volunteers were randomly assigned either a traditional group (TRAD) performed hypertrophy-oriented routine intervals spent passively (n = 13) or supplemented iso-holds (ISO) for working muscle between each set 14)....
Resistance training volume, determined by the number of sets performed (set-volume) is considered one key variables in promoting muscle hypertrophy. To better guide resistance exercise prescription for weekly per-muscle purpose this paper to provide evidence-based considerations set-volume ratios between multi-joint (MJ) and single-joint (SJ) exercises so that practitioners can manage volume program design. We analyzed topic from three primary areas focus: (1) biomechanical physiological...
Resistance training generally increases skeletal muscle hypertrophy, whereas aging is associated with a loss in mass. Interestingly, select studies suggest that aging, as well resistance training, may lead to reduction the abundance of myofibrillar (or contractile) protein (per mg tissue). Proteomic interrogations have also demonstrated weeks months appreciable alterations proteome. Given this evidence, purpose small pilot study was examine total sarcoplasmic concentrations wet muscle) from...
Several published protocols exist for isolating contractile or myofibrillar (MF) proteins from skeletal muscle, however, achieving complete resuspension of the myofibril pellet can be technically challenging. We performed several previously MF isolation methods with intent determining which method was most suitable protein and solubilization. Here, we provide an optimized protocol to isolate sarcoplasmic solubilized fractions mammalian muscle downstream assays.
Alterations in transcriptional and translational mechanisms occur during skeletal muscle aging such changes may contribute to age-related atrophy. Herein, we examined markers related global output (i.e., myonuclear number, total mRNA RNA pol II levels), efficiency [i.e., eukaryotic initiation elongation factor levels protein synthesis (MPS) levels] capacity (ribosome density) the slow-twitch soleus fast-twitch plantaris muscles of male Fischer 344 rats aged 3, 6, 12, 18, 24 months (n = 9-10...
We investigated the effects of whey protein (WP) supplementation on body composition and physical performance in soldiers participating Army Initial Entry Training (IET). Sixty-nine, male United States volunteered for with either twice daily (WP, 77 g/day protein, ~580 kcal/day; n = 34, age 19 ± 1 year, height 173 6 cm, weight 73.4 12.7 kg) or energy-matched carbohydrate (CHO) drinks (CHO, 127 carbohydrate, 35, 5 72.3 10.9 eight weeks during IET. Physical was evaluated using Fitness Test two...
We sought to compare the effects of external pneumatic compression (EPC) and sham when used concurrently with resistance training on performance-related outcomes molecular measures related recovery.Twenty (N = 20) resistance-trained male participants (aged 21.6±2.4 years) were randomized balanced or EPC intervention groups. The protocol consisted 3 consecutive days heavy, voluminous back squat exercise followed by EPC/sham treatment (Days2-4) recovery (Days5-7) only Days5-6. On Day1 (PRE),...