Abstract Grimace scales have been used for pain assessment in different species. This study aimed to develop and validate the Feline Scale (FGS) detect naturally-occurring acute pain. Thirty-five client-owned twenty control cats were video-recorded undisturbed their cages a prospective, case-control study. Painful received analgesic treatment videos repeated one hour later. Five action units (AU) identified: ear position, orbital tightening, muzzle tension, whiskers change head position....

Abstract Animal sentience refers to the capacity of animals feel both positive and negative emotions including that pain. As veterinary health professionals, we have a medical ethical duty mitigate suffering from pain best our ability. In 2014, first Global Pain Council World Small Veterinary Association (WSAVA) Guidelines for Recognition, Assessment Treatment was published remains this day one most relevant widespread documents its kind. The 2022 WSAVA Management evolves document with...

Continuous product monitoring post approval builds on the knowledge gained during clinical studies to aid in understanding a product's safety and efficacy profile. Pharmacovigilance reporting of medicinal might be influenced by several factors including duration market, geographical region veterinary practices. The goals this report are present global data accrued for bedinvetmab, first monoclonal antibody canine osteoarthritis, explore patterns globally across major markets. Adverse event...

The Feline Grimace Scale (FGS) is a facial expression-based scoring system for acute pain assessment in cats with reported validity using image assessment. aims of this study were to investigate the clinical applicability FGS real-time when compared assessment, and evaluate influence sedation surgery on scores cats.Sixty-five female (age: 1.37 ± 0.9 years body weight: 2.85 0.76 kg) included prospective, randomized, trial. Cats sedated intramuscular acepromazine buprenorphine. Following...

Objectives This study aimed to investigate if cat caregivers could reliably assess acute pain using the Feline Grimace Scale (FGS), and participant demographics affect scores. Methods An online survey in English Spanish was advertised by International Cat Care other platforms (March–May 2021) convenience sampling. Eligible participants were >18 years old non-veterinary health professionals. Participants a group of eight veterinarians scored 10 images cats with different levels pain. Data...

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and effective for the management of pain in cats. These Guidelines will support veterinarians decision-making around prescribing NSAIDs situations chronic pain, to minimise adverse effects optimise management. Information is provided on mechanism action, indications use, screening prior prescription, use presence comorbidities, monitoring efficacy, avoidance effects.

Objectives The aim of this study was to evaluate the analgesic efficacy intraperitoneal (IP) bupivacaine in cats undergoing ovariohysterectomy (OVH). Methods Forty-five were included a randomized, prospective, blinded after owners’ written consent obtained. anesthetic protocol acepromazine–buprenorphine–propofol–isoflurane. A ventral midline incision made and (n = 15/group) administered either IP saline 0.9% (negative positive control groups; NG PG, respectively) or (2 mg/kg; group; BG)....

Objectives The aim of the study was to evaluate analgesic efficacy gabapentin–buprenorphine in comparison with meloxicam–buprenorphine or buprenorphine alone, and correlation between two pain-scoring systems cats. Methods Fifty-two adult cats were included a randomized, controlled, blinded study. Anesthetic protocol acepromazine–buprenorphine–propofol–isoflurane. group (GBG, n = 19) received gabapentin capsules (50 mg PO) (0.02 mg/kg IM). (MBG, 15) meloxicam (0.2 SC), placebo (PO). (BG, 18)...

Adequate pain relief is usually achieved with the simultaneous use of two or more different classes analgesics, often called multimodal analgesia. The purpose this article to highlight perioperative analgesia and need individualize treatment plan based on presenting condition, adjust it response for a given patient. This case series presents alleviation acute in three cats undergoing major surgical procedures. These cases involved administration analgesic drugs, including opioids,...

Objectives This study aimed to (1) compare outcome assessments in normal and osteoarthritic cats (2) evaluate the analgesic efficacy of tramadol feline osteoarthritis (OA), a prospective, randomised, blinded, placebo-controlled, crossover design. Methods Twenty were included after clinical examination, blood work full body radiographs performed. In Phase 1, differentiate (n = 5; i.e. exempt any radiographic sign OA) from OA 15) cats. 2, treated twice daily with placebo (PG: cornstarch 15 mg)...

Background The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception a high-concentration formulation buprenorphine (Simbadol™) in cats. Methods Six healthy cats (4.9 ± 0.7 kg) were included prospective, randomized, blinded, crossover study. Simbadol™ (1.8 mg mL-1) administered by subcutaneous (SC; 0.24 kg-1), intravenous (IV; 0.12 kg-1) or buccal (OTM; route administration thresholds (TT) compared with saline group (SAL)....

Pain is the leading cause of animal suffering, hence importance validated tools to ensure its appropriate evaluation and treatment. We aimed test psychometric properties short form Unesp-Botucatu Feline Scale (UFEPS-SF) in eight languages.The original scale was condensed from ten four items. The content validation performed by five specialists veterinary anesthesia analgesia. English version translated back-translated into Chinese, French, German, Italian, Japanese, Portuguese Spanish fluent...

Objectives This study compared an opioid-free injectable anaesthetic protocol with or without multimodal analgesia in kittens undergoing ovariohysterectomy. Methods In this prospective, randomised, blinded, clinical trial, 29 healthy (mean ± SD weight 1.55 0.46 kg; aged 10 weeks to 6 months) were included. Anaesthesia was performed intramuscular injection of ketamine (4 mg/kg), dexmedetomidine (40 μg/kg) and midazolam (0.25 mg/kg). the group (MMG), cats (n = 14) received meloxicam (0.1 mg/kg...

Objectives This randomised, prospective, masked clinical trial evaluated the postoperative analgesic efficacy of an ultrasound-guided transversus abdominis plane block (TAPB) with bupivacaine in cats undergoing ovariohysterectomy. Methods Thirty-two healthy adult female elective ovariohysterectomy were randomised to undergo TAPB (treatment group [TG], n = 16) vs placebo (control [CG], addition preoperative analgesia buprenorphine (0.02 mg/kg IM). All patients received a general anaesthetic...

Chronic pain is a feline health and welfare issue. It has negative impact on quality of life impairs the owner-cat bond. can exist by itself or may be associated with disease and/or injury, including osteoarthritis (OA), cancer, oral periodontal disease, among others.

This study aimed to evaluate the inter-rater reliability of Feline Grimace Scale (FGS) in cats undergoing dental extractions and effects caregiver's presence on FGS scores. Twenty-four (6 ± 3.3 years old; 4.9 1.7 kg) oral treatment were included a prospective, blinded, randomized, clinical study. They underwent under general anesthesia (acepromazine-hydromorphone-propofol-isoflurane-meloxicam-local anesthetic blocks) at day 1 discharged 6. Images cat faces captured from video recordings with...