A5060161447- Elasticity and Material Modeling
- Coronary Interventions and Diagnostics
- Connective tissue disorders research
- Cerebrovascular and Carotid Artery Diseases
- Tendon Structure and Treatment
- Cardiovascular Health and Disease Prevention
- Cellular Mechanics and Interactions
- Collagen: Extraction and Characterization
- Manufacturing Process and Optimization
- Optical measurement and interference techniques
- Operations Management Techniques
- Transport and Logistics Innovations
St. Anne's University Hospital Brno
2020-2025
University Hospital Brno
2020-2025
Masaryk University
2020-2024
Residual stresses are considered as a significant factor influencing the stress-states in arteries. These typically observed through opening angle of radially cut artery segment, often regarded primary descriptor their stress-free state. However, experimental evidence regarding states different layers is scarce. In this study, two protocols, each employing layer-separating sequences, were performed on 17 human common carotid arteries; differences between both protocols found statistically...
Most frequently used structure-based constitutive models of arterial wall apply assumptions on two symmetric helical (and dispersed) fibre families which, however, are not well supported with histological findings where collagen seldom found. Moreover, bimodal distributions directions may originate also from their waviness combined ignoring differences between local and global orientations. In contrast, if the model parameters identified without information directions, resulting mean angles...
A novel method for semiautomated assessment of directions collagen fibers in soft tissues using histological image analysis is presented. It based on multiple rotated images obtained via polarized light microscopy without any additional components, i.e., with just two polarizers being either perpendicular or nonperpendicular (rotated). This arrangement breaks the limitation 90° periodicity intensity and evaluates in-plane fiber orientation over whole 180° range accurately quickly. After...
The paper deals with the impact of chosen geometric and material factors on maximal stresses in carotid atherosclerotic plaque calculated using patient-specific finite element models. These are believed to be decisive for vulnerability but all applied models suffer from inaccuracy input data, especially when obtained vivo only. One hundred computational based ex MRI used investigate wall thickness, slice lipid core fibrous tissue stiffness, media anisotropy peak cap stresses. investigated...
Abstract Residual stresses are considered as a significant factor influencing the stress-states in arteries. These typically observed through opening angle of radially cut artery segment, often regarded primary descriptor their stress-free state. However, experimental evidence regarding states different layers is scarce. In this study, two protocols, each employing layer-separating sequences, were performed on 17 human common carotid arteries; differences between both protocols found...
A novel method for automated assessment of directions collagen fibers in soft tissues is presented. It based on multiple rotated images obtained via polarized light microscope with perpendicular and inclined polarizers thus it breaks the limitation 90° periodicity intensity evaluates fiber orientation over whole 180° range accurately quickly. After having verified method, we used histological specimens porcine Achilles tendon aorta to validate proposed algorithm lower number needed...