- Natural Antidiabetic Agents Studies
- Synthesis and pharmacology of benzodiazepine derivatives
- Chemical synthesis and alkaloids
- Cyclization and Aryne Chemistry
- Phytochemicals and Antioxidant Activities
- Asymmetric Hydrogenation and Catalysis
- Phytochemical and Pharmacological Studies
- Hibiscus Plant Research Studies
- Synthesis of β-Lactam Compounds
- Synthesis and Catalytic Reactions
- Graphene and Nanomaterials Applications
- Essential Oils and Antimicrobial Activity
- Coconut Research and Applications
University of Coimbra
2023-2024
Plateau State University
2023
Abstract ‐ Several novel organocatalysts derived from β‐ and γ‐lactam‐fused thiazolidines L ‐phenylalanine‐based were efficiently synthetized. These organocatalysts, as well other previously developed thiazolidine‐derived thioureas, tested in the asymmetric one‐pot Neber reaction of β‐ketoxime‐1 H ‐tetrazoles towards chiral 2‐(tetrazol‐5‐yl)‐ 2H ‐azirines. The results obtained when using thioureas only differing lactam ring size demonstrate that presence 6β‐lactam catalysts is a requirement...
A new selective synthetic approach to indole derivatives bearing a tetrazole moiety has been developed. Arynes, generated in situ from o-(trimethylsilyl)aryl triflates and KF, reacted smoothly with 2-(2-benzyl-2H-tetrazol-5-yl)-2H-azirines give 3-(2-benzyl-2H-tetrazol-5-yl)-indole high selectivity. Deprotection of the gave 3-(1H-tetrazol-5-yl)-indole derivatives.
3D graphene materials are carbon nanomaterials that gaining significant attention recently due to their unique properties. They incredibly strong, have electrical, thermal optical and chemical properties make them stand out the preferred of choice in material sciences. These gained since 2004 now been used for various applications including medical uses. In this review, we explored some recent advances research these materials, synthesis methods several applications. Several techniques being...