Iván Lylyk
A5043699838- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Moyamoya disease diagnosis and treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Aortic Disease and Treatment Approaches
- Acute Ischemic Stroke Management
- Peripheral Artery Disease Management
- Cardiovascular and Diving-Related Complications
- Aortic aneurysm repair treatments
- Retinal Imaging and Analysis
- Neurological Complications and Syndromes
- Intracerebral and Subarachnoid Hemorrhage Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Connective tissue disorders research
- Pituitary Gland Disorders and Treatments
- Retinal and Optic Conditions
- Vascular Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Spinal Fractures and Fixation Techniques
- Spinal Dysraphism and Malformations
- Venous Thromboembolism Diagnosis and Management
University of Pennsylvania
2025
Instituto Cardiovascular de Rosario
2018-2024
Neuroscience Institute
2022
Brigham and Women's Hospital
2022
Electronics for Imaging (United States)
2022
Medico
2022
University of Massachusetts Chan Medical School
2016
Background Flow-diverter stents (FDS) have become the standard of care for a wide range intracranial aneurysms, but their efficacy/safety in context recurrent/recanalized aneurysms following stent-assisted coiling (SAC) is not well established. We evaluate outcomes FDS retreatment large multicenter cohort. Methods retrospectively analyzed data from 118 patients across 22 institutions who underwent recurrent/persistent after SAC (2008–22). The primary outcome was angiographic occlusion status...
Abstract BACKGROUND Prospective studies have established the safety and efficacy of Pipeline TM Embolization Device (PED; Medtronic) for treatment intracranial aneurysms (IA). OBJECTIVE To investigate long-term outcomes from Devices Treatment Intracranial Aneurysms (PEDESTRIAN) Registry. METHODS The PEDESTRIAN Registry data were retrospectively reviewed, which included patients (March 2006 to July 2019) with complex IAs treated PED. Patients unfavorable anatomy and/or recurrence following...
Background The Woven EndoBridge (WEB) device is frequently used for the treatment of intracranial aneurysms. Postoperative management, including use aspirin, varies among clinicians and institutions, but its impact on outcomes WEB has not been thoroughly investigated. Methods This was a retrospective, multicenter study involving 30 academic institutions in North America, South Europe. Data from 1492 patients treated with were included. Patients categorized into two groups based their...
Endovascular interventions are increasingly becoming the preferred approach for treating strokes and cerebral artery diseases. These procedures rely on sophisticated angiographical imaging guidance, which encounters challenges because of limited contrast spatial resolution. Achieving a more precise visualization underlying arterial pathology neurovascular implants is crucial accurate procedural decision-making. In human study involving 32 patients, we introduced clinical application...
Objective The p48 is a low-profile, intermediate-porosity flow diverter. phenox GmbH-trademarked hydrophilic polymer coating (pHPC) that has been shown in vitro to reduce the thrombogenicity of nitinol device surfaces. We performed present study determine whether p48_HPC can be implanted using prasugrel alone. Methods retrospectively identified all patients who were treated with from January 2017 December 2018 (n = 5) and underwent single antiplatelet therapy (SAPT) prasugrel. P2Y12...
<h3>BACKGROUND AND PURPOSE:</h3> Treatment of wide-neck bifurcation aneurysms using endovascular therapy is still challenging even with the development treatment devices. The purpose this investigation was to assess safety and efficacy a Woven EndoBridge (WEB) device for aneurysms. <h3>MATERIALS METHODS:</h3> All patients treated WEB at our institution between May 2009 November 2016 were retrospectively evaluated. Clinical imaging evaluation, aneurysm occlusion status, modified Rankin scale...
Surgical ventriculoperitoneal shunting remains standard treatment for communicating hydrocephalus, despite persistently elevated infection and revision rates. A novel minimally invasive endovascular cerebrospinal fluid (CSF) shunt was developed to mimic the function of arachnoid granulation which passively filters CSF from central nervous system back into intracranial venous sinus network. The is deployed via a femoral transvenous approach across dura mater cerebellopontine angle cistern. An...
Vascular remodeling in response to implantation of a tissue engineering scaffold such as flow diverter (FD) leads the cure intracranial aneurysms. We hypothesize that vascular is dependent on FD design, and CD34+ progenitor cells play an important role endothelialization implant.Sixteen rabbit aneurysms were randomly treated with two different single-layer braided FDs made cobalt-chrome alloys. The FD-48 FD-72 devices had 48 72 wires, respectively. Aneurysm occlusion rate was assessed during...
Background The Woven EndoBridge (WEB) device was explicitly designed for wide-neck intracranial bifurcation aneurysms. Small-scale reports have evaluated the off-label use of WEB devices treatment sidewall aneurysms, with promising outcomes. Purpose To compare angiographic and clinical outcomes aneurysms compared Materials Methods A retrospective review WorldWideWEB Consortium, a synthesis databases spanning from January 2011 to June 2021 at 22 academic institutions in North America, South...
There is considerable overlap of contributors to cardiovascular disease and the development age-related macular degeneration (AMD). Compromised ocular microcirculation due aging vascular contribute retinal dysfunction vision loss. Decreased choroidal perfusion evident in eyes with dry AMD thought play a role pigment epithelial dysfunction, rate geographic atrophy, neovascularization. The aim study was demonstrate that correlated compromised blood flow pathway show OA angioplasty as potential...
The Woven EndoBridge (WEB) device has Food and Drug Administration approval for treatment of wide-necked intracranial bifurcation aneurysms. WEB been shown to result in adequate occlusion aneurysms overall, but its usefulness the individual locations evaluated separately only few case series, which were limited by small sample sizes.To compare angiographic clinical outcomes after at various locations, including anterior communicating artery (AComA), cerebral (ACA) distal AComA, basilar tip,...
OBJECTIVE Tobacco smoking is among the factors known to significantly augment risk of untreated intracranial aneurysm (IA) growth and rupture. Smoking appears have a variable effect on different endovascular treatment modalities. The impact safety, efficacy, outcomes Woven EndoBridge (WEB) device use for wide-neck IAs has not been evaluated. This study aimed investigate WEB devices by status. METHODS A retrospective multicenter analysis was conducted data patients from 36 sites worldwide...
Abstract The Woven EndoBridge (WEB) device is FDA-approved for the treatment of bifurcation aneurysms. Despite its wide popularity, it has been under scrutiny association with potential aneurysm recanalization and retreatment due to shape modification. This study aims analyze modification rate WEB devices identify factors associated this phenomenon, as well correlation retreatment. We conducted a retrospective review WorldWide Consortium database, including adult patients treated...
Abstract While the Woven EndoBridge (WEB) device has transformed treatment of wide-neck intracranial aneurysms, incomplete occlusion remains a significant challenge requiring better understanding contributing factors. A retrospective analysis was conducted on multicenter data from patients who underwent WEB for aneurysms between January 2011 and December 2022. Using machine learning models, Cox regression, time-stratified analyses, we evaluated factors associated with persistent occlusion,...
The Woven EndoBridge (WEB) device is a prevalent treatment for intracranial aneurysms. While many studies have assessed the obliteration rate post-WEB embolization, few focused on long-term outcomes in partially thrombosed To assess whether aneurysms are at higher risk of recurrence or retreatment following WEB embolization compared with non-thrombosed We evaluated data from 22 academic institutions, focusing previously untreated cerebral treated device. Logistic regression was utilized to...
The eShunt System (CereVasc, Charlestown, Massachusetts, USA) is a novel endovascularly implantable cerebrospinal fluid shunt that has recently emerged as an alternative strategy for the treatment of communicating hydrocephalus.1 It consists implant and its associated delivery components.2 designed to be implanted via transvenous approach into cerebellopontine angle cistern, mimicking natural physiology arachnoid granulations.3 4 In this technical video 1, we will review key anatomic...
Objective The objective of this study was to report our experience on the use flow diverting stents placed within posterior inferior cerebellar artery (PICA) as a treatment option for aneurysms PICA. Methods Three patients with PICA, both ruptured and unruptured, underwent their placement single diverter in PICA across neck aneurysm. Adjunctive techniques such coiling were not used. We present angiographic clinical follow-up data. Results procedure technical success all cases there no...
The use of flow diverters to treat aneurysms arising from small caliber parent vessels has been reported. This article reports the results first in experiences with p48MW (p48 Movable Wire) humans, a device specifically designed target 1.75-3 mm diameter.This monocentric study retrospectively reviewed prospectively maintained database identify all patients treated between January 2017 and 2019 at this institution. Patient demographics, aneurysm characteristics, angiographic clinical...
The Woven EndoBridge (WEB) device is a novel intrasaccular flow disruptor tailored for bifurcation aneurysms. We aim to describe the degree of aneurysm occlusion at latest follow-up, and rate complications aneurysms treated with WEB stratified according rupture status.Our data were taken from WorldWideWeb Consortium, an international multicenter cohort including patients device. Aneurysms classified into two groups: ruptured unruptured. compared clinical radiologic outcomes both groups....
Abstract The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB in versus small . conducted a retrospective review WorldWide Consortium database, from 2011 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed compare baseline characteristics. A total 898 patients were...