A5039948481- Plant and animal studies
- Insect and Pesticide Research
- Insect and Arachnid Ecology and Behavior
- Alzheimer's disease research and treatments
- Cholinesterase and Neurodegenerative Diseases
- Mitochondrial Function and Pathology
- Signaling Pathways in Disease
- Cancer, Hypoxia, and Metabolism
- Heat shock proteins research
- Hormonal Regulation and Hypertension
- Biochemical Acid Research Studies
- ATP Synthase and ATPases Research
- Glutathione Transferases and Polymorphisms
- Trace Elements in Health
Oregon State University
2020-2025
University of Kansas
2013-2015
Gonzaga University
2015
Pesticide exposures can have detrimental impacts on bee pollinators, ranging from immediate mortality to sub-lethal impacts. Flupyradifurone is the active ingredient in Sivanto™ and sulfoxaflor Transform®. They are both relatively new insecticides developed with an intent reduce negative effects bees, when applied bee-attractive crops. With growing concern regarding pollinator health declines, it important a better understanding of any potential impacts, especially sub-lethal, these...
Amyloid beta (Aβ) binding alcohol dehydrogenase (ABAD) is a cellular cofactor for promoting (Aβ)-mediated mitochondrial and neuronal dysfunction, cognitive decline in transgenic Alzheimer's disease (AD) mouse models. Targeting ABAD may represent novel therapeutic strategy against AD. Here, we report the biological activity of small molecule inhibitors. Using vitro surface plasmon resonance (SPR) studies, synthesized compounds with strong affinities ABAD. Further, these inhibitors (ABAD-4a...
ABSTRACT Male stag beetles possess colossal mandibles, which they wield in combat to obtain access females. As with many other sexually selected weapons, males longer mandibles win more fights. However, variation the functional morphology of these structures, used male‐male combat, is less well understood. In this study, mandible bite force, gape, structural strength, and potential tradeoffs are examined across a wide size range for one species beetle, Cyclommatus metallifer . We found that...
Understanding the distribution of pesticides in floral landscape is critical for land managers and regulators, particularly since identifying where exposure occurs to pesticide mitigation. In this study, we developed a bee-plant network commercial sweet cherry (Prunus avium L.) system surrounding unmanaged habitat. We estimated contamination flowering plants by trapping pollen from honey bee colonies, plant species origin pollen, relating non-Apis visitation toxicity detections. Over 90...
17β-hydroxysteroid dehydrogenase type 10 (HSD10) has been shown to play a protective role in cells undergoing stress. Upregulation of HSD10 under nutrient-limiting conditions leads recovery homeostatic state. Across disease states, increased levels can have profound and varied impact, such as beneficial Parkinson's harmful Alzheimer's disease. Recently, overexpression observed some prostate bone cancers, consistently correlating with poor patient prognosis. As the cancer remains...
Analysis of trapped honey bee pollen for pesticide residues is the most widely used method monitoring amount entering colonies and its change over time. In this study, we collected analyzed from 70 sites across four bee-pollinated crops two years to characterize variation in detection sites, at different periods during bloom. Hazard Quotient, HQ, common way that are aggregated into a single hazard value current literature. Therefore, (HQ) was quantified composite samples traps color...
Cyclophilin D (CypD) is a key mitochondrial target for amyloid-β-induced and synaptic dysfunction considered potential drug Alzheimer's disease. The high-resolution crystal structures of primitive orthorhombic (CypD-o) tetragonal (CypD-t) forms have been determined to 1.45 0.85 Å resolution, respectively, are nearly identical structurally. Although an isomorphous structure CypD-t has previously reported, the reported here was at atomic while CypD-o represents new form this protein. In...
Researchers often collect and analyze corbicular pollen from honey bees to identify the plant sources on which they forage for or estimate pesticide exposure of via pollen. Described herein is an effective pollen-trapping method collecting returning their hives. This collection results in large quantities that can be used research purposes. Honey many species, but typically visit one species during each trip. Therefore, pellet predominantly represents described by color. allows sorting...