A5044381039- Fetal and Pediatric Neurological Disorders
- Tumors and Oncological Cases
- Teratomas and Epidermoid Cysts
- Glioma Diagnosis and Treatment
- Soft tissue tumor case studies
- Advanced MRI Techniques and Applications
- Neurofibromatosis and Schwannoma Cases
- Prenatal Screening and Diagnostics
- Medical Imaging Techniques and Applications
- Atomic and Subatomic Physics Research
- Bone Tumor Diagnosis and Treatments
- Meningioma and schwannoma management
- Congenital Heart Disease Studies
- Sleep and Wakefulness Research
- Neuroscience of respiration and sleep
- Vascular Malformations Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Spinal Dysraphism and Malformations
- Head and Neck Anomalies
- Ocular Disorders and Treatments
- Vascular Malformations and Hemangiomas
- Ocular Oncology and Treatments
- Coronary Artery Anomalies
- Congenital heart defects research
- Congenital Diaphragmatic Hernia Studies
Children's Hospital of Philadelphia
2011-2022
University of Pennsylvania
2007-2022
John Wiley & Sons (United Kingdom)
2020
Hudson Institute
2020
Philadelphia University
2011-2018
<h3>Background/aims</h3> Optic nerve tortuosity and sheath thickening are observed on MRI in some patients with neurofibromatosis type 1 (NF-1). This study aimed to determine if associated the development of optic pathway glioma (OPG) subsequent vision loss. <h3>Methods</h3> Children NF-1 who underwent brain between 1992 2005, had at least year visual acuity (VA) follow-up, were identified retrospectively. The baseline was independently reviewed by three neuroradiologists for consensus...
<h3>SUMMARY:</h3> Fluid-fluid levels can occur whenever different fluid densities are contained within a cystic or compartmentalized lesion, usually related to the evolution of hematoma necrosis. Review literature demonstrated that throughout skeletal system, most common etiology for fluid-fluid is aneurysmal bone cyst, but there no dedicated studies pediatric calvaria, our knowledge. In this report, we present clinicopathologic characteristics and CT MR imaging 11 patients with skull mass...
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder in which benign hamartomas develop multiple organ systems. Increasingly, stigmata of the disease, such as cardiac rhabdomyomas, are detected on routine prenatal ultrasound. Such a finding should prompt additional imaging studies order to confirm diagnosis and identify potential complications, vary greatly from patient patient. Early allows for accurate parental counseling, coordination high-level perinatal care, subspecialty...
Our goal is to correlate the findings on flexion and extension radiographs with dynamic magnetic resonance imaging (MRI), clinical history, in a nonrandomly selected cohort of patients 22q11.2 deletion syndrome (22q).All 22q who had MRI from January 2004 March 2015 were included. We analyzed multiple radiographic measurements both plain films MRIs, correlated these review each patient's medical record.Multiple congenital anomalies identified as noted previous studies, 61% failure fusion...
Infantile hemangiomas are common lesions in the pediatric population; rare cases, an infantile hemangioma can be detected along neural axis. The purposes of our study included determination incidence, location, and imaging appearance neuroaxial their syndromic association. We also assessed additional features cerebral cardiovascular anomalies that may associated with lesions.A retrospective cohort was performed, searching radiology database for patients segmental referred assessment possible...
Retinoblastoma (RB) is a malignant tumor of the retina and most common intraocular pediatric tumor. It typically affects children younger than 4 years age. Loss or mutation RB genes causes absence control protein subsequent uncontrolled cell division growth. In this review article, we describe how two forms RB—germline (40%) somatic sporadic (60%)—differ in their clinical presentation prognosis. The accurate diagnosis, staging, monitoring disease may be achieved with combination...
Abnormalities of the fetal orbit are occasionally visualized in workup suspected central nervous system malformation. It may be difficult to recognize orbital pathology fetuses, especially when it is bilateral and symmetric. In this article, we at first addressed a normal appearance orbits on prenatal imaging, which includes obstetric ultrasound magnetic resonance imaging. We also described spectrum lesions involving eyes orbits, including abnormal biometry, morphology vitreous lens,...
This review paper is dedicated to imaging of malignant orbital lesions in children. We reviewed pediatric primary and metastatic disease from a known distant malignancy. The features clinical presentation extraocular masses are often nonspecific overlap with each other benign lesions. emphasized common uncommon characteristics described the advantages shortcomings available modalities.
Two unrelated female infants presented at 9 days and 2 months, respectively, with apneic episodes in the former gaze preference latter. MRI revealed enlargement of almost entire right hemisphere, apparently smooth cortex, simplification gyral pattern, expanded white matter abnormal signal intensity containing multiple intraparenchymal cysts. Histologic examination both cases infiltration by a hypocellular lesion composed uniform, fibrillary astrocytes microcystic background. Multilocular...
OBJECTIVE: To determine if chemotherapy improves proptosis in patients with NF1/OPG.