- COVID-19 Clinical Research Studies
- Inflammasome and immune disorders
- Long-Term Effects of COVID-19
- Atherosclerosis and Cardiovascular Diseases
- Immunotherapy and Immune Responses
- Sepsis Diagnosis and Treatment
- MicroRNA in disease regulation
- Systemic Lupus Erythematosus Research
- Cancer Immunotherapy and Biomarkers
- SARS-CoV-2 and COVID-19 Research
- T-cell and B-cell Immunology
- Immune responses and vaccinations
- Plant chemical constituents analysis
- Viral Infections and Outbreaks Research
- Vector-borne infectious diseases
- Brain Metastases and Treatment
- Chemokine receptors and signaling
- Circular RNAs in diseases
- Antibiotic Resistance in Bacteria
- Peroxisome Proliferator-Activated Receptors
- Rheumatoid Arthritis Research and Therapies
- Trauma and Emergency Care Studies
- Lung Cancer Treatments and Mutations
- Zoonotic diseases and public health
- Extracellular vesicles in disease
Isfahan University of Medical Sciences
2021-2025
Hamedan University of Medical Sciences
2022
Shiraz University of Medical Sciences
2019-2021
Kerman University of Medical Sciences
2014
Abstract Long Covid-19 syndrome (LCS) manifests with a wide range of clinical symptoms, yet the factors associated LCS remain poorly understood. The current study aimed to investigate relationships that demographic characteristics, history, laboratory indicators, and frequency HLA-I alleles have likelihood developing LCS. We extracted characteristics histories from medical records 88 cases (LCS + group) 96 individuals without − group). Furthermore, we evaluated serum levels interleukin...
Adenosine triphosphate (ATP)-binding-cassette-transporter-A1 (ABCA1) transports cholesterol from cells into apolipoprotein A1 to form high-density lipoprotein (HDL) cholesterol.We investigated the frequencies of ABCA1 functional variants in 273 patients with coronary artery disease (CAD) and 261 age-matched, healthy blood donors southwest Iran. Sequence-specific primer polymerase-chain reaction (SSP-PCR) polymerase chain reaction-restriction fragment-length polymorphism (PCR-RFLP) were used...
Background: Detection of various environmental allergens is the major challenge in allergic diseases and only treatment avoiding these allergens. The aim this study was to determine prevalence food airborne patients using Skin Prick Test (SPT). Methods: A cross-sectional done on clinically confirmed atopic-dermatitis (n=54), allergenic-rhinitis (n=64) chronic-urticaria (n=39) who referred asthma allergy clinic at Afzali-Pour hospital Kerman during 2008-2010. prick test allergen extracts...
Objective: Brain tumors are of high mortality and morbidity for which there is still no cure. The TNF family cytokine, A Proliferation Inducing Ligand (APRIL), shown to help proliferation development tumor cells. We assessed serum levels APRIL in patients with glioma, meningioma schwannoma comparison healthy individuals. Methods: Peripheral blood samples 68 brain tumors, divided into three groups gliomas (n=25), meningiomas (n=30) schwannomas (n=13), as well 45 individuals were obtained....
known to be highly resistant current antibiotics due both intrinsic and acquired resistance mechanisms within the bacteria. Objectives: This study aimed detect determine drug patterns in different P. aeruginosa strains isolated from clinical specimens hospitals of Isfahan, Iran. Materials Methods: In this descriptive cross-sectional study, approximately 255 bacterial isolates were gathered samples blood, sputum, urine, wounds, burns, respiratory systems, catheter, eye peritoneum major Iran,...
HLA molecules are inherited key in the immune inflammation and specific responses to environmental pathogens. We investigated association of HLA-A alleles with Varicella zoster virus (VZV) seropositivity patients atherosclerosis (AS).Plasma Anti-VZV IgG molecular type were detected 203 (100 AS+ 103 AS-) individuals.Of 100 individuals, 66 anti-VZV+ 34 anti-VZV-. Of age/sex-matched AS- 59 44 Anti-VZV-IgG cases was higher than controls (p = .034). The mean anti-VZV HLA-A*02+AS+ individuals...
The relationship between high levels of anti-Varicella Zoster Virus (VZV) IgG in cerebrospinal fluid (CSF) and cerebrovascular atherosclerosis commends a possible similar association other vessels. We aimed to investigate the VZV-seropositivity with coronary artery atherosclerosis. recruited 88 newly diagnosed patients more than 50% stenosis at least one main arteries. As control group, 99 age-matched individuals normal/insignificant findings were included. Clinical, paraclinical,...
Programmed death 1 (PD-1) has a central role in maintaining T cell tolerance and terminating cellular responses after eliminating antigens. Variation
Malaria parasites have gradually developed resistance to commonly used antimalarial drugs. For decades, chloroquine was the most widely drug eradicate malaria. However, with spread of resistance, many countries adopted combination therapies that utilize two drugs acting synergistically instead monotherapy. In this study, synergistic effect and semipolar extract Artemisia kopetdaghensis. Semipolar (SPE) investigated in vivo through pathological parasitological studies on mouse model. Sixty...
The elevated neutrophil-to-lymphocyte ratio (NLR) is associated with poor clinical outcomes, especially in pro-inflammatory states such as surgical injuries and severe hemorrhages. Therefore, it was hypothesized whether NLR value at the time of admission could be a prognostic indicator hospital mortality trauma patients. This retrospective cohort study conducted on 865 patients referred to Rajaee Hospital between April 2016 July 2019. calculated admission, receiver operating characteristics...
Background: Diabetes increases the risk of myocardial infarction (MI) by 2 to 3 folds. Tlymphocytes play a role in atherosclerosis, which is main pathology behind MI. Cellular immune responses beta-2 glycoprotein I (β2GPI) are shown carotid atherosclerosis. Objective: To investigate self-reactive, β2GPI-specific T-lymphocytes patients with and without diabetes Methods: Collectively, 164 subjects that underwent coronary angiography were divided into four groups based on their status stenosis....