A5044984947- Zebrafish Biomedical Research Applications
- Fish Ecology and Management Studies
- Human Pose and Action Recognition
- Advanced Vision and Imaging
- Molecular Sensors and Ion Detection
- Advanced Fluorescence Microscopy Techniques
- Biosensors and Analytical Detection
- Free Radicals and Antioxidants
- Eicosanoids and Hypertension Pharmacology
- Advanced biosensing and bioanalysis techniques
- Biomimetic flight and propulsion mechanisms
- Viral Infectious Diseases and Gene Expression in Insects
- Cell Image Analysis Techniques
- Nitric Oxide and Endothelin Effects
University of Illinois Urbana-Champaign
2018-2023
Renmin University of China
2014
Spatial and temporal distributions of metal ions in vitro vivo are crucial our understanding the roles biological systems, yet there is a very limited number methods to probe with high space time resolution, especially vivo. To overcome this limitation, we report Zn2+-specific near-infrared (NIR) DNAzyme nanoprobe for real-time ion tracking spatiotemporal control early embryos larvae zebrafish. By conjugating photocaged DNAzymes onto lanthanide-doped upconversion nanoparticles (UCNPs), have...
Abstract As an integral part of modern cell biology, fluorescence microscopy enables quantification the stability and dynamics fluorescence-labeled biomolecules inside cultured cells. However, obtaining time-resolved data from individual cells within a live vertebrate organism remains challenging. Here we demonstrate customized pipeline that integrates meganuclease-mediated mosaic transformation with fluorescence-detected temperature-jump to probe endogenously expressed proteins in different...
Quantitative ethology requires an accurate estimation of organism's postural dynamics in three dimensions plus time. Technological progress over the last decade has made animal pose challenging scenarios possible with unprecedented detail. Here, we present (i) a fast automated method to record and track individual larval zebrafish 3-D environment, applicable when human labeling is not possible; (ii) rich annotated dataset poses for ethologists general machine learning community; (iii)...
The efficient bleaching following continuous bubbling of gaseous nitric oxide (NO•) to β-carotene (β-Car) dissolved in n-hexane under anaerobic conditions results from an initial addition two NO• followed by fragmentation coupled with further as shown mass spectrometry (MS). Density functional theory (DFT) calculations demonstrated that hydrogen atom transfer (HAT) and electron (ET) β-Car are strongly energetically unfavorable contrast radical adduct formation (RAF) degradation. indicated...
Abstract Quantitative ethology requires an accurate estimation of organism’s postural dynamics in three dimensions plus time. Technological progress over the last decade has made animal pose challenging scenarios possible with unprecedented detail. Here, we present (i) a fast automated method to record and track individual larval zebrafish 3-D environment, applicable when human labeling is not possible; (ii) rich annotated dataset poses for ethologists general machine learning community;...