A5090399648- Electron Spin Resonance Studies
- Magnetism in coordination complexes
- Lanthanide and Transition Metal Complexes
- Hemoglobin structure and function
- Metal-Catalyzed Oxygenation Mechanisms
- Photosynthetic Processes and Mechanisms
- TiO2 Photocatalysis and Solar Cells
- Advanced Photocatalysis Techniques
- Protein Structure and Dynamics
- Metal complexes synthesis and properties
- Photonic and Optical Devices
- Acoustic Wave Resonator Technologies
- Iron oxide chemistry and applications
- Porphyrin Metabolism and Disorders
- Advancements in Battery Materials
- Characterization and Applications of Magnetic Nanoparticles
- Metalloenzymes and iron-sulfur proteins
- Microwave and Dielectric Measurement Techniques
- Advanced NMR Techniques and Applications
- Chromium effects and bioremediation
- Electrochemical Analysis and Applications
- Nanoparticle-Based Drug Delivery
- Luminescence Properties of Advanced Materials
- Multiferroics and related materials
- Amino Acid Enzymes and Metabolism
University of Florence
2014-2024
National Interuniversity Consortium of Materials Science and Technology
2011-2022
Istituto Nazionale di Fisica Nucleare, Sezione di Firenze
2009-2022
University of Miami
2014
Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati
2010
University of Padua
2010
University of Antwerp
2005-2009
ETH Zurich
2008
Chemnitz University of Technology
2008
Huygens Institute for History and Culture of the Netherlands
2003-2006
Magnetic nanoparticles, MNPs, mineralized within a human ferritin protein cage, HFt, can represent an appealing platform to realize smart therapeutic agents for cancer treatment by drug delivery and magnetic fluid hyperthermia, MFH. However, the constraint imposed inner diameter of shell (ca. 8 nm) prevents its use as heat mediator in MFH when MNPs comprise pure iron oxide. In this contribution, we demonstrate how limitation be overcome through controlled doping core with small amount...
Human serum albumin (HSA), the most prominent protein in blood plasma, is able to bind a wide range of endogenous and exogenous compounds. Among ligands, HSA significant transporter heme, heme−HSA complex being present plasma. Drug binding affects allosterically heme affinity for vice versa. Heme−HSA, their complexes with ibuprofen have been characterized by electronic absorption, resonance Raman, electron paramagnetic (EPR) spectroscopy. Comparison results systems has provided insight into...
Doping of biocompatible nanomaterials with magnetic phases is currently one the most promising strategies for development advanced biomaterials. However, especially in case iron-doped hydroxyapatites, it not clear if features come merely from phases/ions used as dopants or complex mechanisms involving interactions at nanoscale. Here, we report an extensive chemical-physical and investigation three hydroxyapatite nanocrystals doped different iron species containing small no amounts maghemite...
The current status and future developments of the use electron magnetic resonance (EMR) for investigation nano-systems is here reviewed. aim to stimulate efforts provide a unified view properties nanoparticles (MNP) comprising few hundred centres, molecular nanomagnets which contain up ca. one centres (MNM). size systems becoming same but approaches interpretation their are still different, being bottom latter top down former. We make point need common viewpoint, highlighting two fields...
The use of single molecule magnets (SMMs) as cornerstone elements in spintronics and quantum computing applications demands that magnetic bistability is retained when molecules are interfaced with solid conducting surfaces. Here, we employ synchrotron Mössbauer spectroscopy to investigate a monolayer tetrairon(III) (Fe4) SMM chemically grafted on gold substrate. At low temperature zero field, observe the pattern Fe4 molecule, indicating slow spin fluctuations compared timescale. Significant...
Abstract Boron‐doped anatase TiO 2 particles were effectively coupled with carbon nitride (CN) forming nanocomposites. The materials fully characterized by DR‐UV‐Vis, N adsorption‐desorption isotherms, XRD, Raman, FTIR, TGA, XPS, TEM, electron energy loss spectroscopy, photoluminescence, and paramagnetic spectroscopy (EPR) spectroscopy. developed heterojunctions applied as photocatalysts for hydrogen (H ) evolution the photoreforming process of ethanol under solar irradiation, using minimal...
Doping for the environment: Electron paramagnetic resonance and X-ray photoelectron spectroscopy investigations prove—for first time—that proximity of surface F surface/second layer B generates hole-trapping species responsible a remarkable photocatalytic activity rutile TiO2, even low-surface-area materials. A careful synthetic design doped TiO2 containing high concentration these may lead to significantly enhanced performances in pollutant degradation.
A cobalt(II)-based spin triangle shows a significant spin-electric coupling. [Co
Human α-Synuclein (aS), a 140 amino acid protein, is the main constituent of Lewy bodies, cytoplasmatic deposits found in brains Parkinson's disease patients, where it present an aggregated, fibrillar form. Recent studies have shown that aS metal binding protein. Moreover, heavy ions, particular divalent copper, accelerate aggregation process In this work, we investigated high affinity mode truncated (1-99) (aS99) with Cu(II), stoichiometric ratio, to elucidate residues involved site and...
The interaction between cytochrome c (Cyt c) and cardiolipin (CL) plays a vital role in the early stages of apoptosis. binding CL to Cyt induces considerable increase its peroxidase activity that has been attributed partial unfolding protein, dissociation Met80 axial ligand, formation non-native conformers. Although extensively studied, there is still no consensus regarding conformational rearrangements follow protein–lipid interaction. To rationalize different results gain better insight...
Measurements for the determination of complex permittivity liquid and solid materials based on use whispering gallery (WG) dielectric resonators are presented. The procedure implies measurement electromagnetic parameters involved resonator interacting with material under study. field distribution in different WG resonant modes was obtained by an analytical calculation mode matching method approximation. results this calculation, combined experimental data, well account values interest. Due...
In spite of the tremendous progress in field pulse electron paramagnetic resonance (EPR) recent years, these techniques have been scarcely used to investigate high-spin (HS) ferric heme proteins. Several technical and spin-system-specific reasons can be identified for this. Additional problems arise when no single crystals protein are available. this work, we use example a frozen solution aquometmyoglobin (metMb) show how multi-frequency EPR approach overcome problems. particular,...
Abstract A comparative analysis of the magnetic properties iron oxide nanoparticles grown in cavity D NA‐binding p rotein from s tarved cells bacterium Listeria innocua , LiDps and its triple‐mutant lacking catalytic ferroxidase centre, LiDps‐tm is presented. TEM images static dynamic electron resonance (EMR) measurements reveal that, under applied preparation conditions, namely alkaline pH, high temperature (65 °C), exclusion oxygen, presence hydrogen peroxide, maghemite and/or magnetite...
In an effort to build a unitary view of the properties magnetic nanoparticles (MNPs) and molecular nanomagnets (MNMs), we investigated with different techniques MNPs spinel-type iron oxide approximately 3.5 8 nm mineralized in internal cavity ferritin-type proteins. particular, used electron resonance (EMR) static dynamic measurements took advantage capacity protein shells control size MNPs. A signal at half-field EMR spectrum is observed for as big cavities. This feature has been...
Variants of the copper-containing nitrite reductase (NiR) Alcaligenes faecalis S6 were constructed by site-directed mutagenesis, which C-terminal histidine ligand (His145) Cu in type-1 site was replaced an alanine or a glycine.The sites NiR variants as isolated, are reduced form, but can be oxidized presence external ligands, like (substituted) imidazoles and chloride.The reduction potential NiR-H145A reconstituted with imidazole amounts to 505 mV vs NHE (20 °C, pH 7, 10 mM imidazole), while...
A multifrequency electron paramagnetic resonance, EPR, study has been carried out on TiO2 nanocrystals (NCs) capped by organic moieties prepared according to both a nonhydrolytic and hydrolytic procedure, respectively, with spherical or rodlike shape. In particular, EPR measurements have performed in the 9−95 GHz range, at various temperatures, without UV irradiation. The behavior of electrons promoted conduction band irradiation holes valence monitored means generated species that are...