- Antifungal resistance and susceptibility
- COVID-19 Clinical Research Studies
- HIV-related health complications and treatments
- Antibiotic Use and Resistance
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Antimicrobial Resistance in Staphylococcus
- Neutropenia and Cancer Infections
- HIV/AIDS drug development and treatment
- Nail Diseases and Treatments
- Maternal and Neonatal Healthcare
- Diabetes and associated disorders
- Health and Medical Education
- Pneumocystis jirovecii pneumonia detection and treatment
- Antibiotic Resistance in Bacteria
- Infectious Diseases and Mycology
- Prenatal Screening and Diagnostics
- Parasites and Host Interactions
- Plant Pathogens and Fungal Diseases
- Streptococcal Infections and Treatments
- Nosocomial Infections in ICU
- Ethics and bioethics in healthcare
- HIV Research and Treatment
- Bacterial Identification and Susceptibility Testing
- Fungal Infections and Studies
- Cytomegalovirus and herpesvirus research
Fundación Santa Fe de Bogotá
2008-2024
Fundación Universitaria Sanitas
2020-2024
Universidad del Rosario
2019-2022
Asociación Colombiana de Infectología
2020-2021
Clínica Santa María
2020
Hospital Clínico Universitario de Caracas
2007-2011
Universidad Nacional de Colombia
2010
Instituto de Salud Carlos III
2008
Cancer Research UK
2008
Universidad El Bosque
2008
A. Vera, F. Contreras, Guevara. Incidence and risk factors for infections after liver transplant: single‐center experience at the University Hospital Fundación Santa Fe de Bogotá, Colombia. Transpl Infect Dis 2011: 13: 608–615. All rights reserved Abstract: The incidence of in transplant patients is higher compared with recipients other organs, are one major complications transplantation. aim our study was to evaluate incidence, presentation a Latin‐American population, compare results data...
Patients with cancer have a higher risk of severe bacterial infections. This study aims to determine the frequency, susceptibility profiles, and resistance genes species involved in bacteremia, as well factors associated mortality patients Colombia. In this prospective multicenter cohort adult testing was performed selected were identified. A multivariate regression analysis carried out for identification mortality. 195 patients, 206 microorganisms isolated. Gram-negative bacteria more...
Abstract Background Cefazolin is an alternative for the treatment of MSSA infections and first choice option surgical prophylaxis. The cefazolin inoculum effect (CzIE), increase in MIC at high bacterial inocula associated to therapeutic failures increased mortality deep-seated infections. prevalence CzIE among nasal colonizing from ICU patients currently unknown. aim this study was investigate recovered admitted ICUs Colombia. Methods We evaluated 33 isolates swabs 29 6 high-complexity...
Las infecciones de piel y tejidos blandos (IPTB) representan la tercera causa consulta por enfermedad infecciosas a los servicios médicos, después las respiratorias urinarias. Se presenta una guía práctica clínica (GPC) con 38 recomendaciones basadas en evidencia, graduadas bajo el sistema SIGN, para diagnóstico tratamiento pacientes adultos IPTB contexto colombiano, posterior un proceso adaptación GPC publicadas búsqueda sistemática síntesis literatura actualización evidencia científica....
La pandemia por el virus SARS-CoV-2 y la enfermedad generada (COVID-19, del inglés Coronavirus 2019 Disease), llevó a nivel mundial cambios significativos en forma de prestar los servicios salud, incluida actividad quirúrgica. Como parte esta realidad, se recomendó Colombia adopción disposiciones enfocadas preparar nuestro sistema salud para enfrentar una avalancha pacientes COVID-19, que esperaba fuera similar presentada otros países. Las medidas tomaron momento oportuno, ganando tiempo...
ABSTRACT The cefazolin inoculum effect (CzIE) has been associated with poor clinical outcomes in patients methicillin-susceptible Staphylococcus aureus (MSSA) infections. We aimed to investigate the point prevalence of CzIE among nasal colonizing MSSA isolates from ICU a multicenter study Colombia (2019–2023). Patients underwent swabs assess for S. colonization on admission ICU, and some individuals had follow-up swabs. performed MIC by broth microdilution using standard high developed...
La infección de vías urinarias complicada es la que ocurre en alguna las estructuras del tracto urinario, pacientes con comorbilidad, o anomalías estructurales funcionales urinario. tiene un alto impacto morbilidad, mortalidad y problemática actual resistencia a los antimicrobianos, por lo resulta importancia generar directrices permitan orientar el adecuado diagnóstico tratamiento este grupo pacientes, objetivo obtener mejores desenlaces clínicos propender uso racional antibióticos....
El citomegalovirus es una de las principales causas infección y enfermedad en receptores trasplante renal, con un notorio impacto términos morbilidad, mortalidad costos. Sin embargo, no existe Colombia práctica clínica estandarizada entre los centros trasplante, por lo cual, suma importancia disponer guías el fin orientar la estratificación, diagnóstico laboratorio, tratamiento prevención pacientes adultos renal. A través metodología ADAPTE para evaluación calidad transculturización a...
Intra-abdominal infections are frequent at all levels of health care, therefore, it is necessary to maintain a high level clinical suspicion, performing the fastest and most cost-effective measures confirm diagnosis offer precise targeted multidisciplinary therapy, this being only way have an impact on morbidity infection, reducing mortality minimizing complications costs care. linked appearance selection resistant mutants in both bacteria fungi, becoming currently major public problem....
El género Aspergillus es ubicuo en la naturaleza y de distribución universal. Por esta razón, el contacto con este hongo incluye hospederos inmunocompetentes e inmunosuprimidos. La vía aérea forma más frecuente adquirir sus manifestaciones clínicas localización topográfica se relacionan interacción del capacidad inmunológica hospedero. principal manifestación clínica a nivel respiratorio, un impacto muy importante mortalidad morbilidad, especialmente paciente inmunosuprimido. Los pacientes...
For a long time, the diagnostic approach to IA/Aspergillus disease has been challenge. The definitive diagnosis is made by correct microbiological and/or histopathological documentation, undoubtedly fundamental cornerstone for therapeutic decision-making. However, it considered limited lack of sensitivity and speed, often being counterproductive, as in many cases invasive procedures are needed (e.g., fibrobronchoscopy [FBC] or tissue biopsy), which delays treatment undermines survival...
La estrongiloidiasis es una enfermedad causada por el nematodo Strongyloides stercoralis, endémico en las regiones rurales de los países tropicales y subtropicales. Los pacientes inmunosuprimidos tienen un mayor riesgo infección con este parásito pueden terminar desarrollando síndrome hiperinfección que conlleva alto muerte. En tratamiento se utiliza la ivermectina, pero, ni Colombia mundo, existe presentación parenteral del medicamento para uso humanos, lo cual problema aquellos puedan...
The cefazolin inoculum effect (CzIE) has been associated with poor clinical outcomes in patients MSSA infections. We aimed to investigate the point prevalence of CzIE among nasal colonizing isolates from ICU a multicenter study Colombia (2019-2023). Patients underwent swabs assess for
Carbapenemase-producing Enterobacterales (CPE) infections have increased in recent years. Colombia has become an endemic country for this group of microorganisms, and the they cause a serious impact terms morbidity mortality. The early identification CPE carriers who are admitted to health care centers as patients is necessary implement adequate isolation infection control measures limit spread type microorganisms hospitals. Furthermore, treating these challenging task due limited...
La neumonía sigue siendo una de las principales causas consulta y hospitalización a la que, además su un alto impacto en términos morbilidad mortalidad, se suma actual problemática resistencia los antimicrobianos, por lo que establecer directrices permitan adecuado diagnóstico tratamiento es gran importancia para obtener mejores desenlaces clínicos promover uso racional antibióticos estos pacientes. presente guía práctica clínica (GPC) contiene recomendaciones basadas evidencia el adquirida...
The invasive aspergillosis (IA) continues to be an important cause of morbidity and mortality, difficult manage in severely immunocompromised patients, however, with its appearance a heterogeneous group patients (e.g., critical ICU human immunodeficiency virus [HIV/AIDS], etc.), who were not classically considered high risk, as well more chronic forms aspergillosis, (including those propensity for invasion), which have been better defined, different antifungal treatment modalities...
La unidad de perinatología del Hospital Universitario Caracas, fue fundada en 1975 por los doctores Freddy Guevara y Miguel Yáber; su objetivo ha sido mejorar la salud materno-fetal para solución principales problemas perinatales.Dentro sus objetivos específicos, está formación subespecialistas perinatología; residencia inicia enero 1989, bajo dirección doctor Guevara.Actualmente cuenta con una moderna planta física el tecnología punta, convenios interinstitucionales un equipo profesionales...
Hemopoietic progenitor cells give rise to all cellular elements of the blood and are importance as a potential source used for correction various pathological conditions. The main objective this study was identify quantitative hemopoietic cell in antenatal fetal blood, cord at time delivery adult using monoclonal antibodies surface markers flow cytometry. CD34+ cells, most them probably representing were detected prenatal early 17th week gestation. proportion these showed tendency decrease...
Purpose of the studyRaltegravir (RAL) is first marketed HIV integrase inhibitor.It has shown considerable potency and safety in clinical trials conducted antiretroviral (ARV)-experienced HIV+ patients.This study aims to assess performance RAL a routine practice, as part therapeutic strategies besides salvage therapy. MethodsRetrospective longitudinal assessment all patients who received at our institution until June 2008.Overall, drug was prescribed regimen or with undetectable plasma...
Introduction: recent studies have reported the occurrence of thrombotic phenomena or coagulopathy in patients with COVID-19.There are divergent positions regarding prevention, diagnosis, and treatment these phenomena, current clinical practice is based solely on deductions by extension from retrospective studies, case series, observational international guidelines developed prior to pandemic.Objective: generate a group recommendations diagnosis management complications associated...