- Antibiotic Use and Resistance
- Antifungal resistance and susceptibility
- HIV/AIDS Research and Interventions
- Public Health and Environmental Issues
- HIV/AIDS oral health manifestations
- COVID-19 Clinical Research Studies
- Fungal Infections and Studies
- Bacterial Identification and Susceptibility Testing
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV, Drug Use, Sexual Risk
- Sepsis Diagnosis and Treatment
- Mosquito-borne diseases and control
- Antibiotic Resistance in Bacteria
- Drug-Induced Adverse Reactions
- Pneumonia and Respiratory Infections
- HIV-related health complications and treatments
- Nail Diseases and Treatments
- Immunodeficiency and Autoimmune Disorders
- Health and Medical Education
- Antimicrobial Resistance in Staphylococcus
- Cytomegalovirus and herpesvirus research
- Sinusitis and nasal conditions
- Toxoplasma gondii Research Studies
- Nosocomial Infections in ICU
- Malaria Research and Control
Universidad del Valle
2013-2025
Hospital Universitario del Valle ESE
2010-2023
Universidad Libre de Colombia
2021
Senko Medical Instrument Manufacturing (Japan)
2021
Pontificia Universidad Javeriana
2019-2020
Hospital General Universitario Morales Meseguer
2020
Fundación Universitaria Sanitas
2020
Fundación Valle del Lili
2019
Universidad del Valle
2018
Clínica Santa María
2017
Ivermectin is widely prescribed as a potential treatment for COVID-19 despite uncertainty about its clinical benefit.To determine whether ivermectin an efficacious mild COVID-19.Double-blind, randomized trial conducted at single site in Cali, Colombia. Potential study participants were identified by simple random sampling from the state's health department electronic database of patients with symptomatic, laboratory-confirmed during period. A total 476 adult disease and symptoms 7 days or...
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread throughout Latin America, a region swept multiple previous and ongoing epidemics. There are significant concerns that the arrival of COVID-19 is currently overlapping with other viruses, particularly dengue, in various endo-epidemic regions across South America. In this report, we analyzed trends for both viral infections Colombia during first 20 epidemiological...
Abstract Background Antimicrobial stewardship programs (ASPs) have become a fundamental pillar in optimizing antimicrobial usage, improving patient care, and reducing resistance (AMR). Herein we evaluated the impact of an ASP on consumption AMR Colombia. Methods We designed retrospective observational study measured trends antibiotic before after implementation using interrupted time series analysis over 4-year period (24 months 24 implementation). Results ASPs were implemented according to...
CTX-M-15-producing Escherichia coli has emerged worldwide as an important pathogen associated with community-onset infections, but in South America reports are scarce. We document the presence of E. international ST131 and ST405 clones Colombia present first molecular characterization these isolates America.
Abstract Background The monkeypox virus, part of the Orthopoxvirus genus, triggered a worldwide outbreak in 2022. While this had widespread effects, there's limited information on mpox's specific impact Colombia, particularly terms how it is managed, its burden, and epidemiology. This research seeks to examine medical context, clinical variations, health consequences individuals diagnosed with mpox, especially those HIV Colombian institutions Methods retrospective study was conducted...
ObjectivesMethicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections (SSTIs) represent a major clinical problem in Colombia. The aim of this study was to evaluate the risk factors associated with MRSA SSTI Colombia.MethodsA multicenter cohort nested case–control design performed. Patients an at least 48 h inpatient care were included. considered case group patients either non-MRSA or Methicillin-susceptible S. (MSSA) control groups. A multivariate logistic regression...
Introduction There is insufficient evidence supporting the use of rapid diagnostic tests (RDTs) for syphilis in people living with HIV (PLWH). We evaluated performance two commercially available RDTs (Bioline and Determine) PLWH Cali, Colombia. Methods A cross-sectional field validation study on consecutive adults confirmed diagnosis attending three outpatient clinics. Both were performed capillary blood (CB), obtained by finger prick, sera, venipuncture. combination treponemal enzyme linked...
Neumonía aguda
La resistencia bacteriana se consolida como una amenaza para los sistemas de salud en el manejo las enfermedades infecciosas. vigilancia epidemiológica la ha demostrado ser estrategia efectiva conocer patrones susceptibilidad a antimicrobianos regionales desarrollo medidas contención y gestión del uso adecuado antimicrobianos. Describir aislamientos microbiológicos perfiles principales bacterias gram-negativas gram-positivas clínicas hospitales alta complejidad Santiago Cali, Colombia....
Diabetes mellitus is an established risk factor for bacterial infections, but its role in cryptococcosis unclear. The study aimed to determine whether uncontrolled diabetes (HbA1c >7%) was independent mortality cryptococcosis.A retrospective case-control partially matched by age and gender performed patients tested Cryptococcus infection at the University of Colorado Hospital from 2000 2019. A multivariable logistic regression model used identify predictors. Cox proportional hazard survival...
In 2019, Colombia approved the combination of tenofovir disoproxil fumarate/emtricitabine for HIV Pre-Exposure Prophylaxis (PrEP). Therefore, we conducted a situational analysis in HIV-care providers to identify barriers and facilitators PrEP implementation. A survey was applied non-probabilistic sample health care workers HIV-specialized clinics. We examined awareness familiarity, comfort with PrEP-related activities, perceived implementation, concerns, attitudes. Poisson regressions...
Few studies have used implementation science frameworks to identify determinants of PrEP prescription by healthcare providers. In this work, we developed and psychometrically examined a questionnaire using the theoretical domains framework (TDF) consolidated for research (CFIR). We investigate what factors influence intention providers offer care advocate PrEP.We conducted cross-sectional study in 16 HIV organizations Colombia. A 98-item was administered online 129 professionals. One hundred...
Evaluar el impacto de un programa uso regulado antibióticos en observancia, consumo antibiótico y resistencia bacteriana 2 unidades cuidados intensivos (UCI) hospital universitario tercer nivel Colombia. Estudio prospectivo observacional intervención que analiza períodos tiempo UCI: preintervención (agosto 2008 a febrero 2009) posintervención (marzo septiembre 2009). El estudio se llevó cabo Hospital Universitario del Valle Evaristo García E.S.E. Se evaluaron: observancia guías creadas por...
Schizophyllum commune is a basidiomycete fungus with broad distribution in nature; however, it rare cause of infectious disease. We report the isolation this mould 46 year-old immunocompetent patient chronic sinusitis previously treated multiple antibiotics and topical nasal steroids. Material obtained via left maxillary sinus antrostomy showed septate hyaline hyphae clamp connections on direct examination KOH histopathological studies. Further growth Sabouraud agar produced white that,...
Abstract Background The HLA-B*57:01 allele is associated with a hypersensitivity reaction to abacavir. Due the lack of knowledge prevalence in Colombia, routine screening not performed and recommended by national guidelines. We aimed determine HIV population from Colombia. Methods This cross-sectional study included naïve HIV-infected adults 13 cities country. presence was determined using SSP-PCR blood samples. Prevalence rates were stratified sex, race, region origin. Results Colombian...
La criptococosis es la infección fúngica ocasionada por el complejo de especies Cryptococcus neoformans y gattii, desarrollada con mayor frecuencia en personas compromiso del sistema inmune. En las que viven virus inmunodeficiencia humana (VIH), una oportunista gran importancia, consecuencias devastadoras para los pacientes, sociedad salud, debido al incremento morbilidad, mortalidad costos genera. presente guía contiene recomendaciones diagnóstico tratamiento adultas VIH, basadas evidencia,...
BackgroundCarbapenemase-producing Enterobacterales (CPE) represents a significant threat to global health. This study aimed characterize clinically and molecularly the CPE isolated from rectal swabs of patients in intensive care units (ICUs) tertiary hospital Cali, Colombia.MethodsThis was cross-sectional observational study. Rectal admitted ICUs were collected. Bacterial identification carbapenemase production determined using phenotypic molecular methods. Demographic clinical data...