Alberto Paniz‐Mondolfi

ORCID: 0000-0003-1259-1736
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About
Contact & Profiles
Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Mosquito-borne diseases and control
  • Viral Infections and Vectors
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 detection and testing
  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Viral Infections and Outbreaks Research
  • COVID-19 epidemiological studies
  • Vector-borne infectious diseases
  • Long-Term Effects of COVID-19
  • Zoonotic diseases and public health
  • COVID-19 diagnosis using AI
  • Animal Virus Infections Studies
  • Virology and Viral Diseases
  • Bacillus and Francisella bacterial research
  • Rabies epidemiology and control
  • Respiratory viral infections research
  • Insect symbiosis and bacterial influences
  • Mycobacterium research and diagnosis
  • Poxvirus research and outbreaks
  • Herpesvirus Infections and Treatments
  • Biosensors and Analytical Detection
  • Leprosy Research and Treatment
  • Malaria Research and Control

Icahn School of Medicine at Mount Sinai
2020-2025

Mount Sinai Health System
2023-2025

Mount Sinai Hospital
2020-2024

Instituto de Estudios Avanzados
2012-2024

Mount Sinai Hospital
2024

Central University of Venezuela
2024

Universidad del Rosario
2024

Fundacion Venezolana de Investigaciones Sismologicas
2023

Incubadora Venezolana de la Ciencia
2020-2023

Instituto Venezolano de Investigaciones Científicas
2012-2023

Neurologic sequelae can be devastating complications of respiratory viral infections. We report the presence virus in neural and capillary endothelial cells frontal lobe tissue obtained at postmortem examination from a patient infected with severe acute syndrome coronavirus-2 (SARS-CoV-2). Our observations tissue, conjunction clinical correlates worsening neurologic symptoms, pave way to closer understanding pathogenic mechanisms underlying central nervous system involvement by SARS-CoV-2.

10.1002/jmv.25915 article EN Journal of Medical Virology 2020-04-21

The recent emergence of B.1.1.529, the Omicron variant

10.1038/s41586-022-04441-6 article EN cc-by Nature 2022-01-21

Leprosy, a chronic human disease with potentially debilitating neurological consequences, results from infection Mycobacterium leprae. This unculturable pathogen has undergone extensive reductive evolution, half of its genome now occupied by pseudogenes. Using comparative genomics, we demonstrated that all extant cases leprosy are attributable to single clone whose dissemination worldwide can be retraced analysis very rare single-nucleotide polymorphisms. The seems have originated in Eastern...

10.1126/science/1109759 article EN Science 2005-05-12

Blighted Gotham Deaths caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New York City (NYC) during the spring of 2020 have vastly exceeded those reported China and many other countries. What were early events that led to such a outbreak? Gonzalez-Reiche et al. sampled some patients seeking assistance February March at Mount Sinai Health System. Phylogenetic analysis virus sequences these people, who drawn from across NYC, showed had been independently introduced...

10.1126/science.abc1917 article EN cc-by Science 2020-05-29

In the southern region of United States, such as in Louisiana and Texas, there are autochthonous cases leprosy among native-born Americans with no history foreign exposure. same region, well Mexico, wild armadillos infected Mycobacterium leprae.

10.1056/nejmoa1010536 article EN New England Journal of Medicine 2011-04-27

BACKGROUND Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and its associated clinical syndrome COVID-19 are causing overwhelming morbidity mortality around the globe, disproportionately affecting New York City. A comprehensive, integrative autopsy series that advances mechanistic discussion surrounding this disease process is still lacking. METHODS Autopsies were performed at Mount Sinai Hospital on 67 positive patients data from records obtained Data Warehouse. The...

10.1101/2020.05.18.20099960 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-05-22

Abstract In December 2019, the a novel coronavirus disease (COVID‐19) caused by severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) first emerged in Wuhan, China. This has now spread worldwide and was declared pandemic March 2020. Initially, pediatric population described as low risk for COVID‐19. However, reports have recently of cases COVID‐19 children with systemic inflammatory disease, features that overlap Kawasaki (KD). We describe 15 multi‐systeminflammatory (MIS‐C),...

10.1002/jmv.26224 article EN Journal of Medical Virology 2020-06-25

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. The proportion of infected individuals who seroconvert is still an open question. In addition, it been shown in some that viral genome can be detected up to 3 months after symptom resolution. We investigated both seroconversion and PCR positivity large cohort convalescent serum donors the New York City (NY, USA) region.In this observational study, we ran outreach programme area. recruited participants...

10.1016/s2666-5247(20)30120-8 article EN cc-by-nc-nd The Lancet Microbe 2020-09-25

Abstract Persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have been reported in immune-compromised individuals and people undergoing immune-modulatory treatments. Although intrahost evolution has documented, direct evidence of subsequent transmission continued stepwise adaptation is lacking. Here we describe sequential persistent SARS-CoV-2 three that led to the emergence, forward transmission, a new Omicron sublineage, BA.1.23, over an eight-month period....

10.1038/s41467-023-38867-x article EN cc-by Nature Communications 2023-06-03

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread throughout Latin America, a region swept multiple previous and ongoing epidemics. There are significant concerns that the arrival of COVID-19 is currently overlapping with other viruses, particularly dengue, in various endo-epidemic regions across South America. In this report, we analyzed trends for both viral infections Colombia during first 20 epidemiological...

10.1002/jmv.26194 article EN Journal of Medical Virology 2020-06-19
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