Xiaotong Zhou

ORCID: 0000-0002-6457-9715
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About
Contact & Profiles
Research Areas
  • Minerals Flotation and Separation Techniques
  • Advanced biosensing and bioanalysis techniques
  • Metal Extraction and Bioleaching
  • Nanoplatforms for cancer theranostics
  • Geological and Geochemical Analysis
  • Mineral Processing and Grinding
  • Enzyme function and inhibition
  • Extraction and Separation Processes
  • Advanced Nanomaterials in Catalysis
  • Drug Transport and Resistance Mechanisms
  • Nanocluster Synthesis and Applications
  • Biosensors and Analytical Detection
  • Environmental Chemistry and Analysis
  • Geochemistry and Geologic Mapping
  • Pharmacogenetics and Drug Metabolism
  • Mass Spectrometry Techniques and Applications
  • TiO2 Photocatalysis and Solar Cells
  • Advanced Drug Delivery Systems
  • DNA and Nucleic Acid Chemistry
  • Synthesis and Catalytic Reactions
  • Molecular Sensors and Ion Detection
  • earthquake and tectonic studies
  • Insect-Plant Interactions and Control
  • Healthcare professionals’ stress and burnout
  • Advanced Photocatalysis Techniques

Hainan University
2025

Macau University of Science and Technology
2025

Shandong University of Science and Technology
2024

Xuzhou Medical College
2024

North China Electric Power University
2024

Nanjing University of Aeronautics and Astronautics
2024

Affiliated Hospital of Xuzhou Medical College
2024

Northeastern University
2024

Universidad del Noreste
2024

Shihezi University
2024

An ideal cancer treatment should not only destroy primary tumors but also improve the immunogenicity of tumor microenvironment to achieve a satisfactory anti-tumor immune effect. We designed carbonic anhydrase IX (CAIX)-anchored rhenium(I) photosensitizer, named CA-Re, that performs type-I and type-II photodynamic therapy (PDT) with high efficiency under hypoxia (nanomolar-level phototoxicity), evokes gasdermin D (GSDMD) mediated pyroptotic cell death effectively stimulate immunogenicity....

10.1002/anie.202115800 article EN Angewandte Chemie International Edition 2021-11-29

Functional plants possess the ability to attract natural enemies or repel pests, and they play an important role in ecological regulation. While most studies have focused on impacts of individual plant combinations with similar functions there is a scarcity research effects combining different functions, particularly case orchard pests. In this study, we combined (Cnidium monnieri (L.) Brassica napus L.) that predators (Ocimum basilicum L. Mentha haplocalyx Briq.) pests determine if these...

10.1016/j.biocontrol.2024.105512 article EN cc-by-nc-nd Biological Control 2024-04-17

Drug resistance is a major challenge in cancer therapeutics. Abundant evidence indicates that DNA repair systems are enhanced after repetitive chemotherapeutic treatments, rendering cancers cells drug-resistant. Flap endonuclease 1 (FEN1) plays critical roles replication and counteracting stress, which key mechanism for many drugs to kill cells. FEN1 was previously shown be upregulated response damaging agents. However, it unclear about the transcription factors regulate expression human...

10.1186/s12885-015-1043-1 article EN cc-by BMC Cancer 2015-02-12

Polyethylene glycols (PEGs) are synthetic polymers composed of repeating ethylene oxide subunits. They display excellent biocompatibility and widely used as pharmaceutical excipients. To fully understand the biological fate PEGs requires accurate sensitive analytical methods for their quantitation. Application conventional liquid chromatography-tandem mass spectrometry (LC-MS/MS) is difficult because have polydisperse molecular weights (MWs) tend to produce multicharged ions in-source...

10.1021/acs.analchem.6b04058 article EN Analytical Chemistry 2017-04-18

Abstract An ideal cancer treatment should not only destroy primary tumors but also improve the immunogenicity of tumor microenvironment to achieve a satisfactory anti‐tumor immune effect. We designed carbonic anhydrase IX (CAIX)‐anchored rhenium(I) photosensitizer, named CA‐Re , that performs type‐I and type‐II photodynamic therapy (PDT) with high efficiency under hypoxia (nanomolar‐level phototoxicity), evokes gasdermin D (GSDMD) mediated pyroptotic cell death effectively stimulate...

10.1002/ange.202115800 article EN Angewandte Chemie 2021-11-29

With the explosion of social media platforms, a substantial amount data is generated from information network. Tensor-based multi-modal clustering methods have been widely applied in various scenarios network by mining potential correlative relationships large-scale heterogeneous data. Nevertheless, accuracy and efficiency tensor-based are seriously restricted noise curse dimensionality. Therefore, this paper presents Tucker-based (TuMC) an improved TuMC (ITuMC) to enhance clustering. First,...

10.1109/tbdata.2024.3524830 article EN IEEE Transactions on Big Data 2025-01-01

This study examines how research and development (R&D) expenditures, temperature fluctuations, rainfall variability influenced wheat productivity in China, India, Pakistan from 1996 to 2018. Drawing on data FAOSTAT, the Economic Survey, World Development Indicators, we employ Pooled Mean Group (PMG) Autoregressive Distributed Lag (ARDL) models explore short- long-run dynamics. Our findings indicate that R&D investments do not exert a significant short-run effect but play pivotal role...

10.3390/rsee2020010 article EN Regional science and environmental economics 2025-04-28
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