A5034212574- Multiple Sclerosis Research Studies
- Systemic Sclerosis and Related Diseases
- Trigeminal Neuralgia and Treatments
- Inflammasome and immune disorders
- Retinal and Optic Conditions
- Sleep and Wakefulness Research
- Mechanical Circulatory Support Devices
- Restless Legs Syndrome Research
- Autoimmune and Inflammatory Disorders Research
- Sphingolipid Metabolism and Signaling
- Migraine and Headache Studies
- Peripheral Neuropathies and Disorders
- Respiratory Support and Mechanisms
- Nutrition and Health in Aging
- Parkinson's Disease Mechanisms and Treatments
- Neurosurgical Procedures and Complications
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Medicinal Plants and Bioactive Compounds
- Cerebrovascular and Carotid Artery Diseases
- interferon and immune responses
- Cardiac Arrest and Resuscitation
- Hereditary Neurological Disorders
- Cerebral Venous Sinus Thrombosis
- Retinal Development and Disorders
- Otitis Media and Relapsing Polychondritis
Ankara Bilkent City Hospital
2023-2025
Sağlık Bilimleri Üniversitesi
2020-2025
University of Health Science
2025
Memorial Ankara Hospital
2021-2024
City Hospital
2024
Bilkent University
2024
State Hospital
2024
Ankara Mevki Asker Hastanesi
2022
Ankara Numune Eğitim ve Araştırma Hastanesi
2009-2020
Anadolu University
2016
Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease characterized by inflammation of white matter in the central nervous system. It has been indicated that this causes increased levels proinflammatory cytokines. Therefore, we aimed to evaluate if there possible association between inflammatory markers and Expanded Disability Status Scale (EDSS) score patients with MS.We reviewed data 127 (91 women 36 men) who were retrospectively diagnosed as MS according revised Mc...
Multiple sclerosis (MS) is a chronic, demyelinating disorder of the central nervous system that widely accepted to result from complex interplay genetic and environmental factors. The involvement clusterin in neurodegenerative autoimmune diseases has been highlighted, but its role MS remains unclear. This study aimed investigate association four single nucleotide polymorphisms (SNPs) gene (CLU) with susceptibility. group consisted 310 patients RRMS (pwRRMS) controls. 25 treatment-naïve...
The role of atherosclerosis in ischemic stroke has been intensively investigated recent years, and homocysteine (Hcy) lipoprotein(a) Lp(a) were found to have roles during the process. This study aims investigate relationship between acute Hcy levels determine prognosis functional disability. Forty-one patients with 33 controls included study. examined both groups. modified Rankin scale (MRS) scores at discharge first third months determined establish disability patients. In stroke,...
Background. Nitric oxide synthase (NOS) is present in the brain and cerebral arteries it enables synthesis of nitric (NO), which plays a critical role perfusion. Asymmetrical dimethylarginine (ADMA) an endogenous NOS inhibitor.Objectives. The aim this study was to evaluate serum ADMA levels, are indicator endothelial dysfunction renal functions patients with acute ischemic stroke, determine whether there possible correlation between NO levels l-arginine-to-ADMA ratio.Material Methods....
By comparing neurocognitive test results from patients with obstructive sleep apnea syndrome (OSAS) and those simple snoring, we aimed to establish whether OSAS negatively influences cognition. Patients mild-to-severe (n = 29) nonhypoxic simple-snoring 30) were admitted the study. All participants in both groups evaluated polysomnography tests, including Stroop Test, Rey Auditory Verbal Learning Judgment of Line Orientation, Trail-Making Symbol Digit Modalities Test (SDMT). Significant...
Alterations in blink reflex excitability may occur the contralateral side (CLS) and symptomatic after peripheral facial palsy (PFP). In this study, alterations of CLS were evaluated cases with PFP who showed "three different types" recovery. For purpose, R2 response area recovery curve evaluated. The study included 51 patients suffering from 20 age- sex-matched healthy controls. Cases divided into three groups: partially cured accompanied by synkinesis (postfacial syndrome), residual...
Abstract Continuous‐flow left ventricular assist devices (LVADs) reduce peak systolic flow, increase diastolic and eliminate pulsatility of circulation. Altered blood flow may lead to a change in end‐organ perfusion. Analysis the dynamics arteries end organs, such as brain, indicate whether an organ is perfused sufficiently. The aim this study evaluate identify pattern changes carotid (CA) middle cerebral (MCA) LVAD patients compare with heart failure healthy volunteers. Eighty‐nine...
Abstract This study aimed to assess the possible association between cognitive impairment and two important biochemical biomarkers of oxidative stress, thiol‐disulfide homeostasis (TDH), ischemia‐modified albumin (IMA) in patients with multiple sclerosis (MS). included 85 MS (38 treatment‐naïve relapsing–remitting (RRMS), 31 RRMS on fingolimod therapy, 16 secondary progressive (SPMS)) 33 healthy controls. Cognitive evaluation was carried out by applying Brief International Assessment for...
Objective: Guillain-Barre syndrome (GBS) is an immune-mediated disorder of peripheral nerves resulting as acute inflammatory demyelinating polyradiculoneuropathy.GBS has a heterogeneous clinical course and laboratory findings.Acute onset progressive course, usually associated with good prognosis but some forms have poor prognosis.Factors that can affect the GBS been investigated in several studies.Assessment prognostic factors plays vital role management monitorization patients. Methods:In...
Multiple sclerosis (MS), a neuroinflammation that results in neurodegeneration, is the most prevalent central nervous system inflammatory disease young people. A diet rich antioxidants known to decrease production/activity of pro-inflammatory cytokines and have positive impact on prognosis MS. The purpose this study was assess if dietary antioxidant capacity related Expanded Disability Status Scale (EDSS) scores patients with Patients MS (n=220; 137 women 83 men) were asked complete...
<title>Abstract</title> <bold>Introduction</bold>: Osmophobia is an isolated phobia that especially common in patients with primary headaches. recommended for inclusion the migraine diagnostic criteria because it increases sensitivity and shows absolute specificity. Although there are publications supporting frequency of osmophobia tension-type headache (TTH), association between TTH has not been definitively demonstrated, various studies have conducted on this subject. This study aimed to...
Introduction Osmophobia is hypersensitivity to certain odors. Although osmophobia a symptom related migraine, it also reported in tension-type headache (TTH). recommended for inclusion the migraine diagnostic criteria because increases sensitivity and shows absolute specificity. However, there no evidence of association between TTH osmophobia. This study aimed evaluate prevalence clinical characteristics cohort patients. Methods For current analysis, patients who met among diagnosed with...
To investigate the potential effects of systemic fingolimod treatment on parameters anterior segment eye and tear film function tests in patients with multiple sclerosis (MS).
Objective: Multiple sclerosis (MS) is an inflammatory, autoimmune, demyelinating disease characterized by multifocal inflammation, progressive myelin loss and consequent axonal demyelination. Pathogenic mechanisms of MS are oligodendrocyte damage as a result leukocyte chemotaxis to central nervous system production inflammatory mediators, demyelination neuronal injury. CXCL12 (SDF-1 alpha) basic chemokine which chemoattractant for resting activated T cells. We aimed evaluate whether levels...