A5102987919- Cholangiocarcinoma and Gallbladder Cancer Studies
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Heat shock proteins research
- Macrophage Migration Inhibitory Factor
- Epigenetics and DNA Methylation
- Forensic Entomology and Diptera Studies
- Insect and Pesticide Research
- Cancer-related gene regulation
- Peptidase Inhibition and Analysis
- Cancer-related molecular mechanisms research
- Pneumonia and Respiratory Infections
- RNA modifications and cancer
- Diagnosis and treatment of tuberculosis
- Turtle Biology and Conservation
- Insect Pest Control Strategies
- Telomeres, Telomerase, and Senescence
- vaccines and immunoinformatics approaches
- Cardiovascular Effects of Exercise
- Autopsy Techniques and Outcomes
- Health Services Management and Policy
- Land Rights and Reforms
- Physiological and biochemical adaptations
- Genetics, Aging, and Longevity in Model Organisms
- Biochemical and Molecular Research
Tropical Forest Research Institute
2024
Indian Council of Forestry Research and Education
2024
Indira Gandhi Agricultural University
2024
Jiwaji University
2014-2023
Krea University
2022
IFMR Graduate School of Business
2022
Government Medical College
2020-2021
Indian Institute of Technology BHU
2010
The University of Tokyo
2008
Abstract Bile serves diverse functions from metabolism to transport. In addition acids and salts, bile is composed of proteins secreted or shed by the hepatobiliary system. Although there have been previous efforts catalog biliary proteins, an in‐depth analysis proteome has not yet reported. We carried out fractionation non‐cancerous samples using a multipronged approach (SDS‐PAGE, SCX OFFGEL) followed MS on LTQ‐Orbitrap Velos mass spectrometer high resolution at both MS/MS levels....
Promoter methylation in various tumor suppressor genes is reported to influence gallbladder carcinogenesis. Here, we aimed identify status cancer (GBC) by performing a comprehensive genome-wide DNA profiling. The of 485,577 CpG sites were investigated using Illumina's Infinium Human Methylation 450 BeadChip array 24 tissues (eight each tumor, adjacent non-tumor, and gallstone). About 33,443 differentially methylated (DMRs) obtained the whole human genome, which 24,188 (72 %) hypermethylated...
Poor prognosis in gallbladder cancer is due to late presentation of the disease, lack reliable biomarkers for early diagnosis and limited targeted therapies. Early diagnostic markers novel therapeutic targets can significantly improve clinical management cancer. Proteomic analysis four cell lines based on invasive property (non-invasive highly invasive) was carried out using isobaric tags relative absolute quantitation labeling-based quantitative proteomic approach. The expression macrophage...
Ofloxacin (OFX) and moxifloxacin (MOX) are the most promising second line drugs for tuberculosis treatment. Although primary mechanism of action OFX MOX is gyrase inhibition, other possible mechanisms cannot be ruled out. Being functional moiety cell, proteins act as targets developing drugs, diagnostics therapeutics. In this study we have investigated proteomic changes Mycobacterium isolates induced by applying comparative approaches based on two-dinensional gel electrophoresis (2DE) along...
The incidence of Gallbladder Cancer (GBC) is found to be increasing in the rural populations north-central India. Role multiple demographic factors, including poor socio-economic conditions, illiteracy and miserable primary healthcare services appear significant factors for this increase. Here, we aim assess present status GBC India evaluate role immunological markers its management.A total 1845 cases different diseases, GBC, from urban areas both, registered at CHRI, Gwalior during...
Genetic variations are considered important for athletic performance. In this regard, polymorphisms in angiotensin I-converting enzyme (ACE) and α-actinin-3 genes widely studied their association with elite athlete status. The ACE gene regulates circulatory homeostasis, the I variant of insertion/deletion (ACE I/D) polymorphism being associated endurance performance, while R allele R577X ACTN3 gene, crucial fast glycolytic muscle fibers, has been speed power performances. present study...