Jorge Diogène

ORCID: 0000-0002-6567-6891
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About
Contact & Profiles
Research Areas
  • Marine Toxins and Detection Methods
  • Nicotinic Acetylcholine Receptors Study
  • Marine and coastal ecosystems
  • Neuroscience of respiration and sleep
  • Protist diversity and phylogeny
  • Environmental Toxicology and Ecotoxicology
  • Marine Biology and Environmental Chemistry
  • Microbial Community Ecology and Physiology
  • Marine Biology and Ecology Research
  • Forensic Toxicology and Drug Analysis
  • Molecular Sensors and Ion Detection
  • Neuroscience and Neuropharmacology Research
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Animal Ecology and Behavior Studies
  • Marine Bivalve and Aquaculture Studies
  • Marine Ecology and Invasive Species
  • Electrochemical sensors and biosensors
  • Vibrio bacteria research studies
  • Analytical chemistry methods development
  • Identification and Quantification in Food
  • Biocrusts and Microbial Ecology
  • Ion channel regulation and function
  • Environmental Chemistry and Analysis
  • Marine and coastal plant biology
  • Isotope Analysis in Ecology

Institute of Agrifood Research and Technology
2016-2025

Government of Catalonia
2008-2010

Instituto de Investigaciones Agropecuarias
2010

Oceanography Society
2005

Alfred-Wegener-Institut Helmholtz-Zentrum für Polar- und Meeresforschung
2005

Dalhousie University
2005

Norwegian Institute of Marine Research
2005

Centro Oceanográfico de Vigo
1997-1999

Instituto Español de Oceanografía
1997-1999

Inserm
1993-1995

Severe food poisoning events after the consumption of sharks have been reported since 1940s; however, there has no clear understanding their cause. Herein, we report for first time presence ciguatoxins (CTXs) in sharks. The identification by mass spectrometry CTXs, including two new analogues, a bull shark (Carcharhinus leucas) that was consumed humans, causing and death 11 people Madagascar 2013 is described. Typical neurotoxic ciguatera symptoms were recorded patients, toxicological assays...

10.1038/s41598-017-08682-8 article EN cc-by Scientific Reports 2017-08-09

Cyclic imines are lipophilic marine toxins that bioaccumulate in seafood. Their structure comprises a cyclic-imino moiety, responsible for acute neurotoxicity mice. have not been linked yet to human poisonings and regulated Europe, although the European Food Safety Authority requires more data perform conclusive risk assessment consumers. This work presents first detection of pinnatoxin G (PnTX-G) Spain 13-desmethyl spirolide C (SPX-1) shellfish from Catalonia (Spain, NW Mediterranean Sea)....

10.3390/md12063706 article EN cc-by Marine Drugs 2014-06-23

Tetrodotoxin (TTX) is a potent marine neurotoxin involved in poisoning cases, especially through the consumption of puffer fish. Knowledge toxicity equivalency factors (TEFs) TTX analogues crucial monitoring programs to estimate samples analyzed with instrumental analysis methods. In this work, were isolated from liver Lagocephalus sceleratus individual caught on South Crete coasts. A cell-based assay (CBA) for TTXs was optimized and applied establishment TEFs 5,11-dideoxyTTX,...

10.3390/md21080432 article EN cc-by Marine Drugs 2023-07-29

Cyst studies carried out in 2002–2003 on Mediterranean Sea sediment from seven different sites along the Catalan and Balearic coasts (Western Mediterranean) revealed a higher diversity of Alexandrium species region than was previously known. The cysts eight toxigenic, marine dinoflagellate genus are described, some, such as A. kutnerae, margalefi, peruvianum pseudogoniaulax, reported area for first time. This is also record resting taylori sediment, description known to date kutnerae...

10.1080/09670260600810360 article EN European Journal of Phycology 2006-08-01

The ouabain/veratridine-dependent neuroblastoma (neuro-2a) cell-based assay (CBA) was applied for the determination of presence ciguatoxin (CTX)-like compounds in ciguatera-suspected fish samples caught Canary Islands. In order to avoid matrix interferences maximal concentration wet weight tissue exposed neuro-2a cells set at 20 mg equivalent (TE) ml−1 according sample preparation procedure applied. present study, limit quantification (LOQ) CTX1B equivalents extract detection (LOD), being...

10.1080/19440049.2012.660707 article EN Food Additives & Contaminants Part A 2012-03-07

The increasing occurrence of puffer fish containing tetrodotoxin (TTX) in the Mediterranean could represent a major food safety risk for European consumers and threaten fishing industry. work presented herein describes development new enzyme linked immunosorbent assay (mELISA) based on immobilization TTX through dithiol monolayers self-assembled maleimide plates, which provides an ordered oriented antigen favors antigen–antibody affinity interaction. mELISA was found to have limit detection...

10.1021/acs.analchem.5b02158 article EN Analytical Chemistry 2015-10-01

Tetrodotoxin (TTX) is a marine toxin responsible for many intoxications around the world. Its presence in some pufferfish species and, as recently reported, shellfish, poses serious health concern. Although TTX not routinely monitored, there need fast, sensitive, reliable, and simple methods its detection quantification. In this work, we describe use of an automated patch clamp (APC) system with Neuro-2a cells determination contents samples. The showed IC50 6.4 nM were affected by muscle,...

10.3390/md22040176 article EN cc-by Marine Drugs 2024-04-15

The frequency and intensity of Pseudo-nitzschia spp. blooms along the coast Catalonia have been increasing over past 20 years. As species from this genus that are documented as toxigenic found in local waters, with both toxic nontoxic cooccurring same bloom, there is a need to develop management tools for discriminating difference. Currently, differentiation requires time-consuming electron microscopy distinguish taxonomic features would allow identification species, cryptic can still remain...

10.1128/aem.01978-10 article EN Applied and Environmental Microbiology 2010-12-31
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